Results 191 to 200 of about 103,608 (291)

Endocrine Resistance Score Based on Three Key Genes Predicts Prognosis and Reveals Potential Therapeutic Targets for ER+HER2− Breast Cancer

open access: yesCell Proliferation, EarlyView.
We generated endocrine‐resistant BC cell lines and identified CLEC3A, PCDH10, and ST3GAL1 as key endocrine‐resistant genes. More importantly, we validated their role in mediating resistance through PI3K‐AKT signalling and developed a predictive ERS with strong clinical relevance.
Liqin Ping   +7 more
wiley   +1 more source

The lectin pathway triggered by activated platelets

open access: yesImmunobiology, 2012
Huda Kozarcanin   +2 more
openaire   +1 more source

Sutimlimab in Patients With Cold Agglutinin Disease (CAD): Results From a Managed Access Program

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Cold agglutinin disease (CAD) is a low‐grade lymphoproliferative disorder accounting for 15%–30% of patients suffering from autoimmune hemolytic anemias. The clonal B cells produce autoantibodies primarily of the IgM‐κ class that cause agglutination of red blood cells (RBCs) at temperatures ≤ 37°C and activate the classical complement pathway ...
Sandra Maria Frey   +5 more
wiley   +1 more source

The Lectin Complement Pathway in Patients with Necrotizing Soft Tissue Infection

open access: gold, 2016
Marco Bo Hansen   +7 more
openalex   +1 more source

Use of the oral microbiota as screening test to identify children at risk for caries development. A systematic review of longitudinal studies

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract This study investigated trends in oral microbiota composition (index test) that could indicate potential candidates to identify children at risk for dental caries development compared with visual/tactile examination (reference test). MEDLINE/PubMed, Web of Science, Embase, Scopus, Lilacs, SciELO, and Google Scholar databases were searched up ...
Heitor Sales de Barros Santos   +3 more
wiley   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

open access: yesThe FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk   +8 more
wiley   +1 more source

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