Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction. [PDF]
BackgroundChronic Lung Allograft Dysfunction (CLAD) is the main limitation to long-term survival after lung transplantation. Although CLAD is usually not responsive to treatment, earlier identification may improve treatment prospects.MethodsIn a nested ...
Ardehali, Abbas+15 more
core +2 more sources
High glucose disrupts oligosaccharide recognition function via competitive inhibition : a potential mechanism for immune dysregulation in diabetes mellitus [PDF]
Diabetic complications include infection and cardiovascular disease. Within the immune system, host-pathogen and regulatory host-host interactions operate through binding of oligosaccharides by C-type lectin.
Ahmed+54 more
core +1 more source
Pattern recognition receptors in antifungal immunity [PDF]
We thank the Wellcome Trust for funding this study.Peer reviewedPublisher ...
Brown, Gordon D+2 more
core +2 more sources
Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei [PDF]
BACKGROUND Vacuolar H-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles.
Hide, G+4 more
core +2 more sources
Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti+3 more
core +5 more sources
Glycobiology of the olfactory system [PDF]
The olfactory system is a highly plastic region of the nervous system. Continuous remodeling of neuronal circuits in the olfactory bulb takes place throughout life as a result of constant turnover of primary sensory olfactory neurons in the periphery ...
Plendl, J., Sinowatz, Fred
core +1 more source
Sensitive detection of ultra-weak adhesion states of vesicles by interferometric microscopy [PDF]
We have used an original analysis of reflection interference contrast microscopy (RICM) to detect an ultra-weak specific interaction between a glycolipid vesicle and a lectin-coated substrate. The membrane height fluctuations in the contact zone are observed with a high illumination aperture; the membrane profile and the membrane-substrate distance ...
arxiv +1 more source
The complement lectin pathway after cardiac arrest [PDF]
AbstractThe lectin pathway (LP) of the complement system may initiate inflammatory reactions when body tissue is altered. We aimed to investigate the levels of the LP proteins in out‐of‐hospital cardiac arrest patients, and to compare these with healthy individuals.
S. F. Haugaard+5 more
openaire +3 more sources
PDGFB as a vascular normalization agent in an ovarian cancer model treated with a gamma-secretase inhibitor [PDF]
Ovarian cancer is the fifth leading cause of cancer-related deaths in women. In the past 20 years, the canonical types of drugs used to treat ovarian cancer have not been replaced and the survival rates have not changed.
Abramovich, Dalhia Nurit+7 more
core +1 more source
Thiol isomerase ERp57 targets and modulates the lectin pathway of complement activation. [PDF]
ER protein 57 (ERp57), a thiol isomerase secreted from vascular cells, is essential for complete thrombus formation in vivo, but other extracellular ERp57 functions remain unexplored.
Eriksson O+6 more
europepmc +2 more sources