Results 61 to 70 of about 3,190,451 (315)

The complement lectin pathway after cardiac arrest [PDF]

open access: yesScandinavian Journal of Immunology, 2018
AbstractThe lectin pathway (LP) of the complement system may initiate inflammatory reactions when body tissue is altered. We aimed to investigate the levels of the LP proteins in out‐of‐hospital cardiac arrest patients, and to compare these with healthy individuals.
S. F. Haugaard   +5 more
openaire   +3 more sources

Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum.

open access: yesPLoS Pathogens, 2019
Ecotin is a serine protease inhibitor produced by hundreds of microbial species, including pathogens. Here we show, that ecotin orthologs from Escherichia coli, Yersinia pestis, Pseudomonas aeruginosa and Leishmania major are potent inhibitors of MASP-1 ...
Zoltán Attila Nagy   +10 more
doaj   +1 more source

Ricin trafficking in plant and mammalian cells [PDF]

open access: yes, 2011
Ricin is a heterodimeric plant protein that is potently toxic to mammalian and many other eukaryotic cells. It is synthesized and stored in the endosperm cells of maturing Ricinus communis seeds (castor beans).
Lord, Mike, Spooner, Robert A.
core   +2 more sources

Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19

open access: yesFrontiers in Immunology, 2022
Complement plays an important role in the direct defense to pathogens, but can also activate immune cells and the release of pro-inflammatory cytokines. However, in critically ill patients with COVID-19 the immune system is inadequately activated leading
Janina Niederreiter   +7 more
semanticscholar   +1 more source

Research advances on plant lectin receptor-like kinases in abiotic stress response

open access: yesGuangxi Zhiwu, 2023
Plants are exposed to various stress during their growth and development, and abiotic stress is one of the most significant factors. Receptor-like kinases (RLKs) are widely present in plants that can quickly and effectively respond to stress, ultimately ...
Menglong WANG   +3 more
doaj   +1 more source

MASP-1 and MASP-3 Bind Directly to Aspergillus fumigatus and Promote Complement Activation and Phagocytosis

open access: yesJournal of Innate Immunity, 2021
Activation of the complement system is mediated by the interaction between pathogens and pattern recognition molecules (PRMs); mannose-binding lectin (MBL), ficolins, and collectin-10/-11 from the lectin pathway and C1q from the classical pathway. Lectin
Anne Rosbjerg   +3 more
doaj   +1 more source

Identification of the Plasticity-Relevant Fucose-α(1−2)-Galactose Proteome from the Mouse Olfactory Bulb [PDF]

open access: yes, 2009
Fucose-α(1−2)-galactose [Fucα(1−2)Gal] sugars have been implicated in the molecular mechanisms that underlie neuronal development, learning, and memory. However, an understanding of their precise roles has been hampered by a lack of information regarding
Domino, Steven E.   +5 more
core   +4 more sources

Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]

open access: yes, 2017
Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti   +3 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Role of the lectin complement pathway in kidney transplantation [PDF]

open access: yesImmunobiology, 2016
In the last 15 years two major advances in the role of complement in the kidney transplant have come about. The first is that ischaemia reperfusion injury and its profound effect on transplant outcome is dependent on the terminal product of complement activation, C5b-9. The second key observation relates to the function of the small biologically active
Farrar, Conrad A.   +2 more
openaire   +4 more sources

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