Results 61 to 70 of about 72,530 (191)

Intralesional gene expression profile of JAK-STAT signaling pathway and associated cytokines in Leishmania tropica-infected patients

Frontiers in Immunology
BackgroundThe JAK-STAT signaling pathway is a central cascade of signal transduction for the myriad of cytokines in which dysregulation has been implicated in progression of inflammatory and infectious diseases.
Shima Hadifar, Nasrin Masoudzadeh, Hossein Heydari, Vahid Mashayekhi Goyonlo, Mohammadali Kerachian, Maryam Daneshpazhooh, Ali Sadeghnia, Nasim Tootoonchi, Reza Erfanian Salim, Sima Rafati, Ali M. Harandi   +10 more
doaj   +1 more source

Leukocyte Behavior in Mesenteric Microcirculation upon Experimental By Leishmania Spp. in BALB/c Mice

Iranian Journal of Parasitology, 2021
Background: We aimed to determine the cellular recruitment (leukocyte rolling and adhesion) by which the Leishmania (Viannia) braziliensis, L. (Leishmania) amazonensis, and L. (Leishmania) major species in the mesenteric microcirculation of BALB/c mice.
Herintha Coeto Neitzke-Abreu, Rhuan Carlos Souza Caetano, Kárin Rosi Reinhold-Castro, Manoel Sebastião da Costa Lima-Junior, Wagner José Tenório dos Santos, Gessilda de Alcantara Nogueira de Melo, Roberto Kenji Nakamura Cuman, Sandra Mara Alessi Aristides, Thais Gomes Verzignassi Silveira, Maria Valdrinez Campana Lonardoni   +9 more
doaj  

Flavopereirine—An Alkaloid Derived from Geissospermum vellosii—Presents Leishmanicidal Activity In Vitro

Molecules, 2019
Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs, low efficacy of alternative treatments, and resistance of the parasite.
João Victor da Silva e Silva, Helliton Patrick Cordovil Brigido, Kelly Cristina Oliveira de Albuquerque, Josiwander Miranda Carvalho, Jordano Ferreira Reis, Lara Vinhal Faria, Márlia Regina Coelho-Ferreira, Fernando Tobias Silveira, Agnaldo da Silva Carneiro, Sandro Percário, Andrey Moacir do Rosário Marinho, Maria Fâni Dolabela   +11 more
doaj   +1 more source

Coagulation status of immune‐mediated polyarthritis in dogs

Journal of Small Animal Practice, EarlyView.
Objective To describe the coagulation status of dogs with immune‐mediated polyarthritis. Materials and Methods Hospital records at a single referral centre were retrospectively reviewed for dogs diagnosed with immune‐mediated polyarthritis. Cases were classified as hypercoagulable, normocoagulable, hypocoagulable, or hypercoagulable and hypocoagulable ...
L. A. F. Packham, V. Black
wiley   +1 more source

Innate Immunity Plays a Key Role in Leishmania Infection: Implications for Vaccine Design

Journal of Medical Microbiology and Infectious Diseases, 2016
Neutrophils are part of the first line of immune response and are essential for resistance against a variety of pathogens. They professionally mediate direct killing of pathogens, recruit other phagocytes by specific chemokines, produce cytokines and ...
Negar Seyed, Sima Rafati
doaj  

Steroid‐responsive generalised sterile necrotising pyogranulomatous lymphadenitis in a cat

Journal of Small Animal Practice, EarlyView.
A 1.5‐year‐old neutered male cat was presented with fever, inappetence, lethargy and marked generalised lymphadenopathy of 4 days duration. Excisional biopsy of peripheral lymph nodes revealed necrotising pyogranulomatous lymphadenitis. Extensive investigation failed to identify an underlying infectious [bacterial (Bartonella, Mycobacteria, Mycoplasma,
L. Lecot, E. Ramery, M. Hugonnard, A. Tortereau, É. Krafft   +4 more
wiley   +1 more source

Integrated analysis of lncRNA and mRNA expression profiles in cutaneous leishmaniasis lesions caused by Leishmania tropica

Frontiers in Cellular and Infection Microbiology
BackgroundCutaneous leishmaniasis (CL), caused by Leishmania (L.) species, remains a neglected tropical disease in many developing countries. We and others have shown that different Leishmania species can alter the gene expression profile of human host ...
Shima Hadifar, Nasrin Masoudzadeh, Björn Andersson, Hossein Heydari, Vahid Mashayekhi Goyonlo, Mohammadali Kerachian, Josefine Persson, Hasan Rahimi-Tamandegani, Reza Erfanian Salim, Sima Rafati, Ali M. Harandi   +10 more
doaj   +1 more source

A case of visceral leishmaniasis mimicking connective tissue disease

Rheumatology &Autoimmunity, EarlyView.
Yucui Li, Hongxia Yang, Tingzi Zhao, Ke Xu, Liyun Zhang   +4 more
wiley   +1 more source

NÍVEL DE CONHECIMENTOS SOBRE LEISHMANIOSE TEGUMENTAR AMERICANA ENTRE MORADORES DA VILA DO APIAÚ, MUNICÍPIO DE MUCAJAÍ, RORAIMA, BRASIL

Ambiente, 2012
Realizou­se estudo visando identificar os conhecimentos que os moradores da vila do Apiaú, (município de Mucajaí, Estado de Roraima) têm sobre a LTA (Leishmaniose Tegumentar Americana), visando à indicação de medidas de controle da transmissão da doença ...
Jaime de Liege Gama Neto, Clésia de Souza Paulo, Mahedy Araujo Bastos Passos   +2 more
doaj   +1 more source

Synthesis and biological evaluation of thiazole derivatives as LbSOD inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Leishmaniasis is considered as one of the major neglected tropical diseases due to its magnitude and wide geographic distribution. Leishmania braziliensis, responsible for cutaneous leishmaniasis, is the most prevalent species in Brazil.
Camila C. Bitencourt Brito, Hélder Vinicius Carneiro da Silva, Daci José Brondani, Antonio Rodolfo de Faria, Rafael Matos Ximenes, Ivanildo Mangueira da Silva, Julianna F. C. de Albuquerque, Marcelo Santos Castilho   +7 more
doaj   +1 more source