Results 221 to 230 of about 159,204 (339)

TREM2 Downregulation Disrupts Microglial Function and Synaptic Pruning Through RA/RARα Signaling: Mechanisms Underlying Autism‐Like Behaviors

Pediatric Discovery, EarlyView.
Downregulation of TREM2 induces autism‐like behaviors in healthy rats by impairing microglial function and triggering aberrant synaptic pruning. RA/RARα signaling pathway modulates alterations in TREM2 expression. Serum sTREM2 levels correspond to alterations in brain TREM2 expression.
Min Lu, Kexin Bai, Yali Bai, Yuan Miao, Tingjiao Zhao, Yi Yang, Jie Chen, Ting Yang, Tingyu Li, Hua Wei   +9 more
wiley   +1 more source

Exosome-Mediated Lectin Pathway and Resistin-MIF-AA Metabolism Axis Drive Immune Dysfunction in Immune Thrombocytopenia. [PDF]

Adv Sci (Weinh)
Li J, Wang X, Chen Y, Sun X, Fu L, Xin Q, Zhang H, Qin B, Sun N, Li Y, Xu Y, Yang H, Huo D, Dong Y, Wang S, Zhao M, Lin Q, Wang F, Yue B, Gao Y, Jiang Y, Guo R.   +21 more
europepmc   +1 more source

Lectin pathway proteins of the complement system in normotensive pregnancy and pre‐eclampsia [PDF]

, 2019
Julie Brogaard Larsen, Anita Sylvest Andersen, Christine Lodberg Hvas, Steffen Thiel, Michael R. Lassen, Anne‐Mette Hvas, Anette Tarp Hansen   +6 more
openalex   +1 more source

Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates

PROTEOMICS, EarlyView.
ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre, Jens Hamar, Monica B. Urias, Dietmar Kültz   +3 more
wiley   +1 more source

The complement lectin pathway protein MAp19 and out-of-hospital cardiac arrest: Insights from two randomized clinical trials [PDF]

, 2019
John Bro-Jeppesen, Anni Nørgaard Jeppesen, Simon Haugaard, Anne Troldborg, Christian Hassager, Jesper Kjærgaard, Hans Kirkegaard, Michael Wanscher, Anne‐Mette Hvas, Steffen Thiel   +9 more
openalex   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

The Influence of the Lectin Pathway of Complement Activation on Infections of the Respiratory System. [PDF]

Front Immunol, 2020
Świerzko AS, Cedzyński M.
europepmc   +1 more source

Circulating lectin pathway proteins do not predict short-term cardiac outcomes after myocardial infarction [PDF]

, 2019
Charlotte B. Holt, Jakob Appel Østergaard, Steffen Thiel, Troels Krarup Hansen, Linda Mellbin, Peder Sörensson, Mette Bjerre   +6 more
openalex   +1 more source

The lectin pathway triggered by activated platelets

Immunobiology, 2012
Huda Kozarcanin, Kristina Nilsson Ekdahl, Bo Nilsson   +2 more
openaire   +2 more sources

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

Small Methods, EarlyView.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz, Nima Pourafzal, Audrey T. Zhu, Zhongyuan Guo, Ronnie H. Fang, Liangfang Zhang   +5 more
wiley   +1 more source