Results 81 to 90 of about 158,924 (268)
Particle &Particle Systems Characterization, EarlyView.This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr +5 more
wiley +1 more source
Evidence for regulated expression of Telomeric Repeat-containing RNAs (TERRA) in parasitic trypanosomatids [PDF]
, 2017 The Telomeric Repeat-containing RNAs (TERRA) participate in the homeostasis of telomeres in higher eukaryotes. Here, we investigated the expression of TERRA in Leishmania spp.
Damasceno, Jeziel D. +3 more
core +1 more source
Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy [PDF]
, 2017 Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various ...
Ali, Juma A.M. +7 more
core +2 more sources
Biomedicine & Pharmacotherapy, 2018 Leishmania (Leishmania) amazonensis and Leishmania infantum (=Leishmania chagasi) are protozoa that cause American cutaneous and visceral leishmaniasis, respectively. These diseases show a high incidence in developing countries such as Brazil. The treatments used for leishmaniasis are still limited due to their high cost and toxicity.
Hervé Rogez +8 more
openaire +3 more sources
Long‐term survival in a dog with suspected primary nodal plasmacytoma treated with surgical excision
Veterinary Record Case Reports, EarlyView.Abstract An 8‐year‐old Staffordshire bull terrier presented for left submandibular lymphadenopathy. Cytology showed a monomorphic population of mature plasma cells suggestive of plasma cell neoplasia. On physical examination, no other lymphadenomegaly, cutaneous or oral lesions were found.
Celia Figueroa‐González +4 more
wiley +1 more source
Changing pattern of visceral leishmaniasis, United Kingdom, 1985-2004. [PDF]
, 2006 A 20-year (1985-2004) retrospective review of 39 patients with imported visceral leishmaniasis found that tourism to Mediterranean countries and HIV infection were associated with visceral leishmaniasis. Diagnosis was often delayed.
Bruceson, Anthony DM +3 more
core +3 more sources
Microbiology Resource Announcements, 2019 We present here the draft genome sequences of Leishmania ( Leishmania ) amazonensis , Leishmania ( Leishmania ) mexicana , and Leishmania ( Leishmania
Lori A. Rowe +7 more
openaire +3 more sources
Cell death in Leishmania [PDF]
Parasite, 2019 Leishmaniases still represent a global scourge and new therapeutic tools are necessary to replace the current expensive, difficult to administer treatments that induce numerous adverse effects and for which resistance is increasingly worrying. In this context, the particularly original organization of the Leishmania parasite in comparison to higher ...
Basmaciyan, Louise, Casanova, Magali
openaire +4 more sources
Enrichment of Helminth Mitochondrial Genomes From Faecal Samples Using Hybridisation Capture
Molecular Ecology Resources, EarlyView.ABSTRACT New approaches are urgently needed to enrich rare or low‐abundant DNA in complex samples. Soil‐transmitted helminths (STHs) inhabit heterogeneous environments, including the gastrointestinal tract of their host as adults and are excreted as eggs and larvae in faeces, complicating our understanding of their biology and the use of genetic tools ...
Marina Papaiakovou +7 more
wiley +1 more source
Iranian Journal of Parasitology, 2016 Background: The present study was conducted to investigate the optimized timing for macrophages induction and nitric oxide (NO) production against invading Leishmania parasite. Methods: The present study examined the murine macrophage cell line, B10R,
Somaye SADEGHI +3 more
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