Results 301 to 310 of about 1,772,176 (315)

C-Type Lectin Receptors in Antifungal Immunity

2020
Most fungal species are harmless to humans and some exist as commensals on mucocutaneous surfaces. Yet many fungi are opportunistic pathogens, causing life-threatening invasive infections when the immune system becomes compromised. The fungal cell wall contains conserved pathogen-associated molecular patterns (PAMPs), which allow the immune system to ...
Christina Nikolakopoulou, Janet A. Willment, Janet A. Willment, Gordon D. Brown, Gordon D. Brown   +4 more
openaire   +3 more sources

A C‐type lectin with a single carbohydrate‐recognition domain involved in the innate immune response of Tribolium castaneum

Insect molecular biology (Print), 2019
C‐type lectins are one of the pattern‐recognition proteins involved in innate immunity in invertebrates. Although there are 16 C‐type lectin genes that have been identified in the genome of Tribolium castaneum, their functions and mechanisms in innate ...
J. Bi, Fan Feng, J. Li, Jinjuan Mao, M. Ning, Xiaowen Song, Jianyuan Xie, Jing Tang, Bin Li   +8 more
semanticscholar   +1 more source

Role of C-Type Lectins in Mycobacterial Infections

Current Drug Targets, 2008
Worldwide clinical cases due to multi drug- and extensively drug-resistant strains of Mycobacterium tuberculosis (M.tb) are increasing making the need for new therapies more critical than ever. A major obstacle for designing new drugs to treat mycobacterial infections is our limited knowledge of the interface between the bacillus (especially M.tb) and ...
Jordi B. Torrelles, Azad Ak, Schlesinger Ls, Henning Ln, Carlson Tk   +4 more
openaire   +3 more sources

C-Type Lectin Family: Overview [PDF]

, 2014
Members of the C-type lectin family of glycan-binding receptors in animals contain modular carbohydrate recognition domains (CRDs) that form a subset of a larger structural class of protein modules designated C-type lectin-like domains. Two broad categories of C-type CRDs bind either mannose and related sugars or galactose and related sugars at the Ca ...
Maureen E. Taylor, Kurt Drickamer
openaire   +1 more source

Emerging Groups of C-Type Lectins [PDF]

, 2012
Layilin, a ~55-kDa lectin, is a widely expressed integral membrane hyaluronan receptor, originally identified as a binding partner of talin located in membrane ruffles. It is recruited to membrane ruffles in cells induced to migrate in in vitro wounding experiments and in peripheral ruffles in spreading cells.
openaire   +1 more source

A Family of C-Type Lectins in Manduca sexta

2001
Insects have a rapid and effective immune system against microbial infections (Gillespie et al., 1997) that shares common characteristics with the innate immune system of vertebrates. It also consists of humoral and cellular responses. In the cellular responses such as phagocytosis, nodule formation and encapsulation, hemocytes play important roles. In
Xiao-Qiang Yu, Michael R. Kanost
openaire   +3 more sources

C-type lectins: their network and roles in pathogen recognition and immunity

Histochemistry and Cell Biology, 2017
S. Mayer, M. Raulf, B. Lepenies
semanticscholar   +1 more source

Classification of C‐Type Lectins and Recognition of Pathogens

Microbiology and Immunology
ABSTRACTC‐type lectins are calcium‐dependent glycan‐binding proteins that play key roles in the innate immune response by recognizing pathogens. Soluble C‐type lectins agglutinate and neutralize pathogens, activate the complement system, and promote pathogen clearance via opsonization.
openaire   +2 more sources

DC-SIGN, DC-SIGNR and LSECtin: C-Type Lectins for Infection

International Reviews of Immunology, 2014
Feng Zhang, S. Ren, Y. Zuo
semanticscholar   +1 more source

C-Type Lectin (C-Type Lectin Receptor)

2022
openaire   +1 more source