Results 21 to 30 of about 169,942 (293)

In Vitro Screening Test Using Leishmania Promastigotes Stably Expressing mCherry Protein [PDF]

, 2014
Transgenic Leishmania major and Leishmania donovani axenic promastigotes constitutively expressing mCherry were used for in vitro antileishmanial drug screening. This method requires minimal sample manipulation and can be easily adapted to automatic drug
Miguel A. Morales, Vacchina, Paola
core   +2 more sources

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]

, 2016
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E, Cruz Cervera, E, Diro, E, Getahun, M, Hailu, A, Kropf, P, Lemma, M, Melkamu, R, Mengesha, B, Mesfin, G, Modolell, M, Muller, I, Munder, M, Skhedy, Z, Tajebe, F, Takele, Y, Van der Auwera, G, Yardley, V, Yeshanew, A, Yizengaw, E   +19 more
core   +3 more sources

Trends in malaria indicators after scale-up of community-based malaria management in Afghanistan

Malaria Journal, 2022
Background The Community-Based Malaria Management (CBMM) strategy, introduced in 2013 and expanded to all health facilities and health posts in Afghanistan by 2016, aimed to deliver rapid diagnostic testing and more timely treatment to all communities ...
Sayed Daoud Mahmoodi, Abdul Alim Atarud, Ahmad Walid Sediqi, Sarah Gallalee, Willi McFarland, Temesgen Birara Aynie, Mohmmad Sami Nahzat, Hamida Hamid, Ghulam Qader Qader, Mohammad Shoaib Tamim, Ali Mirzazadeh   +10 more
doaj   +1 more source

Sphingolipid Degradation in Leishmania (Leishmania) amazonensis

PLoS Neglected Tropical Diseases, 2012
Human leishmaniasis is caused by more than 20 Leishmania species and has a wide range of symptoms. Our recent studies have demonstrated the essential role of sphingolipid degradation in the virulence of Leishmania (Leishmania) major, a species responsible for localized cutaneous leishmaniasis in the Old World.
Agiesh Balakrishna Pillai, Wei Xu, Ou Zhang, Kai Zhang   +3 more
openaire   +4 more sources

Phlebotomine sand flies (Diptera: Psychodidae) associated with changing patterns in the transmission of the human cutaneous leishmaniasis in French Guiana

Memorias do Instituto Oswaldo Cruz, 2007
Between March 2000 and December 2001 a survey of the sand flies (Diptera: Phlebotominae) of French Guiana was carried out during 14 nights of captures with CDC light-traps and Malaise traps, and resulted in the collection of 2245 individuals of 38 ...
Florence Fouque, Pascal Gaborit, Jean Issaly, Romuald Carinci, Jean-Charles Gantier, Christophe Ravel, Jean-Pierre Dedet   +6 more
doaj   +1 more source

The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models. [PDF]

, 2016
Toll-like receptors (TLRs) play an important role in the innate and adaptive immune responses to pathogens, and are the target of new vaccine adjuvants.
Bates, PA, Guimarães, A, Halliday, A, Taylor, MJ, Turner, JD   +4 more
core   +7 more sources

Leishmania (Leishmania) amazonenisInfection, Suriname

Emerging Infectious Diseases, 2008
To the Editor: A 17-year-old man was seen at the Dermatology Service in Paramaribo (Suriname) with a skin condition that he had had since he was 5 years of age. The condition consisted of multiple cutaneous ulcerations, nodules, and fibrotic plaques disseminated on his face, limbs, and trunk, and subcutaneous nodules on lymph-draining tracts on his ...
van der Meide, W., de Vries, H.J.C., Pratlong, F., van der Wal, A.C., Sabajo, L.   +4 more
openaire   +4 more sources

Native rodent species are unlikely sources of infection for Leishmania (Viannia) braziliensis along the Transoceanic Highway in Madre de Dios, Peru. [PDF]

, 2014
An estimated 2.3 million disability-adjusted life years are lost globally from leishmaniasis. In Peru's Amazon region, the department of Madre de Dios (MDD) rises above the rest of the country in terms of the annual incidence rates of human leishmaniasis.
Conrad, Patricia A, De Los Santos, Maxy, Ghersi, Bruno M, Lescano, Andres G, Mazet, Jonna AK, Montgomery, Joel M, Razuri, Hugo, Shender, Lisa A   +7 more
core   +4 more sources

Rapid Detection of Leishmania infantum Infection in Dogs: Comparative Study Using an Immunochromatographic Dipstick Test, Enzyme-Linked Immunosorbent Assay, and PCR [PDF]

, 2002
Current zoonotic visceral leishmaniasis (ZVL) control programs in Brazil include the culling of Leishmania infantum-infected reservoir dogs, a strategy that has failed to prevent a rise of canine and human ZVL cases over the past decade.
Bruce Alex, Bruce Alex, Clive R. Davies, Clive R. Davies, J. Clin Microbiol, Richard Reithinger, Richard Reithinger, Rupert J. Quinnell, Rupert J. Quinnell   +8 more
core   +3 more sources

Visualization of Leishmania tropica Infection in BALB/c Mice by Bioluminescence Imaging

Iranian Biomedical Journal, 2020
Background: Leishmania tropica is the cause of more than one form of leishmaniasis and lacks a known reservoir animal. This study compares the potential infectivity of recombinant and wild-type L. tropica in BALB/c mice.
Mahdieh Eskandar, Elham Gholami, Negar Seyed, Yasaman Taslimi, Sima Habibzadeh, Sima Rafati, Tahereh Taheri   +6 more
doaj