European Journal of Heart Failure, EarlyView.The analysis workflow, findings and potential clinical consequences of iron deficiency in heart failure (HF). From 881 patients with worsening HF, whole blood transcriptome was analysed using the Affymetrix Human Transcriptome Array (HTA) 2.0. Subjects were stratified according to their transferrin saturation (TSAT) levels as iron‐deficient (TSAT <20%)
Niels Grote Beverborg +17 more
wiley +1 more source
Inhibition of the lectin pathway of complement ameliorates hypocomplementemia and restores serum bactericidal activity in patients with severe COVID-19. [PDF]
Clin Transl Med, 2022 Lynch NJ +8 more
europepmc +1 more source
Activation of the Lectin Pathway by Natural IgM in a Model of Ischemia/Reperfusion Injury [PDF]
, 2006 Ming Zhang +9 more
openalex +1 more source
Marine Algae‐Derived Bioactives: A Sustainable Resource for the Food and Agriculture Industries
Food Frontiers, EarlyView.Algae are widely used in food and agriculture due to their bioactive compounds and are an eco‐friendly natural preservative and low carbon farming method. However, the problems regarding safety and acceptance still remain as tools like nanotechnology make improvements.
Sara Chadorshabi +3 more
wiley +1 more source
Correction: Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. [PDF]
J Biol Chem, 2023 Nagy ZA +12 more
europepmc +1 more source
Emerging Frontiers in Food Allergy Treatment: Progress, Challenges, and Prospects
Food Frontiers, EarlyView.Food allergy is a rising global health concern with limited treatment options beyond allergen avoidance and emergency care. This review explores the evolving therapeutic landscape, highlighting advances in allergen immunotherapy, biologics such as monoclonal antibodies, and emerging vaccine‐based approaches.
Ayesha Zahid +3 more
wiley +1 more source
Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model. [PDF]
Front Immunol, 2022 Golomingi M +9 more
europepmc +1 more source
Germline rare variants of lectin pathway genes predispose to asymptomatic SARS-CoV-2 infection in elderly individuals. [PDF]
Genet Med, 2022 D'Alterio G +27 more
europepmc +1 more source
Which Came First, the Lectin/Classical Pathway or the Alternative Pathway of Complement?
Immunobiology, 2002 It is a widely accepted canon of immunology that the alternative pathway is more primitive and hence older in evolutionary terms than the lectin/classical pathway. This idea has been reinforced by the discovery of "C3" and "factor B" proteins in invertebrate species. However, it is clear that the gene duplications which gave rise to C3/C4/C5 and factor
openaire +2 more sources