Results 121 to 130 of about 2,513,226 (377)

Mannose binding lectin plays a crucial role in innate immunity against yeast by enhanced complement activation and enhanced uptake of polymorphonuclear cells

BMC Microbiology, 2008
Background Mannose binding lectin (MBL) is an important host defence protein against opportunistic fungal pathogens. This carbohydrate-binding protein, an opsonin and lectin pathway activator, binds through multiple lectin domains to the repeating sugar ...
Herpers Bjorn L, Scharringa Jelle, Hoepelman Andy IM, van Asbeck Eveline C, Verhoef Jan   +4 more
doaj   +1 more source

Gesture Recognition with a Skeleton-Based Keyframe Selection Module [PDF]

arXiv, 2021
We propose a bidirectional consecutively connected two-pathway network (BCCN) for efficient gesture recognition. The BCCN consists of two pathways: (i) a keyframe pathway and (ii) a temporal-attention pathway. The keyframe pathway is configured using the skeleton-based keyframe selection module. Keyframes pass through the pathway to extract the spatial
arxiv  

Collectin-11/MASP Complex Formation Triggers Activation of the Lectin Complement Pathway - The Fifth Lectin Pathway Initiation Complex [PDF]

Journal of Innate Immunity, 2012
Collectins and ficolins are important in the clearance of endogenous and exogenous danger materials. A new human collectin-11 was recently identified in low concentration in serum in complex with mannose-binding lectin (MBL)/ficolin-associated serine proteases. Collectin-11 binds to carbohydrate residues present on various microorganisms.
Ma, Ying Jie, Skjoedt, Mikkel-Ole, Garred, Peter   +2 more
openaire   +4 more sources

The C-Type Lectin Receptor CLECSF8/CLEC4D Is a Key Component of Anti-Mycobacterial Immunity [PDF]

, 2015
Open Access funded by Wellcome Trust: Under a Creative Commons license Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved. Acknowledgments We would like to thank S. Hardison, P. Redelinghuys, J. Taylor, C. Wallace, A.
Alisjahbana, Bachti, Besra, Gurdyal S, Brown, Gordon D, Drummond, Rebecca A, Govender, Dhirendra, Hoving, Jennifer C, Jacobs, Muazzam, Keeton, Roanne, Kerscher, Bernhard, Marakalala, Mohlopheni J, Netea, Mihai G, Ottenhoff, Tom H M, Plantinga, Theo S, Reid, Delyth M, van Crevel, Reinout, van de Vosse, Esther, van Laarhoven, Arjan, Willment, Janet A, Wilson, Gillian J, Yamasaki, Sho   +19 more
core   +2 more sources

Alpha-tocopherol exerts protective function against the mucotoxicity of particulate matter in amphibian and human goblet cells [PDF]

, 2020
Exposure to particulate matter (PM) in ambient air is known to increase the risk of cardiovascular disorders and mortality. The cytotoxicity of PM is mainly due to the abnormal increase of reactive oxygen species (ROS), which damage cellular components ...
Bang, Woo Young, Cho, Hanna, Kim, Ha Eun, Kwon, Taeg Kyu, Kwon, Taejoon, Park, Tae Joo, Sim, Hyo Jung, Yang, Hee-Sun   +7 more
core   +1 more source

Machine‐Learning‐Aided Advanced Electrochemical Biosensors

Advanced Materials, EarlyView.
Electrochemical biosensors are highly sensitive, portable, and versatile. Advanced nanomaterials enhance their performance, while machine learning (ML) improves data analysis, minimizes interference, and optimizes sensor design. Despite progress in both fields, their combined potential in diagnostics remains underexplored.
Andrei Bocan, Roozbeh Siavash Moakhar, Carolina del Real Mata, Max Petkun, Tristan De Iure‐Grimmel, Sripadh Guptha Yedire, Hamed Shieh, Arash Khorrami Jahromi, Sahar Sadat Mahshid, Sara Mahshid   +9 more
wiley   +1 more source

Lectin Complement Pathway Activation is Associated with Massive Proteinuria in PLA2R-Positive Membranous Nephropathy: A Retrospective Study

International Journal of General Medicine, 2023
Jiayi Li,1,2 Jiao Zhang,2 Xu Wang,2 Xumin Zheng,2 Hongmei Gao,2 Shimin Jiang,2 Wenge Li1,2 1Department of Nephrology, Peking University China-Japan Friendship School of Clinical Medicine, Beijing, People’s Republic of China; 2Department of ...
Li J, Zhang J, Wang X, Zheng X, Gao H, Jiang S, Li W   +6 more
doaj  

Genetically-defined deficiency of mannose-binding lectin is associated with protection after experimental stroke in mice and outcome in human stroke. [PDF]

PLoS ONE, 2010
BackgroundThe complement system is a major effector of innate immunity that has been involved in stroke brain damage. Complement activation occurs through the classical, alternative and lectin pathways.
Alvaro Cervera, Anna M Planas, Carles Justicia, Xabier Urra, Jens C Jensenius, Ferran Torres, Francisco Lozano, Angel Chamorro   +7 more
doaj   +1 more source

Inverse Optimization on Hierarchical Networks: An Application to Breast Cancer Clinical Pathways [PDF]

arXiv, 2021
Clinical pathways are standardized processes that outline the steps required for managing a specific disease. However, patient pathways often deviate from clinical pathways. Measuring the concordance of patient pathways to clinical pathways is important for health system monitoring and informing quality improvement initiatives.
arxiv  

Mass Spectrometry in the Elucidation of the Glycoproteome of Bacterial Pathogens [PDF]

, 2010
Presently some three hundred post-translational modifications are known to occur in bacteria in vivo. Many of these modifications play critical roles in the regulation of proteins and control key biological processes.
Graham, Robert L. J., Hess, Sonja
core   +1 more source