Results 281 to 290 of about 2,474,660 (311)

An Ixodes ricinus Tick Salivary Lectin Pathway Inhibitor Protects Borrelia burgdorferi sensu lato from Human Complement.

Vector Borne and Zoonotic Diseases, 2016
INTRODUCTION We previously identified tick salivary lectin pathway inhibitor (TSLPI) in Ixodes scapularis, a vector for Borrelia burgdorferi sensu stricto (s.s.) in North America. TSLPI is a salivary protein facilitating B. burgdorferi s.s.
A. Wagemakers, J. Coumou, Tim J. Schuijt, Anneke Oei, A. Nijhof, C. van ′t Veer, T. van der Poll, A. Bins, J. Hovius   +8 more
semanticscholar   +1 more source

The mannan-binding-lectin pathway of the innate immune response

Current Opinion in Immunology, 2001
Dramatic progress has been achieved during the past year in our understanding of how the complement system is activated via the mannan-binding-lectin pathway. Surprising discoveries have changed our concepts of the complexes that are formed upon engagement of mannan-binding lectin with its serine proteases.
Gadjeva, M., Thiel, S., Jensenius, J.C.
openaire   +5 more sources

Significance of glomerular activation of the alternative pathway and lectin pathway in lupus nephritis

Lupus, 2011
The objective of the present study was to elucidate the association between glomerular complement depositions belonging to the alternative (AP) and lectin (LP) pathways, and clinical findings of lupus nephritis (LN). Immunofluorescence (IF) was performed on 17 LN patients using antibodies against factor B, factor H, properdin, mannose-binding lectin ...
Hiroyuki Inoshita, Nobuyuki Sato, Yasuhiko Tomino, Seiji Nagamachi, Satoshi Horikoshi, Hiroyuki Ohi, Misao Matsushita, A Toki, Isao Ohsawa, Masaya Ishii, Gaku Kusaba   +10 more
openaire   +3 more sources

An assay for the mannan-binding lectin pathway of complement activation

Journal of Immunological Methods, 2001
The mannan-binding lectin (MBL) pathway of complement activation has been established as the third pathway of complement activation. MBL is a carbohydrate-binding serum protein, which circulates in complex with serine proteases known as mannan-binding lectin associated serine proteases (MASPs).
Petersen, Steen Vang, Thiel, S, Jensen, L, Steffensen, R, Jensenius, J C   +4 more
openaire   +5 more sources

The Initiation Complexes of the Classical and Lectin Pathways

2006
Various antigen structures initiate the classical and the lectin pathways of complement activation. Multidomain modular proteases (C1r, C1s and MASPs) are involved in the initiation complexes of both pathways. Despite the identical domain organization of these serine proteases there are differences in their specificities and functions.
Géza Ambrus, Péter Závodszky, Zsolt Lőrincz, Péter Gál   +3 more
openaire   +2 more sources

The lectin pathway

Research in Immunology, 1996
T. Fujita, M. Matsushita
openaire   +3 more sources

The lectin pathway in IgA nephropathy

Molecular Immunology, 2007
R. Kolka, M. Böðvarsson, Steffen Thiel, Helgi Valdimarsson, S.L. Sigurðardottir, Th. Jonsson, S. Harðarson   +6 more
openaire   +2 more sources

Mechanism of the activation of the lectin pathway

Molecular Immunology, 2011
Andrea Kocsis, Péter Gál, József Dobó, Péter Závodszky, Gábor Pál, Katalin Szilágyi, Dávid Héja   +6 more
openaire   +2 more sources

Lectins of ERAD Pathway: F-Box Proteins and M-Type Lectins

2012
Glycoprotein folding and degradation in endoplasmic reticulum (ER) is mediated by ER quality control system. Quality control in ER ensures that only properly folded proteins are retained in the cell through mechanisms that recognize and discard misfolded or unassembled proteins in a process called endoplasmic reticulum-associated degradation (ERAD ...
openaire   +2 more sources

Application of Lectin Microarrays for Biomarker Discovery

ChemistryOpen, 2020
Airong Qian, Airong Qian
exaly