Results 71 to 80 of about 12,985,405 (284)

Survey of Human Mitochondrial Diseases Using New Genomic/Proteomic Tools [PDF]

, 2001
BACKGROUND. We have constructed Bayesian prior-based, amino-acid sequence profiles for the complete yeast mitochondrial proteome and used them to develop methods for identifying and characterizing the context of protein mutations that give rise to human ...
Mohr, Scott C., Plasterer, Thomas N., Smith, Temple F.   +2 more
core   +2 more sources

Powerful yet challenging: mechanistic niche models for predicting invasive species potential distribution under climate change

Ecography, EarlyView.
Risk assessments of invasive species present one of the most challenging applications of species distribution models (SDMs) due to the fundamental issues of distributional disequilibrium, niche changes, and truncation. Invasive species often occupy only a fraction of their potential environmental and geographic ranges, as their spatiotemporal dynamics ...
Erola Fenollosa, Sean E. H. Pang, Natalie J. Briscoe, Antoine Guisan, Roberto Salguero-Gómez   +4 more
wiley   +1 more source

Framework for better living with HIV in England [PDF]

, 2009
Duration: April 2007 - May 2009 Sigma Research was funded by Terrence Higgins Trust to co-ordinate the development of a framework to address the health, social care, support and information needs of people with diagnosed HIV in England.
Azad, Y, Carter, M, Crafer, E, Cregan, S, Keogh, P, Morley, C, Nkwenti, P, Nutland, W, Pebody, R, Reynolds, R, Summerside, J, Weatherburn, P   +11 more
core   +1 more source

Distinct thalamic functional connectivity and volume patterns across focal epilepsies in children: A multimodal neuroimaging study

Epilepsia, EarlyView.
Abstract Objective The thalamus is a key hub in seizure propagation, and its nuclei are emerging targets for neuromodulation. However, the contributions of individual nuclei to epileptic networks remain unclear, particularly in children, who are less studied than adults.
Xiyu Feng, Aswin Chari, Maria H. Eriksson, Freya Prentice, Xiaosong He, Hua Xie, Leigh Sepeta, M. Zubair Tahir, Jonathan D. Clayden, Martin M. Tisdall, Torsten Baldeweg, Rory J. Piper   +11 more
wiley   +1 more source

Stochastic models of population extinction

, 2010
Theoretical ecologists have long sought to understand how the persistence of populations depends on biotic and abiotic factors. Classical work showed that demographic stochasticity causes the mean time to extinction to increase exponentially with ...
Meerson, Baruch, Ovaskainen, Otso
core   +1 more source

IFNγ modestly contributes to disease progression in the Ndufs4 (-/-) model of Leigh syndrome while IP10 is dispensable [PDF]

, 2023
Allison R. Hanaford, Asheema Khanna, Katerina James, Vivian Truong, Ryan Liao, Yihan Chen, Michael Mulholland, Bernhard Kayser, Erin Shien Hsieh, Margaret M. Sedensky, Philip G. Morgan, Vandana Kalia, Surojit Sarkar, Simon C. Johnson   +13 more
openalex   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Leukocyte proliferation mediates disease pathogenesis in the Ndufs4 (KO) mouse model of Leigh syndrome [PDF]

, 2021
Julia Stokes, Rebecca Bornstein, Katerina James, Kyung Yeon Park, Kira A. Spencer, Katie Vo, John Snell, Brittany M. Johnson, Philip G. Morgan, Margaret M. Sedensky, Nathan A. Baertsch, Simon C. Johnson   +11 more
openalex   +1 more source

Minimum Wages, the Earned Income Tax Credit, and Mental Health Around Pregnancy

Health Economics, EarlyView.
ABSTRACT This study estimates the effects on perinatal mental health of the state's minimum wage and earned income tax credit (EITC), controlling for other policies and state‐level factors. Using data from the Pregnancy Risk Assessment Monitoring System for 2012–2018 births we find robust evidence that minimum wages and EITC levels reduce depression ...
Bryce J. Stanley, Karen Smith Conway
wiley   +1 more source

A rare mitochondrial disorder: Leigh sydrome - a case report

Italian Journal of Pediatrics, 2010
Leigh syndrome is a rare progressive neurodegenerative, mitochondrial disorder of childhood with only a few cases documented from India. The clinical presentation of Leigh syndrome is highly variable.
Shrikhande Dhananjay Y, Kalakoti Piyush, Syed MM Aarif, Ahya Kunal, Singh Gurmeet   +4 more
doaj   +1 more source