Results 61 to 70 of about 67,545 (209)

A new player in the game: platelet-derived extracellular vesicles in dengue hemorrhagic fever

open access: yesPlatelets, 2020
Thrombocytopenia and vascular leakage are clinical hallmarks in dengue hemorrhagic fever. Sung et al. present a new mechanism where platelet-derived extracellular vesicles participate in increasing vascular permeability during dengue virus infection in ...
Marisol Perez-Toledo   +1 more
doaj   +1 more source

Taxonomic Distribution and Molecular Evolution of Mytilectins

open access: yesMarine Drugs, 2023
R-type lectins are a widespread group of sugar-binding proteins found in nearly all domains of life, characterized by the presence of a carbohydrate-binding domain that adopts a β-trefoil fold.
Marco Gerdol   +6 more
doaj   +1 more source

Developments in plant breeding for improved nutritional quality of soya beans II. Anti-nutritional factors [PDF]

open access: yes, 2000
Nutritional value of most plant materials is limited by the presence of numerous naturally occurring compounds which interfere with nutrient digestion and absorption.
Clarke, E, Wiseman, J
core   +1 more source

Tetranectin, a trimeric plasminogen‐binding C‐type lectin [PDF]

open access: yesProtein Science, 1997
AbstractTetranectin, a plasminogen‐binding protein belonging to the family of C‐type lectins, was expressed in E. coli and converted to its native form by in vitro refolding and proteolytic processing. Recombinant tetranectin—as well as natural tetranectin from human plasma—was shown by chemical cross‐linking analysis and SDS‐PAGE to be a homo‐trimer ...
Holtet, Thor L.   +4 more
openaire   +3 more sources

Variation of Neisseria gonorrhoeae lipooligosaccharide directs dendritic cell-induced T helper responses. [PDF]

open access: yesPLoS Pathogens, 2009
Gonorrhea is one of the most prevalent sexually transmitted diseases in the world. A naturally occurring variation of the terminal carbohydrates on the lipooligosaccharide (LOS) molecule correlates with altered disease states.
Sandra J van Vliet   +8 more
doaj   +1 more source

Platelets and galectins [PDF]

open access: yes, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

Syk-coupled C-type lectins in immunity

open access: yesTrends in Immunology, 2011
The Syk-coupled C-type lectin receptor Dectin-1 was the first non-Toll like receptor described that could mediate its own intracellular signalling. It was initially identified as important for the innate recognition of and response to fungal pathogens but later studies revealed that it is also involved in triggering adaptive immune responses.
Kerrigan, Ann M., Brown, Gordon D.
openaire   +2 more sources

Targeting C-Type Lectin Receptors for Cancer Immunity [PDF]

open access: yesFrontiers in Immunology, 2015
C-type lectin receptors (CLRs) are a large family of soluble and trans-membrane pattern recognition receptors that are widely and primarily expressed on myeloid cells. CLRs are important for cell-cell communication and host defense against pathogens through the recognition of specific carbohydrate structures. Similar to a family of Toll-like receptors,
Huimin eYan   +6 more
openaire   +3 more sources

Novel Urinary Glycan Biomarkers Predict Cardiovascular Events in Patients With Type 2 Diabetes: A Multicenter Prospective Study With 5-Year Follow Up (U-CARE Study 2)

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Although various biomarkers predict cardiovascular event (CVE) in patients with diabetes, the relationship of urinary glycan profile with CVE in patients with diabetes remains unclear.Methods: Among 680 patients with type 2 diabetes, we ...
Koki Mise   +24 more
doaj   +1 more source

Protein-carbohydrate interactions during fertilization [PDF]

open access: yes, 1998
Interaction between gametes during fertilization is at least in part regulated by carbohydrate moieties of the zona pellucida (ZP) and carbohydrate binding proteins of the sperm surface. This review focuses on the protein-carbohydrate interactions during
Kolle, S., Plendl, J., Sinowatz, Fred
core   +1 more source

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