Results 211 to 220 of about 24,283,245 (285)

Mutations in the N-glycan branching enzyme MGAT1 promote invasiveness and EGF-stimulated proliferation and adhesion in neuroblastoma cells. [PDF]

PLoS One
Hall MK, Walker LJ, Messer AR, Schwalbe RA.   +3 more
europepmc   +1 more source

Lactate‐Responsive Glycogen Dynamics Are Associated With Bull Sperm Motility and Fertilization Under Glucose‐Limited Conditions

Andrology, EarlyView.
ABSTRACT Background Mammalian sperm need to undergo hyperactivation, capacitation, and acrosome reaction to achieve fertilization competence. However, the female reproductive tract presents contrasting metabolic environments. The uterus is glucose‐rich, and the oviduct is lactate‐rich and glucose‐limited.
Md Faizul Hossain Miraz, Takahiro Yamanaka, Takashi Umehara, Shahrina Akter, Wambugu Enoc Njoroge, Masayuki Shimada   +5 more
wiley   +1 more source

Versatile Glycan Probes for Multiplatform Investigation of Glycan Interactions with Proteins, Viruses, and Cells. [PDF]

Nat Commun
Yu J, Decout A, Yang J, Di Maio A, Chai W, Turnbull WB, Stehle T, Sacks SH, Peacock TP, Iqbal M, Feizi T, Liu Y.   +11 more
europepmc   +1 more source

Morphological and Morphometric Characterisation of Selected Camarodont Sea Urchin (Echinoidea: Camarodonta) Pedicellariae (Paracentrotus lividus, Psammechinus miliaris and Echinus esculentus)

Acta Zoologica, EarlyView.
ABSTRACT Pedicellariae are small appendages on the surface of the echinoid test, involved in defence, cleaning, and locomotion. Pedicellariae in three species of camarodont sea urchins common in UK waters (Paracentrotus lividus [Lamarck, 1816], Psammechinus miliaris [P.L.S Müller, 1771] and Echinus esculentus [Linnaeus, 1758]) are the focus of this ...
H. C. Reinardy, R. Marton, C. Allen, E. Mitchell, L. Brunner, A. D. Hughes, R. A. Jenner   +6 more
wiley   +1 more source

Sponge Galectins: Structure, Evolution, and Function. [PDF]

ACS Omega
Sousa ARO, Ferreira da Ponte JAD, Sampaio AH, Nagano CS, Carneiro RF.   +4 more
europepmc   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

Brain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu, Yoshiki Takai, Naoya Yamazaki, Sarah Brandl, Katharina M. Mair, Thibault Bouderlique, Maria Eleni Kastriti, Igor Adameyko, Romana Höftberger, Markus Reindl, Jan Bauer, Monika Bradl   +11 more
wiley   +1 more source

Fermentation as a Lever to Enhance Legume Proteins: From Antinutritional Factors to Improved Quality. [PDF]

Molecules
Smaoui S, Moin A, Chtourou H, Ben Braïek O, Fourati M, Varzakas T.   +5 more
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Transcriptomic data and editing rate quantification of apple knock-out transgenic lines for a family of 17 amaranthin-like lectins. [PDF]

Data Brief
Frantz A, Bodelot A, Dousset N, Ravon E, Heintz C, Vergne E, Degrave A, Gaucher M.   +7 more
europepmc   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source