Results 241 to 250 of about 3,190,451 (315)

The lectin complement pathway in human contusions

open access: yesImmunobiology, 2016
Daiana De Blasio   +14 more
openaire   +1 more source

T Cell Heterogeneity Shaped by Alternative Splicing Predicts Prognosis in Hepatocellular Carcinoma

open access: yesCancer Science, EarlyView.
T cell‐specific alternative splicing events shape T cell heterogeneity in HCC. Single‐cell analysis identified two splicing‐defined T cell subpopulations with distinct functional profiles. Subpopulation‐associated splicing events were used to construct a prognostic model predicting patient survival.
Xiaohui Peng   +11 more
wiley   +1 more source

TFPI inhibits lectin pathway of complement activation by direct interaction with MASP‐2

open access: yesEuropean Journal of Immunology, 2015
Mischa P. Keizer   +8 more
semanticscholar   +1 more source

Levels in Plasma of the Serine Proteases and Associated Proteins of the Lectin Pathway Are Altered in Patients with Systemic Lupus Erythematosus

open access: yesJournal of Rheumatology, 2015
A. Troldborg   +5 more
semanticscholar   +1 more source

The lectin pathway triggered by activated platelets

open access: yesImmunobiology, 2012
Huda Kozarcanin   +2 more
openaire   +1 more source

Garadacimab for the long‐term prophylaxis of hereditary angioedema

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün   +5 more
wiley   +1 more source

[Lectin pathway and pathophysiology].

open access: yesNihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 1996
openaire   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

open access: yesThe FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto   +9 more
wiley   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

open access: yesThe FEBS Journal, EarlyView.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs   +7 more
wiley   +1 more source

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