Results 131 to 140 of about 1,203,050 (307)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Epicuticular Wax Alkanes of Scutellaria Lateriflora L. Leaves [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1987 The dried aerial parts of scutellaria lateriflora L. (family Labiatae), have been used for many years as a domestic remedy for epilepsy, hysteria, and nervous tension states.
Shahram Yaghmai +1 more
doaj
Existing antioxidant levels are more important in acclimation to supplemental UV-B irradiation than inducible ones: Studies with high light pretreated tobacco leaves [PDF]
, 2012 Greenhouse grown tobacco plants were exposed to supplemental ultraviolet irradiation (280-400 nm, UV-B centered) for 6 days and changes in their photosynthesis (gas exchange and electron transport) and general and specific antioxidant activities were ...
Majer, Petra, Hideg, Éva
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Journal clipping, Mosquito War News, Oak Leaves, June 20, 1925
, 1925 This is an item from the William Crawford Gorgas Papers. This collection includes material created by and written about Gorgas, as well as material created by Gorgas' family members.
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, 2005 We discuss a simple sparse linear problem that is hard to learn with any algorithm that uses a linear combination of the training instances as its weight vector. The hardness holds even if we allow the learner to embed the instances into any higher dimensional feature space (and use a kernel function to define the dot product between the embedded ...
Warmuth, Manfred, Vishwanathan, S
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Leaves from a Christmas bough /
Decorated in the style of a medieval manuscript with illustrations heightened in gold and decorative initials throughout.Chromolithographed illustrated title page heightened in gold.Mode of access: Internet.Library's copy with elaborate inscription on ...
Leighton Bros. (London, England), printer. +3 more
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Symptomless infection of Rhynchosporium secalis on leaves of winter barley
, 1990 Areas of leaf blotch lesions were assessed visually on green leaves sampled from a barley crop in March and April. When these leaves were examined further, firstly on a light table and then microscopically after clearing and staining, infected areas ...
Fitt, B. D. L. +4 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source