Results 161 to 170 of about 811,099 (259)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
, 1968 The Fall 1968 edition of the Anderson College journal of art and literature, Ivy Leaves. The names of the known editors for this issue of Ivy Leaves were Mike Creswell, Debbie Hannon, Ann Skidmore, Karen Galway, Hank Richardson, Jim Taylor, Carolyn ...
Ivy Leaves Editorial Staff,
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
, 1966 The Spring 1966 edition of the Anderson College journal of art and literature, Ivy Leaves. The names of the known editors for this issue of Ivy Leaves were Jackie Anderson, Mike Hatfield, Frank Peake, Sherril Vaughan, Catharine Davis, Tinka White ...
Ivy Leaves Editorial Staff,
core
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
, 1967 The Spring 1967 edition of the Anderson College journal of art and literature, Ivy Leaves. The names of the known editors for this issue of Ivy Leaves were Danny Byron Collins, Tinka White, Connie Mahaffey, Kathleen Inabinet, Len Farmer, Dick Madden ...
Ivy Leaves Editorial Staff,
core
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
, 2018 The 2018 edition of the Anderson University journal of art and literature, Ivy Leaves. The names of the known editors for this issue of Ivy Leaves were Haley Schvaneveldt, Olivia Strickland, Ruthie Snow, Rachael Barfield, Jacob Cavett, Claire Foxx, Ana ...
Ivy Leaves Editorial Staff,
core
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source