Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease [PDF]
Nature Communications, 2023 Pulmonary hypertension worsens outcome in left heart disease. Stiffening of the pulmonary artery may drive this pathology by increasing right ventricular dysfunction and lung vascular remodeling.
Mariya M. Kucherenko +19 more
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Hemodynamic Definitions, Phenotypes, Pathophysiology, and Evaluation of Pulmonary Hypertension Related to Left Heart Disease [PDF]
Journal of Cardiovascular Development and DiseasePulmonary hypertension (PH) can develop from multiple etiologic mechanisms and disease states. Of all such conditions, left-sided heart disease (LHD) is commonly understood to be the most common etiology or mechanism.
Elizabeth C. Ghandakly +2 more
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An updated meta‐analysis of hemodynamics markers of prognosis in patients with pulmonary hypertension due to left heart disease [PDF]
Pulmonary Circulation, 2022 Pulmonary hypertension (PH) is associated with a poor prognosis in left heart disease (LHD). We sought to provide an updated analysis on the association of hemodynamic variables, such as pulmonary vascular resistance (PVR), pulmonary artery compliance ...
Claudia Baratto +8 more
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Pathogenesis of pulmonary hypertension caused by left heart disease [PDF]
Frontiers in Cardiovascular Medicine, 2023 Pulmonary hypertension has high disability and mortality rates. Among them, pulmonary hypertension caused by left heart disease (PH-LHD) is the most common type.
Mingzhu Xiao +4 more
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Metformin in Pulmonary Hypertension in Left Heart Disease [PDF]
Frontiers in Medicine, 2020 Metformin is ubiquitously used in the management of Type II Diabetes Mellitus (DMII). Over the years, our growing knowledge of its therapeutic potential has broadened its use to the treatment of infertility in polycystic ovarian syndrome, gestational ...
Vinaya Mulkareddy +6 more
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Echocardiographic Grading of Right Ventricular Afterload in Left Heart Disease: Relation to Right Ventricular Function, Pulsatile and Resistant Load, and Outcome [PDF]
Pulmonary CirculationThe hemodynamic definitions of pulmonary hypertension consider resistive loading (pulmonary vascular resistance [PVR]), but there are increasing evidence that pulsatile loading (pulmonary artery compliance [PAC]) has functional and prognostic importance.
Odd Bech‐Hanssen +4 more
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Pulmonary hypertension in left heart disease [PDF]
Archives of Medical Science, 2018 Pulmonary hypertension in left heart disease (PH-LHD) is the most prevalent form of PH. It is classified as group 2 PH as per WHO classification. As the prevalence of left heart disease such as congestive heart failure is increasing, the number of ...
Pratishtha Mehra +6 more
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Under pressure: pulmonary hypertension associated with left heart disease [PDF]
European Respiratory Review, 2015 Pulmonary hypertension (PH) associated with left heart disease (PH-LHD) is the most common type of PH, but its natural history is not well understood. PH-LHD is diagnosed by right heart catheterisation with a mean pulmonary arterial pressure ≥25 mmHg and
Harrison W. Farber, Simon Gibbs
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Isolated Major Aortopulmonary Collateral as the Sole Pulmonary Blood Supply to an Entire Lung Segment [PDF]
Case Reports in Cardiology, 2017 Congenital systemic-to-pulmonary collateral arteries or major aortopulmonary collaterals are associated with cyanotic congenital heart disease with decreased pulmonary blood flow.
Hannah S. Kim +2 more
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Pathophysiology and Diagnosis of Pulmonary Hypertension Due to Left Heart Disease [PDF]
Frontiers in Medicine, 2018 Pulmonary hypertension due to left heart disease (PH-LHD) is the most common type of pulmonary hypertension, although an accurate prevalence is challenging.
Athanasios Charalampopoulos +7 more
doaj +2 more sources