Results 11 to 20 of about 158,924 (268)
Leishmania are obligate intracellular parasites known to have developed successful ways of efficient immunity evasion. Because of this, leishmaniasis, a disease caused by these flagellated protists, is ranked as one of the most serious tropical infections worldwide.
Lucie Podešvová+5 more
openaire +3 more sources
Genome-wide mapping reveals single-origin chromosome replication in Leishmania, a eukaryotic microbe [PDF]
Background DNA replication initiates on defined genome sites, termed origins. Origin usage appears to follow common rules in the eukaryotic organisms examined to date: all chromosomes are replicated from multiple origins, which display variations in ...
Campbell, Samantha J.+4 more
core +2 more sources
Inhibitory effect of O-propargyllawsone in A549 lung adenocarcinoma cells
Background Lung cancer is the deadliest type of cancer in the world and the search for compounds that can treat this disease is highly important. Lawsone (2-hydroxy-1,4-naphtoquinone) is a naphthoquinone found in plants from the Lawsone genus that show a
Edmilson Willian Propheta dos Santos+9 more
doaj +1 more source
Detection of Leishmania DNA in wild foxes and associated ticks in Patagonia, Argentina, 2000 km south of its known distribution area [PDF]
Indexación: Web of Science; PubMedBackground: Zoonotic Visceral Leishmaniasis (ZVL) is a vector-borne disease affecting humans and other mammals and caused by the protozoan parasite Leishmania (Leishmania) infantum (syn. L.
Ferroglio, Ezio+6 more
core +4 more sources
Leishmania (Leishmania) tropica
Published as part of Rioux, Jean-Antoine, Gramiccia, Marina, Léger, Nicole, Desjeux, Philippe & Depaquit, Jérôme, 2020, Leishmaniasis and phlebotomine sand flies in Oman Sultanate, pp. 1-13 in Parasite (Paris, France) (Paris, France) 27 (68) on page 10, DOI: 10.1051/parasite/2020064, http://zenodo.org/record ...
Rioux, Jean-Antoine+4 more
openaire +1 more source
Experimental treatment with sodium stibogluconate of hamsters infected with Leishmania (Leishmania) chagasi and Leishmania (Leishmania) amazonensis [PDF]
The present paper reports the experimental treatment of hamsters infected with Leishmania chagasi and Leishmania amazonensis with sodium stibogluconate (20mg/kg/day x 20 days). Only with L. chagasi did the treatment result in the complete elimination of parasites from the spleen. However, no parasitological cure was achieved in hamsters infected with L.
Figueiredo, Elizabeth M. de+2 more
openaire +5 more sources
Background Melanoma is a malignant cancer that affects melanocytes and is considered the most aggressive skin-type cancer. The prevalence for melanoma cancer for the last five year is about one million cases.
Mariana Nobre Farias de Franca+9 more
doaj +1 more source
Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum. [PDF]
In most organisms, the primary function of homologous recombination (HR) is to allow genome protection by the faithful repair of DNA double-strand breaks.
Buisson, Rémi+9 more
core +2 more sources
Kinetoplastids:related protozoan pathogens, different diseases [PDF]
Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma and Leishmania, which are human pathogens with devastating health and economic effects. The sequencing of the genomes of some of these species has highlighted their
Agranoff+127 more
core +3 more sources