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Use of Frogs as a Model to Study the Etiology of HLHS

Journal of Cardiovascular Development and Disease, 2023
A frog is a classical model organism used to uncover processes and regulations of early vertebrate development, including heart development. Recently, we showed that a frog also represents a useful model to study a rare human congenital heart disease ...
Shuyi Nie
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Left atrial volume index is superior to left atrial diameter index in relation to coronary heart disease in hypertension patients with preserved left ventricular ejection fraction

Clinical and Experimental Hypertension, 2020
Objective: Research hypothesis is that left atrial (LA) volume index is superior to LA diameter index for coronary heart disease and LA volume index is important to refine risk stratification.
Ming Fu, Dan Zhou, Songtao Tang, Yingling Zhou, Yingqing Feng, Qingshan Geng   +5 more
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Right Ventricular Function in Left Heart Disease [PDF]

Seminars in Cardiothoracic and Vascular Anesthesia, 2018
Right ventricular (RV) function is an independent prognostic factor for short- and long-term outcomes in cardiac surgical patients. Patients with mitral valve (MV) disease are at increased risk of RV dysfunction before and after MV operations. Yet RV function is not part of criteria for decision making or risk stratification in this setting.
J. Mauricio Del Rio, Loreta Grecu, Alina Nicoara   +2 more
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The pathophysiology of pulmonary hypertension in left heart disease [PDF]

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2015
Pulmonary hypertension (PH) is characterized by elevated pulmonary arterial pressure leading to right-sided heart failure and can arise from a wide range of etiologies. The most common cause of PH, termed Group 2 PH, is left-sided heart failure and is commonly known as pulmonary hypertension with left heart disease (PH-LHD).
Siegfried, Breitling, Krishnan, Ravindran, Neil M, Goldenberg, Wolfgang M, Kuebler   +3 more
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Omics and Extreme Phenotyping Reveal Longitudinal Association Between Left Atrial Size and Pulmonary Vascular Resistance in Group 2 Pulmonary Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Left heart disease is the most common cause of pulmonary hypertension (PH) and is frequently accompanied by increases in pulmonary vascular resistance.
Neil J. Kelly, David Newhouse, Himal Chapagain, Ashish Patel, Yicheng Tang, Ato Howard, Anna Kirillova, Hee‐Jung J. Kim, Haris Rahman, Wadih El Khoury, Seyed Mehdi Nouraie, Gavin Hickey, Leyla Elif Sade, Sandeep Jain, Stephen Y. Chan   +14 more
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Pulmonary Arterial Hypertension in the Elderly: Peculiar Features and Challenges for a Proper Phenotyping Approach

Journal of Cardiovascular Development and Disease, 2023
(1) Introduction. Although pulmonary arterial hypertension (PAH) usually affects young people with a low cardiovascular risk profile, progressive epidemiologic changes have been providing a codified phenotype of elderly subjects with PAH and increased ...
Riccardo Scagliola, Claudio Brunelli, Manrico Balbi   +2 more
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Left Ventricular Dysfunction in Ischemic Heart Disease

Cardiovascular Innovations and Applications, 2019
Ischemic heart disease is a growing cause of heart failure owing to the increasing prevalence of diabetes, hypertension, and obesity. It is important to understand the concepts of myocardial stunning and hibernation so we as physicians can order ...
Robert F. Hamburger
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Pulmonary Hypertension Due to Left Heart Diseases

Journal of the American College of Cardiology, 2013
Pulmonary hypertension (PH), a common complication of left heart diseases (LHD), negatively impacts symptoms, exercise capacity, and outcome. Although the true prevalence of PH-LHD is unknown, a subset of patients might present significant PH that cannot be explained by a passive increase in left-sided filling pressures. The term "out-of-proportion" PH
Vachiéry, Jean Luc, Adir, Yochai, Barberà, Joan Albert, Champion, Hunter, Coghlan, John Gerard, Cottin, Vincent, De Marco, Teresa, GALIE', NAZZARENO, Ghio, Stefano, Gibbs, J. Simon R, Martinez, Fernando, Semigran, Marc, Simonneau, Gerald, Wells, Athol, Seeger, Werner   +14 more
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Medical Therapies for Heart Failure in Hypoplastic Left Heart Syndrome

Journal of Cardiovascular Development and Disease, 2022
Significant surgical and medical advances over the past several decades have resulted in a growing number of infants and children surviving with hypoplastic left heart syndrome (HLHS) and other congenital heart defects associated with a single systemic ...
Angela N. Baybayon-Grandgeorge, Ashley E. Pietra, Shelley D. Miyamoto, Anastacia M. Garcia   +3 more
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2015 ESC/ERS GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION

Российский кардиологический журнал, 2016
The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS)Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC ...
Nazzareno Galiè, Marc Humbert, Jean-Luc Vachiery, Simon Gibbs, Irene Lang, Adam Torbicki, Gérald Simonneau, Andrew Peacock, Anton Vonk Noordegraaf, Maurice Beghetti, Ardeschir Ghofrani, Miguel Angel Gomez Sanchez, Georg Hansmann, Walter Klepetko, Patrizio Lancellotti, Marco Matucci, Theresa McDonagh, Luc A. Pierard, Pedro T. Trindade, Maurizio Zompatori, Marius Hoeper   +20 more
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