Results 231 to 240 of about 24,283,245 (285)

Lipid nanoparticle formulations including stereochemically defined glycomacromolecules for delivery of saRNA. [PDF]

Chem Sci
Becker J, Dias-Barbieri B, Shattock RJ, Becer CR.   +3 more
europepmc   +1 more source

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

Altering the carbohydrate-binding specificity of the legume lectin FRIL through structure-guided engineering. [PDF]

Nat Commun
Liu YM, Nguyen HTV, Chen X, Shahed-Al-Mahmud M, Chen TH, Liao KS, Lo JM, Kan TC, Ren CT, Ma C.   +9 more
europepmc   +1 more source

Serum Agalactosyl IgG Predicts Hepatocellular Carcinoma and All‐Cause Mortality After SVR in Advanced Chronic Hepatitis C

Hepatology Research, EarlyView.
ABSTRACT Background and Aims Patients with chronic hepatitis C and advanced fibrosis remain at substantial risk of hepatocellular carcinoma (HCC) and non‐liver–related death even after sustained virological response (SVR) to direct‐acting antivirals (DAA).
Daisuke Sakon, Jumpei Kondo, Yuki Tahata, Hayato Hikita, Maki Iwaisako, Muya Matsumoto, Asuka Ogata, Shinji Takamatsu, Yasutoshi Nozaki, Naruyasu Kakita, Hisashi Ishida, Fumihiko Nakanishi, Yuichi Yoshida, Masanori Nakahara, Kazuho Imanaka, Mitsuru Sakakibara, Takayuki Yakushijin, Tetsuo Takehara, Takahiro Kodama, Eiji Miyoshi   +19 more
wiley   +1 more source

Overexpression of <i>OsMBL1</i> Is Associated with Changes in Flavonoid Biosynthesis and Antioxidant Capacity in Rice. [PDF]

Biology (Basel)
Zhu M, Zhan Z, Fei F, Cai Y, Ding M, Ding H.   +5 more
europepmc   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

The C-type lectin AcCTL5 from <i>Apis cerana</i> mediates anti-<i>Nosema ceranae</i> defense via agglutination and hemolymph melanization. [PDF]

Virulence
Li D, Huang T, Hai Q, Ma Q, Liu X, Dang X, Ma Z, Xu J, Zhou Z.   +8 more
europepmc   +1 more source

Integrative transcriptomic and machine learning approaches reveal candidate genes for silk and venom production in Bibionomorpha (Diptera)

Insect Molecular Biology, EarlyView.
Multi‐species transcriptomics and deep learning identified candidate genes associated with silk and venom production in Bibionomorpha. Venom‐associated genes were enriched in proteases, inhibitors and pore‐forming proteins, whereas silk‐related genes showed chitin‐binding and peritrophin domains. Integrating co‐expression networks, machine learning and
Daniel Kenji Matuo, João Alfredo Teodoro, Danilo T. Amaral   +2 more
wiley   +1 more source

GlycoChat Uncovers Glycan-Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer. [PDF]

Adv Sci (Weinh)
Anh DXT, Keisham S, Burramsetty A, Oinam L, Kumano K, Kuno A, Shimomura O, Oda T, Tateno H.   +8 more
europepmc   +1 more source

Myo1g Mediates NKR‐P1C Expression in Primary Mouse NK Cells and Participates in Cytotoxicity

Immunology, EarlyView.
In this study we analysed the participation of Myosin 1g in the development and functions of murine natural killer (NK) cells; we found that Myosin 1g is expressed in murine‐activated primary NK cells from the spleen. Additionally, in the absence of Myosin 1g, correlates with a reduced expression of NKR‐P1C but not of CD49b or NKp46.
Héctor Romero‐Ramírez, Vania Aminta Zuleica López‐Esparza, Mariana Flores‐Castelán, Leopoldo Santos‐Argumedo   +3 more
wiley   +1 more source