Results 11 to 20 of about 72,530 (191)

UVA1 radiation attenuates pro‐inflammatory functions in human monocytes

open access: yesThe Journal of Dermatology, Volume 50, Issue 1, Page 46-56, January 2023., 2023
Abstract UVA1 therapy is effective in the treatment of inflammatory and autoimmune skin diseases. The mode of action of UVA1 therapy is not completely understood and especially data on cells of the innate immune system like monocytes, which are critically involved in many inflammatory processes, are sparse. We wanted to answer the question whether UVA1
Anna Franziska Peters   +10 more
wiley   +1 more source

Autochthonous Babesia canis infections in 49 dogs in Germany

open access: yesJournal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 140-149, January/February 2023., 2023
Abstract Background Vector‐borne diseases are of increasing importance in Germany. Since 2015, autochthonous cases have been increasingly documented in Berlin/Brandenburg. Objectives Describe autochthonous Babesia canis infection in the Berlin/Brandenburg region. Animals Forty‐nine dogs with autochthonous B. canis infection.
Christiane Weingart   +7 more
wiley   +1 more source

In vitro screening and in vivo evaluation of antiparasitic phytochemicals against Cryptocaryon irritans in pompano, Trachinotus ovatus

open access: yesJournal of the World Aquaculture Society, Volume 53, Issue 6, Page 1084-1100, December 2022., 2022
Abstract Cryptocaryon irritans, one of the most devastating holotrichous ciliated protozoans, causes massive economic losses in the pompano, Trachinotus ovatus, mariculture industries. Considering the many advantages of phytochemicals, such as low cost, low residuals, and low pollution, they can be a good alternative for the prevention and control of C.
Wei‐Wei Mao   +9 more
wiley   +1 more source

Leishmania kinetoplast DNA contributes to parasite burden in infected macrophages: Critical role of the cGAS-STING-TBK1 signaling pathway in macrophage parasitemia

open access: yesFrontiers in Immunology, 2022
Leishmania parasites harbor a unique network of circular DNA known as kinetoplast DNA (kDNA). The role of kDNA in leishmania infections is poorly understood. Herein, we show that kDNA delivery to the cytosol of Leishmania major infected THP-1 macrophages
Ismail Cem Yilmaz   +14 more
doaj   +1 more source

Trends in malaria indicators after scale-up of community-based malaria management in Afghanistan

open access: yesMalaria Journal, 2022
Background The Community-Based Malaria Management (CBMM) strategy, introduced in 2013 and expanded to all health facilities and health posts in Afghanistan by 2016, aimed to deliver rapid diagnostic testing and more timely treatment to all communities ...
Sayed Daoud Mahmoodi   +10 more
doaj   +1 more source

Vaccination with Leishmania mexicana LPG induces PD-1 in CD8+ and PD-L2 in macrophages thereby suppressing the immune response: A model to assess vaccine efficacy [PDF]

open access: yesVaccine Volume 32, Issue 11, 5 March 2014, Pages 1259-1265, 2019
Leishmania lipophosphoglycan is a molecule that has been used as a vaccine candidate, with contradictory results. Since unsuccessful protection could be related to suppressed T cell responses, we analyzed the expression of inhibitory receptor PD-1 in CD8+ and CD4+ lymphocytes and it is ligand PD-L2 in macrophages of BALB/c mice immunized with various ...
arxiv   +1 more source

In vitro and in vivo antileishmanial efficacy of a combination therapy of diminazene and artesunate against Leishmania donovani in BALB /c mice [PDF]

open access: yesRev. Inst. Med. Trop. Sao Paulo. 2011, 53 (3): 129 - 132, 2011
The in vitro and in vivo activity of diminazene (Dim), artesunate (Art) and combination of Dim and Art (Dim-Art) against Leishmania donovani was compared to reference drug; amphotericin B. IC50 of Dim-Art was found to be $2.28 \pm 0.24 \mu$ g/mL while those of Dim and Art were $9.16 \pm 0.3 \mu$ g/mL and $4.64 \pm 0.48 \mu$ g/mL respectively.
arxiv   +1 more source

Phlebotomine sand flies (Diptera: Psychodidae) associated with changing patterns in the transmission of the human cutaneous leishmaniasis in French Guiana

open access: yesMemorias do Instituto Oswaldo Cruz, 2007
Between March 2000 and December 2001 a survey of the sand flies (Diptera: Phlebotominae) of French Guiana was carried out during 14 nights of captures with CDC light-traps and Malaise traps, and resulted in the collection of 2245 individuals of 38 ...
Florence Fouque   +6 more
doaj   +1 more source

Transient superdiffusion and long-range correlations in the motility patterns of trypanosomatid flagellate protozoa [PDF]

open access: yesPLoS ONE 11(3): e0152092 (2016), 2016
We report on a diffusive analysis of the motion of flagellate protozoa species. These parasites are the etiological agents of neglected tropical diseases: leishmaniasis caused by Leishmania amazonensis and Leishmania braziliensis, African sleeping sickness caused by Trypanosoma brucei, and Chagas disease caused by Trypanosoma cruzi.
arxiv   +1 more source

Enhanced Glycolysis Is Required for Antileishmanial Functions of Neutrophils Upon Infection With Leishmania donovani

open access: yesFrontiers in Immunology, 2021
Visceral leishmaniasis (VL) is a fatal parasitic disease if untreated. Treatment options of VL diminish due to emerging drug resistance. Although the principal host cells for the multiplication of Leishmania are macrophages, neutrophils are the first ...
Mareike Ohms   +8 more
doaj   +1 more source

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