Results 41 to 50 of about 216,757 (314)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

برامج الفيديو التفاعلي التعليمية: الأسس النظرية، والتطبيقات العملية [PDF]

open access: yesتکنولوجیا التعلیم: سلسلة دراسات و بحوث
يقدم هذا المقال رؤيا شاملة لبرامج الفيديو التفاعلي التعليمية من خلال استعراض أبعاد عدة. يبدأ بتعريف مفهوم الفيديو التفاعلي، وتسليط الضوء على مزاياه التربوية، مثل زيادة تفاعل المتعلم، وتحسين الاحتفاظ بالمعلومات، ودعم المسارات التعليمية المخصصة.
وليد يوسف محمد إبراهيم
doaj   +1 more source

Ukrainian E-Learning Platforms for Schools: Evaluation of Their Functionality

open access: yesInternational Review of Research in Open and Distributed Learning, 2022
This article defines 27 criteria for evaluating the functionality of e-learning platforms, grouped into three macro groups: (a) learning management, (b) learning content management, and (c) communications and collaboration tools.
Maryna Zhenchenko   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Exploring teachers’ beliefs about learning principles

open access: yesFrontiers in Education
Teachers hold conscious or subconscious beliefs about pedagogy, education and learning that are deeply ingrained and steer their daily pedagogical reasoning.
Erik Meij   +3 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

What learning theories can teach us in designing neurofeedback treatments

open access: yesFrontiers in Human Neuroscience, 2014
Popular definitions of neurofeedback point out that neurofeedback is a process of operant conditioning which leads to self-regulation of brain activity. Self-regulation of brain activity is considered to be a skill.
Ute eStrehl
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Investigation on the Amount Of Attention Given To Educational Applications Of Learning Theories In Educational Math Films In Primary-School Level [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2006
The present research aims at appraising educational applications of learning theories practiced in mathematics instructional videos at primary level produced by Educational Technology Bureau of Ministry of Education in Iran.
Mohammad Fathinia
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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