Results 71 to 80 of about 129,759 (292)
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017 BACKGROUND AND OBJECTIVE: L. tropica is the major cause of cutaneous and visceral leishmaniasis in Iran. Due to lack of an accurate, sensitive and noninvasive detection test in animal model is a major problem. Here, we designed L.
T Taheri, M Eskandar, S Rafati
doaj
Genome-wide quantification of polycistronic transcription in Leishmania major
mBioLeishmania major is a human-pathogenic, obligate parasite and the etiological agent of the most prevalent, cutaneous form of leishmaniasis, which is an important neglected, tropical disease with ~1.2 million new infections per year.
Janne Grünebast +2 more
doaj +1 more source
Parasites & Vectors, 2018 Leishmaniasis is an emerging disease in Thailand with an unknown incidence or prevalence. Although the number of properly characterized and clinically confirmed cases is about 20, it is suspected that this low number masks a potentially high prevalence ...
N. Jariyapan +9 more
semanticscholar +1 more source
Iatreia, 1992 La disminución de las defensas del huésped consecutiva a la Infección por el VIH es la base de las complicaciones oportunistas del paciente con SIDA; una de éstas puede ser la leishmaniosis visceral, reportada recientemente en Brazil, España e Italia. La infección por Leishmania puede tener lugar antes o después de la infección viral.
openaire +3 more sources
The FEBS Journal, EarlyView.Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk +8 more
wiley +1 more source
Knowledge, attitudes and practices about Visceral leishmaniasis in three communes of Neiva, Huila
Revista Habanera de Ciencias Médicas, 2023 Introduction: Visceral leishmaniasis is a zoonotic disease transmitted by vectors of the Lutzomyia genus, distributed in 98 countries, including Colombia, which can cause a serious clinical picture that, in the absence of treatment, can be fatal ...
Paola Aranzazu Garzon Polania +4 more
doaj
The FEBS Journal, EarlyView.The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini +6 more
wiley +1 more source
Iranian Journal of Parasitology, 2016 Background: The present study was conducted to investigate the optimized timing for macrophages induction and nitric oxide (NO) production against invading Leishmania parasite. Methods: The present study examined the murine macrophage cell line, B10R,
Somaye SADEGHI +3 more
doaj
Molecules, 2019 Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs, low efficacy of alternative treatments, and resistance of the parasite.
João Victor da Silva e Silva +11 more
doaj +1 more source
Gene Expression in Leishmania Is Regulated Predominantly by Gene Dosage
mBio, 2017 Leishmania tropica, a unicellular eukaryotic parasite present in North and East Africa, the Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous leishmaniasis in displaced populations in Iraq, Jordan, and Syria. Here,
Stefano A Iantorno +9 more
semanticscholar +1 more source