Results 151 to 160 of about 265,644 (356)

Inflammatory and anti-inflammatory effects of soybean agglutinin

Brazilian Journal of Medical and Biological Research, 1997
Soybean agglutinin (SBA) lectin, a protein present in raw soybean meals, can bind to and be extensively endocytosed by intestinal epithelial cells, being nutritionally toxic for most animals.
Benjamin C.F., Figueiredo R.C., Henriques M.G.M.O., Barja-Fidalgo C.   +3 more
doaj  

Purification of the lectin from Datura stramonium [PDF]

, 1978
David C. Kilpatrick, M. M. Yeoman
openalex   +1 more source

Exploring the Impact of Phenanthroline‐Based Glycoconjugated Ru(II) Polypyridyl Photosensitizers on Metastasis‐Related Processes

Chemistry – A European Journal, EarlyView.
A novel family of water‐soluble, nontoxic, and phosphorescent N‐glycosylated Ru(II) phenanthroline‐based complexes are reported. They exhibit photoselectivity indexes ranging from 10 to 44 in PC‐3 cells, while impacting cell migration and resistance to detachment after irradiation with blue light.
Elena de la Torre‐Rubio, María‐Selma Arias‐Pérez, Lourdes Gude, Tomás Cuenca, Cristina García‐Iriepa, Eva Royo   +5 more
wiley   +1 more source

Glycans and Chirality: Stereoselectivity at the Core of DC‐SIGN's Recognition. A Novel View of the Optimum Minimal Ligand Epitope

Chemistry – A European Journal, EarlyView.
The stereochemical diversity of the “glycan code” enables similar chiral motifs to arise from both D‐ and L‐sugars. Focused on DC‐SIGN–glycan recognition, two diverse monosaccharide scaffolds, D‐Man (D‐Rha) and L‐Gal (L‐Fuc), maintain the exquisite stereochemistry encoded in the minimal binding epitope.
J. Daniel Martínez, Reyes Núñez‐Franco, Pablo Valverde, Sandra Delgado, Ana Ardá, Jesús Jiménez‐Barbero, Gonzalo Jiménez‐Oses, F. Javier Cañada   +7 more
wiley   +1 more source

Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and Worms

Cytoskeleton, EarlyView.
ABSTRACT Cells have an intrinsic ability to rapidly respond to environmental change to regulate cell cycle progression and membrane organisation, thereby affecting cell growth and division. The actin cytoskeleton is a highly dynamic complex of proteins that can rapidly reorganise to change the growth pattern of a cell.
Holly R. Brooker, Karen Baker, Marina Ezcurra, Philippe P. Laissue, Lin Wang, Michael A. Geeves, Jennifer M. Tullet, Daniel P. Mulvihill   +7 more
wiley   +1 more source

Sustainable Synthesis, Characterization, Cellular Effects of Gold Nanoparticles and Their Applications as Therapeutics in Cancer Therapy

ChemPlusChem, EarlyView.
Gold nanoparticles (AuNPs) are widely used in biomedicine, electronics, catalysis, and environmental science. Conventional synthesis relies on harsh chemicals, driving interest in eco‐friendly methods using plants, bacteria, fungi, and algae. Biomolecules like polyphenols, proteins, and fatty acids aid nanoparticle synthesis under mild conditions. This
Youfeng Yue, Akihiro Moriyama, Marie Mita, Yue Yu   +3 more
wiley   +1 more source

Uncovering New Therapeutic Targets for Amyotrophic Lateral Sclerosis and Neurological Diseases Using Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
Although attractive for relevance to real‐world scenarios, real‐world data (RWD) is typically used for drug repurposing and not therapeutic target discovery. Repurposing studies have identified few effective options in neurological diseases such as the rare disease, amyotrophic lateral sclerosis (ALS), which has no disease‐modifying treatments ...
Mohammadali Alidoost, Jeremy Y. Huang, Georgia Dermentzaki, Anna S. Blazier, Giorgio Gaglia, Timothy R. Hammond, Francesca Frau, Mary Clare McCorry, Dimitry Ofengeim, Jennifer L. Wilson   +9 more
wiley   +1 more source

Alterations in Lectin Binding to Guinea Pig Spermatozoa Accompanying in vitro Capacitation and the Acrosome Reaction [PDF]

, 1979
Martin A. Schwarz, James K. Koehler
openalex   +1 more source

Confirmation of Fixed Quarterly Riliprubart Regimen in Patients with Cold Agglutinin Disease Using Population PK/PD and Exposure‐Response Analyses

Clinical Pharmacology &Therapeutics, EarlyView.
Riliprubart is a second‐generation, humanized immunoglobulin G4 that inhibits only the activated form of the C1s component of the proximal classical complement pathway. The clinical studies of riliprubart conducted thus far for the treatment of cold agglutinin disease (CAD), a rare autoimmune disease, include a Phase 1 first‐in‐human study in healthy ...
Timothy Chow, Marek Wardecki, Michael Storek, Nancy Wong   +3 more
wiley   +1 more source

Isolation of mammalian tRNA^Aspand tRNA^Tyrby lectin-Sepharose affinity column chromatography

, 1977
Norihiro Okada, Nobuko Shindo‐Okada, Susumu Nishimura   +2 more
openalex   +2 more sources