Results 251 to 260 of about 345,151 (401)

Tumor desialylation surpasses anti‐PD‐L1 checkpoint therapy in restoring anti‐tumor immunity in a murine model for colorectal cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Our research highlights how tumor sialylation affects tumor growth and reshapes the immune tumor microenvironment in colorectal cancer. We demonstrate for the first time that complete removal of sialic acids from colorectal tumor cells elicits a robust anti‐tumor immune response, but does not enhance anti‐PD‐L1 blockade efficacy.
Irene van der Haar Àvila   +11 more
wiley   +1 more source

The chemical characterization of favin, a lectin isolated from Vicia faba.

open access: hybrid, 1979
John J. Hemperly   +3 more
openalex   +1 more source

Targeting the ST3 beta‐galactoside alpha‐2,3‐sialyltransferase 1 (ST3Gal1) as a potential therapeutic strategy to overcome anti‐VEGF resistance in endometrial cancer

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the role of ST3 beta‐galactoside alpha‐2,3‐sialyltransferase 1 (ST3Gal1) in endometrial cancer (EC) progression and its potential as a therapeutic target to enhance the efficacy of antiangiogenic treatment. Methods ST3Gal1 expression and its clinical relevance were analyzed in EC tissues.
Chia‐Hao Liu   +8 more
wiley   +1 more source

Cold atmospheric plasma combined with nanoparticles in cancer therapy

open access: yesInterdisciplinary Medicine, EarlyView.
Cold atmospheric plasma (CAP) generates a range of reactive oxygen and nitrogen species (RONS), including singlet oxygen (1O2), hydrogen peroxide (H2O2), hydroxyl radicals (·OH), nitrate (NO3− ${{\text{NO}}_{3}}^{-}$), and nitrite (NO2− ${{\text{NO}}_{2}}^{-}$), which induce oxidative stress and apoptosis in cancer cells.
Yunhao Wang   +7 more
wiley   +1 more source

Evolution of genotypic and phenotypic diversity in multispecies biofilms. [PDF]

open access: yesNPJ Biofilms Microbiomes
Amador CI   +10 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy