Results 141 to 150 of about 64,311 (254)

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

A glycosaminoglycan microarray identifies galectin-4 binding to sulfated glycosaminoglycans. [PDF]

Biochem Biophys Rep
Sano K, Nagatomo M, Shigematsu K, Yamasaki K, Anh DXT, Shibuya A, Otsuka Y, Minamisawa T, Tateno H.   +8 more
europepmc   +1 more source

The Crude Venom of the Whitetail Lancehead, Bothrops leucurus, and Two of Its Enzymatic Components Are Selectively Cytotoxic for Glioma Cells In Vitro

Journal of Applied Toxicology, EarlyView.
ABSTRACT Malignant glioma is the most common primary brain tumor, and glioblastoma multiforme (GBM) remains its most aggressive and incurable form. Snake venoms contain bioactive compounds with promising antitumoral properties against several cancer types.
M. O. H. V. Rosário, T. M. Fucase, P. J. Spencer, J. M. Sciani, J. Clarêncio, G. Rádis‐Baptista, L. L. Casais‐e‐Silva, R. S. El‐Bachá   +7 more
wiley   +1 more source

A N-Acetyl-D-Glucosamine-Binding C-Type Lectin in the Cutaneous Mucus of Chub Mackerel, Scomber japonicus, Agglutinates Pathogenic Bacteria. [PDF]

Microbiol Immunol
Tsutsui S, Kunisaki T, Izawa T, Nakamura O.   +3 more
europepmc   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Single-Cell Glycomics of the Pancreatic Tumor Microenvironment: Technologies, Glyco-Immune Checkpoints, and Tumor-Immune Communication. [PDF]

Adv Biol (Weinh)
Anh DXT, Tateno H.
europepmc   +1 more source

Anti‐Erythrocyte Antibody Formation in Individuals With and Without Known Sensitisation Pathways Reflecting Indications for Extended Immunohaematology Screening

Journal of Clinical Laboratory Analysis, EarlyView.
– The yearly incidence of anti‐red blood cell antibodies stratified by participant groups and temporal evolution. – Overall significance p = 3.756 × 10−29. ABSTRACT Background Blood transfusion therapies are of vital importance for many patient groups.
Milanka Milosavić, Marko Lilić, Gordana Guzijan, Dušan Vučetić   +3 more
wiley   +1 more source

Lectin-Micropatterned Biointerfaces Regulate Cytoskeletal Organization and Viscoelastic Phenotypes of Bladder Cancer Cells. [PDF]

ACS Omega
Zemła J, Śmiałek-Bartyzel J, Brzuchacz B, Lekka M.   +3 more
europepmc   +1 more source

Interactions between listeriae and lectins

, 2000
Interactions between members of the genus Listeria and lectins are described. L. monocytogenes was shown to be heterogenous with respect to agglutination by lectins. L.
Bui Phuong, Thuan, Calderón de la Barca A.M., Doyle R.J., Galsworthy S.B., Buck G.   +4 more
core  

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source