Natural inhibitors of the lectin pathway
Immunobiology, 2012 Péter Závodszky +3 more
openaire +2 more sources
iMetaMed, EarlyView.Graphical abstract of the major mechanisms of Everolimus in ulcerative colitis: Everolimus, a selective mTORC1 inhibitor, protects against ulcerative colitis through a dual mechanism. First, Eve directly suppresses CLEC4E/Syk/NF‐κB signaling, thereby reducing pro‐inflammatory cytokine production and preserving intestinal barrier integrity.
Jing Chen +6 more
wiley +1 more source
Association Of Mannose Binding Lectin (MBL) Gene Mutations With Other Pathway Defects Spanning Innate And Adaptive Immune Responses [PDF]
, 2011 M.B. Pate +3 more
openalex +1 more source
Cold atmospheric plasma combined with nanoparticles in cancer therapy
Interdisciplinary Medicine, EarlyView.Cold atmospheric plasma (CAP) generates a range of reactive oxygen and nitrogen species (RONS), including singlet oxygen (1O2), hydrogen peroxide (H2O2), hydroxyl radicals (·OH), nitrate (NO3− ${{\text{NO}}_{3}}^{-}$), and nitrite (NO2− ${{\text{NO}}_{2}}^{-}$), which induce oxidative stress and apoptosis in cancer cells.
Yunhao Wang +7 more
wiley +1 more source
The role of the lectin VIP36 in the early secretory pathway
, 2010 Lectins are of emerging importance for quality control and intracellular transport of glycoproteins in mammalian cells. One of the most prominent lectins involved in intracellular transport is ERGIC-53, which belongs to the family of L-type lectins. ERGIC-53 mediates the ER export of several glycoproteins like cathepsin Z, α1-antitrypsin (α1-AT) or ...
openaire +3 more sources
Soluble C5b‐9 (sC5b‐9) in Pediatrics—A Clinical Assessment
Journal of Clinical Laboratory Analysis, EarlyView.The sc5b9 assay is a simple laboratory‐developed test that can be used in specific patients to monitor the course of disease, severity, or response to therapy. Future studies using this assay, which show excellent adaptability to a clinical laboratory, will reveal the multiple uses of testing for complement activation.
Ridwan B. Ibrahim +3 more
wiley +1 more source
Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. [PDF]
J Biol Chem, 2022 Nagy ZA +12 more
europepmc +1 more source
Factors of the Lectin Pathway of Complement Activation and Their Clinical Associations in Neonates [PDF]
, 2012 Maciej Cedzyński +2 more
openalex +1 more source
Climate change and the antinutrient–antioxidant puzzle in common bean seeds
Journal of the Science of Food and Agriculture, EarlyView.Abstract Non‐proteinaceous and proteinaceous antinutrients in common bean (Phaseolus vulgaris L.) seeds can negatively affect human nutrition by reducing mineral bioavailability and impairing protein digestibility during digestion, respectively. However, many of these compounds also possess strong antioxidant properties that can help protect the plant ...
Juan Vorster +5 more
wiley +1 more source
Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides. [PDF]
ACS Chem Biol, 2022 Dürvanger Z +14 more
europepmc +1 more source