Results 81 to 90 of about 2,474,660 (311)

Collectin-11/MASP Complex Formation Triggers Activation of the Lectin Complement Pathway - The Fifth Lectin Pathway Initiation Complex [PDF]

Journal of Innate Immunity, 2012
Collectins and ficolins are important in the clearance of endogenous and exogenous danger materials. A new human collectin-11 was recently identified in low concentration in serum in complex with mannose-binding lectin (MBL)/ficolin-associated serine proteases. Collectin-11 binds to carbohydrate residues present on various microorganisms.
Ma, Ying Jie, Skjoedt, Mikkel-Ole, Garred, Peter   +2 more
openaire   +4 more sources

Investigation on the Influence of Protein Corona and Platelet Adhesion on Storage Bag Surface on the Platelet Storage Lesion

Advanced Healthcare Materials, EarlyView.
Platelet quality deteriorates during storage due to protein and platelet adhesion to current bag materials. Here, polymer coatings are identified that reduce adhesion and translated them to mini‐storage bags. Platelet quality are not impacted, despite significantly reducing adhesion.
Nicolas Pereyra, Kai Yu, Jason Rogalski, Taylor Olivia Da Silva, Parisa Golesorkhi, Madeleine Goldstein, Dana V. Devine, Jayachandran N. Kizhakkedathu   +7 more
wiley   +1 more source

Machine‐Learning‐Aided Advanced Electrochemical Biosensors

Advanced Materials, EarlyView.
Electrochemical biosensors are highly sensitive, portable, and versatile. Advanced nanomaterials enhance their performance, while machine learning (ML) improves data analysis, minimizes interference, and optimizes sensor design. Despite progress in both fields, their combined potential in diagnostics remains underexplored.
Andrei Bocan, Roozbeh Siavash Moakhar, Carolina del Real Mata, Max Petkun, Tristan De Iure‐Grimmel, Sripadh Guptha Yedire, Hamed Shieh, Arash Khorrami Jahromi, Sahar Sadat Mahshid, Sara Mahshid   +9 more
wiley   +1 more source

A Highly Adaptable Hydrogen Bond Re‐Orientation (HyBRO) Strategy for Multiscale Vasculature Fabrication

Advanced Materials, EarlyView.
A novel hydrogen bond re‐orientation (HyBRO) strategy enables three‐dimensional (3D) printing of vascular microchannel networks with high accuracy. By switching sacrificial material interactions with nonsolvents, HyBRO prevents swelling and deformation, enabling accurate hierarchical channels spanning a tenfold size range.
Zhencheng Liao, Yu Liu, Chonghao Chen, Iek Man Lei, Lei Dong, Chunming Wang   +5 more
wiley   +1 more source

Lectin Pathway Components And Its Transfer From Blood To Cerebrospinal Fluid

Revista Cubana de Investigaciones Biomédicas, 2019
Introduction: Defining mechanisms governing the diffusion from blood to cerebrospinal fluid is central to understanding immune function in the central nervous system. OBJECTIVE.
Alejandro Ramos-Robledo, Christian Meijides Mejías, José Alejandro Rodríguez Pérez, Alejandro Mirabal Viel, Vanessa Pérez del Vallín, Alberto Juan Dorta Contreras   +5 more
doaj  

Lectin Complement Pathway Activation is Associated with Massive Proteinuria in PLA2R-Positive Membranous Nephropathy: A Retrospective Study

International Journal of General Medicine, 2023
Jiayi Li,1,2 Jiao Zhang,2 Xu Wang,2 Xumin Zheng,2 Hongmei Gao,2 Shimin Jiang,2 Wenge Li1,2 1Department of Nephrology, Peking University China-Japan Friendship School of Clinical Medicine, Beijing, People’s Republic of China; 2Department of ...
Li J, Zhang J, Wang X, Zheng X, Gao H, Jiang S, Li W   +6 more
doaj  

Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury

Frontiers in Immunology, 2019
Proteinuria is an adverse prognostic feature in renal diseases. In proteinuric nephropathies, filtered proteins exert an injurious effect on the renal tubulointerstitium, resulting in inflammation and fibrosis.
Samy Alghadban, Samy Alghadban, Hany I. Kenawy, Hany I. Kenawy, Thomas Dudler, Wilhelm J. Schwaeble, Wilhelm J. Schwaeble, Nigel J. Brunskill, Nigel J. Brunskill   +8 more
doaj   +1 more source

MASP-1 induces a unique cytokine pattern in endothelial cells: a novel link between complement system and neutrophil granulocytes. [PDF]

PLoS ONE, 2014
Microbial infection urges prompt intervention by the immune system. The complement cascade and neutrophil granulocytes are the predominant contributors to this immediate anti-microbial action.
Péter K Jani, Erika Kajdácsi, Márton Megyeri, József Dobó, Zoltán Doleschall, Krisztina Futosi, Csaba I Tímár, Attila Mócsai, Veronika Makó, Péter Gál, László Cervenak   +10 more
doaj   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
wiley   +1 more source