Results 161 to 170 of about 104,017 (255)

The Lectin Pathway-A Dominant Pattern of the Complement System Activation in Primary Focal Segmental Glomerulosclerosis? [PDF]

Kidney Int Rep
Zagorec N, Horvatić I, Šenjug P, Sović S, Galešić K, Galešić Ljubanović D.   +5 more
europepmc   +1 more source

The Influence of the Lectin Pathway of Complement Activation on Infections of the Respiratory System. [PDF]

Front Immunol, 2020
Świerzko AS, Cedzyński M.
europepmc   +1 more source

The lectin complement pathway in human contusions

Immunobiology, 2016
Daiana De Blasio, Stefano Fumagalli, Luca Longhi, Franca Orsini, Fabrizio Ortolano, Elisa R. Zanier, Silvia Ferrari, Giulio Goti, Peter Garred, Edoardo Picetti, Marco Locatelli, Anna Bernardi, Marco Gobbi, Nino Stocchetti, Maria-Grazia De Simoni   +14 more
openaire   +1 more source

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

Corrigendum: Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs. [PDF]

Front Immunol
Hurler L, Toonen EJM, Kajdácsi E, van Bree B, Brandwijk RJMGE, de Bruin W, Lyons PA, Bergamaschi L, Cambridge Institute of Therapeutic Immunology Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration, Sinkovits G, Cervenak L, Würzner R, Prohászka Z.   +12 more
europepmc   +1 more source

The lectin pathway triggered by activated platelets

Immunobiology, 2012
Huda Kozarcanin, Kristina N. Ekdahl, Bo Nilsson   +2 more
openaire   +1 more source

Pig Seminal Plasma Extracellular Vesicles Enhance Motility During Preservation of Epididymal Spermatozoa but Impair Capacitation and IVF Parameters

Andrology, EarlyView.
ABSTRACT Background Extracellular vesicles (EVs) produced by accessory sex glands play a key role in sperm functionality, influencing motility, viability, acrosome integrity, metabolic activity, and capacitation. Most studies on the effects of EVs on spermatozoa have focused on ejaculated spermatozoa, which have already been exposed to their own native
Ana Moya‐Fernández, Santa María Toledo‐Guardiola, Peter Silke, Sergio Navarro‐Serna, Carmen Matás   +4 more
wiley   +1 more source

Monovalent mannose‐glycoconjugates of sulforaphane reprogram human dendritic cells via NFATc1 to induce immune tolerance under inflammatory conditions

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez, Camila Leiva‐Castro, Ana M. Múnera‐Rodríguez, Macarena Martínez‐Bailén, Ana T. Carmona, Soledad López‐Enríquez, Francisca Palomares   +6 more
wiley   +1 more source

The Lectin Pathway of the Complement System-Activation, Regulation, Disease Connections and Interplay with Other (Proteolytic) Systems. [PDF]

Int J Mol Sci
Dobó J, Kocsis A, Farkas B, Demeter F, Cervenak L, Gál P.   +5 more
europepmc   +1 more source

Randomised, phase 1 evaluation of the safety, tolerability, pharmacokinetics and pharmacodynamics of iptacopan in healthy volunteers

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Overactivation of the alternative pathway (AP) underlies several diseases. Iptacopan is an oral, first‐in‐class, highly potent specific inhibitor of factor B, a key AP protease. Experimental Approach The analysis included data from two phase 1 randomised, volunteer‐blinded, placebo‐controlled studies: Study 1, a single ...
Irina Baltcheva, Guido Junge, Kenneth Kulmatycki, Robert Schmouder, Anna Schubart, Marie‐Anne Valentin   +5 more
wiley   +1 more source