Results 11 to 20 of about 212,497 (330)
Gene Expression in Leishmania Is Regulated Predominantly by Gene Dosage [PDF]
mBio, 2017 Leishmania tropica, a unicellular eukaryotic parasite present in North and East Africa, the Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous leishmaniasis in displaced populations in Iraq, Jordan, and Syria. Here,
Stefano A Iantorno +9 more
semanticscholar +5 more sources
Cell death in Leishmania [PDF]
Parasite, 2019 Leishmaniases still represent a global scourge and new therapeutic tools are necessary to replace the current expensive, difficult to administer treatments that induce numerous adverse effects and for which resistance is increasingly worrying.
L. Basmaciyan, M. Casanova
semanticscholar +5 more sources
Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background [PDF]
, 2012 The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is ...
A Debrabant +85 more
core +28 more sources
Pathogens, 2020 Leishmania are obligate intracellular parasites known to have developed successful ways of efficient immunity evasion. Because of this, leishmaniasis, a disease caused by these flagellated protists, is ranked as one of the most serious tropical infections worldwide.
Lucie Podešvová +5 more
openaire +3 more sources
Experimental treatment with sodium stibogluconate of hamsters infected with Leishmania (Leishmania) chagasi and Leishmania (Leishmania) amazonensis [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 1999 The present paper reports the experimental treatment of hamsters infected with Leishmania chagasi and Leishmania amazonensis with sodium stibogluconate (20mg/kg/day x 20 days). Only with L. chagasi did the treatment result in the complete elimination of parasites from the spleen. However, no parasitological cure was achieved in hamsters infected with L.
Figueiredo, Elizabeth M. de +2 more
openaire +5 more sources
The first detection of Leishmania major in naturally infected Sergentomyia minuta in Portugal [PDF]
, 2013 Phlebotomine sandflies of the genus Sergentomyia are widely distributed throughout the Old World. It has been suggested that Sergentomyia spp are involved in the transmission of Leishmania in India and Africa, whereas Phlebotomus spp are thought to be ...
Afonso, Maria Odete +5 more
core +3 more sources
Frontiers in Cellular and Infection Microbiology, 2022 Leishmania (L.) species are protozoan parasites with a complex life cycle consisting of a number of developmental forms that alternate between the sand fly vector and their host. The non-pathogenic species L.
Mehrdad Shokouhy +10 more
doaj +1 more source
Complex ecological interactions across a focus of cutaneous leishmaniasis in Eastern Colombia: novel description of Leishmania species, hosts and phlebotomine fauna [PDF]
Royal Society Open Science, 2020 This study aimed to analyse the patterns of diversity, blood sources and Leishmania species of phlebotomines in a focus of cutaneous leishmaniasis in Arboledas, Eastern Colombia.
Claudia M. Sandoval-Ramírez +8 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2016 Background The aim of this study is to describe the major evolutionary historical events among Leishmania, sandflies, and the associated animal reservoirs in detail, in accordance with the geographical evolution of the Earth, which has not been ...
M. Akhoundi +6 more
semanticscholar +1 more source