Results 1 to 10 of about 23,222 (158)

Mannose-binding lectin deficiency with eosinophilic meningoencephalitis due to Angiostrongylus cantonensis in children: a case series [PDF]

Journal of Medical Case Reports, 2011
Introduction Eosinophilic meningitis, a potentially fatal disease caused by Angiostrongylus cantonensis, is considered an emerging infectious disease.
de Paula-Almeida Olga, Martínez-Alderete René H, Bu-Coifiu-Fanego Raisa, Dorta-Contreras Alberto J, Padilla-Docal Bárbara, Reiber Hansotto, Jensenius Jens   +6 more
doaj   +3 more sources

Identification of novel blood-borne soluble binding partners of factor H-related proteins [PDF]

Scientific Reports
The deposition of circulating complement factor H-related (FHR) proteins in tissues around the body has been implicated in a series of complement-mediated diseases.
Jiaqi Tang, Franziska Woerz, Tina Beyer, Karsten Boldt, Sonika Rathi, Shiying Zhao, Lasse Wolfram, Marius Ueffing, Simon J. Clark   +8 more
doaj   +2 more sources

Evaluation of Serum Complement Components in Pediatric IgA Vasculitis: A Case-Control Study [PDF]

Children
Background: IgA vasculitis (IgAV) represents the most frequently seen form of vasculitis among children. Although it often resolves without intervention, renal involvement (IgAV nephritis) poses a risk for long-term complications. Although the lectin and
Raziye Burcu Taşkın, Güzide Aksu, Sait Şen, Gülden Hakverdi, Burçe Emine Dörtkardeşler, Secil Conkar Tunçay   +5 more
doaj   +2 more sources

Proteins of the lectin pathway of the complement system activation: immunobiological functions, genetics and involvement in the pathogenesis of human diseases

Инфекция и иммунитет, 2022
The complement system is the most ancient components in the innate immunity, mainly functioning to primarily eliminate bacterial agents intravascularly.
Marina V. Smolnikova, Sergey Yu. Tereshchenko   +1 more
doaj   +1 more source

Mannose-binding lectin 2 gene and risk of adult glioma. [PDF]

PLoS ONE, 2013
The immune system is likely to play a key role in the etiology of gliomas. Genetic polymorphisms in the mannose-binding lectin gene, a key activator in the lectin complement pathway, have been associated with risk of several cancers.To examine the role ...
Dominique S Michaud, Afshan Siddiq, David G Cox, Danielle M Backes, Federico C F Calboli, Michael E Sughrue, J Michael Gaziano, Jing Ma, Meir Stampfer, Shelley S Tworoger, David J Hunter, Carlos A Camargo, Andrew T Parsa   +12 more
doaj   +1 more source

MASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19 [PDF]

Genetics and Molecular Biology, 2021
Components of the complement system and atypical parameters of coagulation were reported in COVID-19 patients, as well as the exacerbation of the inflammation and coagulation activity.
Valéria Bumiller-Bini, Camila de Freitas Oliveira-Toré, Tamyres Mingorance Carvalho, Gabriela Canalli Kretzschmar, Letícia Boslooper Gonçalves, Nina de Moura Alencar, Miguel Angelo Gasparetto Filho, Marcia Holsbach Beltrame, Angelica Beate Winter Boldt   +8 more
doaj   +1 more source

Critical role of lectin pathway mediated by MBL-associated serine proteases in complement activation for the pathogenesis in systemic lupus erythematosus

Heliyon, 2023
In complement activation system, although the classical pathway has shown to play a critical role for the pathogenesis of SLE, the role of lectin pathway has remained unknown in the pathogenesis of SLE.
Yuko Asanuma, Kazuhisa Nozawa, Masakazu Matsushita, Makio Kusaoi, Yoshiyuki Abe, Ken Yamaji, Naoto Tamura   +6 more
doaj   +1 more source

The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection [PDF]

, 2012
The complement system plays a key role in host defense against pneumococcal infection. Three different pathways, the classical, alternative and lectin pathways, mediate complement activation.
Ali, Youssif M., Andrew, Peter W., Dudler, Thomas, Endo, Yuichi, Fujita, Teizo, Girija, Umakhanth V., Haleem, Kashif S., Hansen, Soren, Holmskov, Uffe, Kadioglu, Aras, Lynch, Nicholas J., Schwaeble, Wilhelm J., Stahl, Gregory L., Stover, Cordula M., Takahashi, Kazue, Wallis, Russell   +15 more
core   +6 more sources

MASP-1 and MASP-3 Bind Directly to Aspergillus fumigatus and Promote Complement Activation and Phagocytosis

Journal of Innate Immunity, 2021
Activation of the complement system is mediated by the interaction between pathogens and pattern recognition molecules (PRMs); mannose-binding lectin (MBL), ficolins, and collectin-10/-11 from the lectin pathway and C1q from the classical pathway. Lectin
Anne Rosbjerg, Reinhard Würzner, Peter Garred, Mikkel-Ole Skjoedt   +3 more
doaj   +1 more source

Lectin complement pathway and diabetes mellitus in the pathogenesis of membranous nephropathy [PDF]

Folia Medica, 2023
Introduction: Membranous nephropathy (MN) is a glomerulonephritis with growing incidence and its pathogenesis still remains unclear, despite discoveries of many new antigens.
Irina Y. Zdravkova, Eduard E. Tilkiyan, Desislava M. Bozhkova   +2 more
doaj   +3 more sources