Results 61 to 70 of about 43,176 (288)

C-type Lectin Receptors for Tumor Eradication: Future Directions [PDF]

open access: yesCancers, 2011
Dendritic cells are key regulators in directing immune responses and therefore are under extensive research for the induction of anti-tumor responses. DCs express a large array of receptors by which they scan their surroundings for recognition and uptake of pathogens.
Streng-Ouwehand, Ingeborg   +2 more
openaire   +4 more sources

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

A new player in the game: platelet-derived extracellular vesicles in dengue hemorrhagic fever

open access: yesPlatelets, 2020
Thrombocytopenia and vascular leakage are clinical hallmarks in dengue hemorrhagic fever. Sung et al. present a new mechanism where platelet-derived extracellular vesicles participate in increasing vascular permeability during dengue virus infection in ...
Marisol Perez-Toledo   +1 more
doaj   +1 more source

Taxonomic Distribution and Molecular Evolution of Mytilectins

open access: yesMarine Drugs, 2023
R-type lectins are a widespread group of sugar-binding proteins found in nearly all domains of life, characterized by the presence of a carbohydrate-binding domain that adopts a β-trefoil fold.
Marco Gerdol   +6 more
doaj   +1 more source

C-type lectins in immunity to Mycobacterium tuberculosis

open access: yesFrontiers in Bioscience, 2011
Tuberculosis (TB) remains one of the leading causes of death due to a single infectious agent, Mycobacterium tuberculosis, with nearly 2 million deaths per year (1). Most individuals exposed to the bacillus develop a nonpathological form, latent TB, with only a small minority (5 to 10%) developing active disease.
Antoine, Tanne, Olivier, Neyrolles
openaire   +2 more sources

“Sweet Talk”: Closing in on C Type Lectin Signaling [PDF]

open access: yesImmunity, 2005
C type lectins recognize pathogens by binding to pathogen-specific carbohydrate residues. The finding reported by Rogers et al. (2005) in this issue of Immunity, that ligand binding by the C type lectin Dectin-1 leads to recruitment of the tyrosine kinase Syk and is critical to subsequent cytokine production by the cell, will surely inspire further ...
Meyer-Wentrup, F.   +3 more
openaire   +5 more sources

C-type lectins do not act as functional receptors for filovirus entry into cells [PDF]

open access: yes, 2010
Cellular C-type lectins have been reported to facilitate filovirus infection by binding to glycans on filovirus glycoprotein (GP). However, it is not clearly known whether interaction between C-type lectins and GP mediates all the steps of virus entry (i.
Keita Matsuno   +15 more
core   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

open access: yesAdvanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer   +17 more
wiley   +1 more source

Functional comparison of the mouse DC‐SIGN, SIGNR1, SIGNR3 and Langerin, C‐type lectins [PDF]

open access: yes, 2004
The mouse (m) DC-SIGN family consists of several homologous type II transmembrane proteins located in close proximity on chromosome 8 and having a single carboxyl terminal carbohydrate recognition domain.
박채규
core   +3 more sources

Variation of Neisseria gonorrhoeae lipooligosaccharide directs dendritic cell-induced T helper responses. [PDF]

open access: yesPLoS Pathogens, 2009
Gonorrhea is one of the most prevalent sexually transmitted diseases in the world. A naturally occurring variation of the terminal carbohydrates on the lipooligosaccharide (LOS) molecule correlates with altered disease states.
Sandra J van Vliet   +8 more
doaj   +1 more source

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