Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Physiological and Transcriptomic Evaluation of Drought Tolerance in Alfalfa (<i>Medicago sativa</i> L.) and Identification of Resilient Germplasm. [PDF]
Sun L +6 more
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Convergent evolution in the late Permian megaphyllous leaves of the Noeggerathiales progymnosperm Paratingia and the cycad Plagiozamites. [PDF]
Qin YF +5 more
europepmc +1 more source
Blue light receptor phot2 collaborates with NRL-30 to negatively regulate immunity by reducing mitochondrial protein PRXIIF stability in potato. [PDF]
Qiu H +14 more
europepmc +1 more source
Integrated In Silico Prioritization of Antidiabetic Phytochemicals from <i>Uvaria chamae</i> P. Beauv. Based on Docking, Induced-Fit Docking, QSAR, and ADMET Analyses. [PDF]
Sovegnon T +8 more
europepmc +1 more source
Jasmonoyl-L-Isoleucine Induces Systemic Photosynthetic Responses to Local Heat Stress by Contributing to Abscisic Acid Accumulation. [PDF]
Kuznetsova D, Vodeneev V, Ladeynova M.
europepmc +1 more source
<i>Adenia sajoreciae</i> (Passifloraceae), a new species from Kenya and its phylogenetic placement. [PDF]
Kipkemoi E +9 more
europepmc +1 more source

