Results 41 to 50 of about 56,189 (179)

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Production of Recombinant Leishmania Tropica Parasites Expressing Two Proteins of Egfp and Luciferase Reporter

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017
BACKGROUND AND OBJECTIVE: L. tropica is the major cause of cutaneous and visceral leishmaniasis in Iran. Due to lack of an accurate, sensitive and noninvasive detection test in animal model is a major problem. Here, we designed L.
T Taheri, M Eskandar, S Rafati
doaj  

Genome-wide quantification of polycistronic transcription in Leishmania major

mBio
Leishmania major is a human-pathogenic, obligate parasite and the etiological agent of the most prevalent, cutaneous form of leishmaniasis, which is an important neglected, tropical disease with ~1.2 million new infections per year.
Janne Grünebast, Stephan Lorenzen, Joachim Clos   +2 more
doaj   +1 more source

Coinfección VIH leishmania

Iatreia, 1992
La disminución de las defensas del huésped consecutiva a la Infección por el VIH es la base de las complicaciones oportunistas del paciente con SIDA; una de éstas puede ser la leishmaniosis visceral, reportada recientemente en Brazil, España e Italia. La infección por Leishmania puede tener lugar antes o después de la infección viral.
openaire   +3 more sources

Late Onset Telomere Biology Disorder Presenting With Pancytopenia, Immune Dysregulation, Interstitial Lung Disease and Alopecia

American Journal of Hematology, EarlyView.
Bo A. Wan, Hamish Nicolson, Heather A. Leitch, Ryan J. Stubbins, Luke Y. C. Chen, Timothy Murray, Amy Trottier, Anthony Gador   +7 more
wiley   +1 more source

Potential vectors of Leishmaniases in the Environmental Protection Area and Tinguá Federal Biological Reserve, Municipality of Nova Iguaçu, Rio de Janeiro, Brazil

Medical and Veterinary Entomology, EarlyView.
This study was to describe the composition of sand fly fauna, detect potential vectors of Leishmania spp. in the Tinguá district, an ATL endemic, Rio de Janeiro, Brazil. Seven species of vectorial importance in the epidemiological cycle of leishmaniasis was observed: Nyssomyia intermedia, Migonemyia migonei, Pintomyia fischeri, Psychodopygus hirsutus ...
Antônio L. F. Santana, Alfredo C. R. Azevedo, Margarete M. S. Afonso, Bruno M. Carvalho, Vanessa R. Vieira, Simone M. Costa, Júlia S. Silva, Thais A. Pereira, Daniela P. Pereira, Maurício L. Vilela   +9 more
wiley   +1 more source

Knowledge, attitudes and practices about Visceral leishmaniasis in three communes of Neiva, Huila

Revista Habanera de Ciencias Médicas, 2023
Introduction: Visceral leishmaniasis is a zoonotic disease transmitted by vectors of the Lutzomyia genus, distributed in 98 countries, including Colombia, which can cause a serious clinical picture that, in the absence of treatment, can be fatal ...
Paola Aranzazu Garzon Polania, Maria Camila Charry Camacho, Angel David Salas Medina, Maria Eugenia Hernández Valenzuela, Juan Carlos Zambrano Arteaga   +4 more
doaj  

Flavopereirine—An Alkaloid Derived from Geissospermum vellosii—Presents Leishmanicidal Activity In Vitro

Molecules, 2019
Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs, low efficacy of alternative treatments, and resistance of the parasite.
João Victor da Silva e Silva, Helliton Patrick Cordovil Brigido, Kelly Cristina Oliveira de Albuquerque, Josiwander Miranda Carvalho, Jordano Ferreira Reis, Lara Vinhal Faria, Márlia Regina Coelho-Ferreira, Fernando Tobias Silveira, Agnaldo da Silva Carneiro, Sandro Percário, Andrey Moacir do Rosário Marinho, Maria Fâni Dolabela   +11 more
doaj   +1 more source

Unravelling the biochemical aspects of the interaction between ticks and Leishmania using a tick cell line

Medical and Veterinary Entomology, EarlyView.
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre, Karoline dos Anjos Lima, Fernanda de Paula Pepino, Daniela Cosentino‐Gomes, Adivaldo Fonseca, Lesley Bell‐Sakyi, Georgia Correa Atella, Lucia H. Pinto‐da‐Silva   +7 more
wiley   +1 more source

Optimization of the Timing of Induction for the Assessment of Nitric Oxide Production in Leishmania major Infected Macrophage Cells

Iranian Journal of Parasitology, 2016
Background: The present study was conducted to investigate the optimized timing for macrophages induction and nitric oxide (NO) production against invading Leishmania parasite. Methods: The present study examined the murine macrophage cell line, B10R,
Somaye SADEGHI, Negar SEYED, Sima RAFATI, Tahereh TAHERI   +3 more
doaj