Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides. [PDF]
Dürvanger Z+14 more
europepmc +1 more source
Role of phospholipase A2 in the stimulation of sponge cell proliferation by homologous lectin. [PDF]
Friese, K.+8 more
core +1 more source
Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi+2 more
wiley +1 more source
Advances and Challenges in Pluripotent Stem Cell‐Based Whole‐Cell Vaccines for Cancer Treatment
ABSTRACT In recent decades, an unexpected application of pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), as a novel source for whole‐cell vaccines (WCVs) against cancer has attracted attention in the field of tumor immunotherapy.
Guoyue Wan+3 more
wiley +1 more source
Mutual shaping of tumor microbiota and TME. Intratumoral microbiota—comprising diverse bacteria, fungi, viruses, and intracellular organisms—play critical and dynamic roles in shaping the tumor microenvironment (TME). Their spatial and compositional diversity contributes to both intratumoral and intertumoral heterogeneity, influencing immune modulation
Zhifei Gao+9 more
wiley +1 more source
Factors of the Lectin Pathway of Complement Activation and Their Clinical Associations in Neonates [PDF]
Maciej Cedzyński+2 more
openalex +1 more source
The role of the lectin VIP36 in the early secretory pathway
Lectins are of emerging importance for quality control and intracellular transport of glycoproteins in mammalian cells. One of the most prominent lectins involved in intracellular transport is ERGIC-53, which belongs to the family of L-type lectins. ERGIC-53 mediates the ER export of several glycoproteins like cathepsin Z, α1-antitrypsin (α1-AT) or ...
openaire +3 more sources
Recent Advancements in the Treatment of Age‐Related Macular Degeneration
ABSTRACT Age‐related macular degeneration (AMD) is a prevalent cause of visual impairment and blindness among the elderly. AMD can be categorized into two subtypes: “wet” and “dry.” Current treatments for wet AMD mainly involve anti‐vascular endothelial growth factor (VEGF) drugs, and there are three U.S.
Shan Liu+10 more
wiley +1 more source
Reprograming of Gene Expression of Key Inflammatory Signaling Pathways in Human Peripheral Blood Mononuclear Cells by Soybean Lectin and Resveratrol [PDF]
Nilofer Qureshi+4 more
openalex +1 more source
Brain death-induced lung injury is complement dependent, with a primary role for the classical/lectin pathway. [PDF]
van Zanden JE+6 more
europepmc +1 more source