Results 91 to 100 of about 10,019 (223)
, 2017 Objetivo. Determinar la frecuencia de anticuerpos circulantes de Trypanosoma cruzi (T. cruzi), Leishmania mexicana (L. mexicana) y Leishmania braziliensis (L.
Arjona J, Guadalupe +13 more
core +1 more source
Relapsing Nasal Septal Leishmaniasis: Lessons in Long‐Term Multidisciplinary Management Case Report
Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.Introduction Mucosal leishmaniasis (ML) is a rare, destructive, and recurrent protozoal infection caused by Leishmania species, most commonly Leishmania braziliensis. ML can develop months to years after initial cutaneous leishmaniasis (CL) and may lead to severe mucosal destruction if untreated.
Emily Ehsan +4 more
wiley +1 more source
Unveiling the Silent Regulators: Noncoding RNAs in Parasitic Disease Diagnosis and Therapy
Journal of Parasitology Research, Volume 2026, Issue 1, 2026.Parasitic diseases remain a major global health burden, particularly in tropical and low‐resource regions, where limitations in early diagnosis and effective therapeutics contribute to high morbidity and mortality. Emerging evidence highlights noncoding RNAs (ncRNAs) as critical regulators of host–parasite interactions, offering novel opportunities for
Neyon Loku Gamage +2 more
wiley +1 more source
Structural and functional studies of Leishmania braziliensis Hsp90
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013 The ubiquitous Hsp90 is critical for protein homeostasis in the cells, stabilizing "client" proteins in a functional state. Hsp90 activity depends on its ability to bind and hydrolyze ATP, involving various conformational changes that are regulated by co-chaperones, posttranslational modifications and small molecules.
Silva, K.P. +2 more
openaire +2 more sources
Revista do Instituto de Medicina Tropical de São Paulo, 2002 DNA amplification by the polymerase chain reaction (PCR) was applied in the investigation of the presence of Leishmania (Kinetoplastida: Trypanosomatidae) parasites in single phlebotomine sandflies.
MICHALSKY Érika M. +4 more
doaj
PLoS ONE, 2019 Canine cutaneous leishmaniasis (CCL) is a zoonosis of public health interest, and in the Americas, Leishmania (Viannia) braziliensis has been identified as the main etiological agent. The present study sought to investigate Leishmania spp.
Andreia Fernandes Brilhante +11 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2019 Leishmaniasis is a neglected tropical disease caused by parasites of the genus Leishmania (NTD) endemic in 98 countries. Although some drugs are available, current treatments deal with issues such as toxicity, low efficacy, and emergence of resistance ...
Joyce V.B. Borba +7 more
doaj +1 more source
Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa.
, 2005 In this paper we describe the preparation of some biphenylquinuclidine derivatives and their evaluation as inhibitors of squalene synthase in order to explore their potential in the treatment of the parasitic diseases leishmaniasis and Chagas disease ...
Croft, Simon L +15 more
core +1 more source
Frontiers in Microbiology, 2017 Inositol phosphorylceramide (IPC), the major sphingolipid in the genus Leishmania but not found in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis.
Erica V. De Castro Levatti +7 more
doaj +1 more source
Heterogeneity of cysteine proteinases in Leishmania braziliensis and Leishmania major.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 1994 Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) with acrylamide copolymerized with gelatin (substrate-SDS-PAGE) was used to compare promastigote proteinases from two Leishmania species (L. braziliensis and L. major-like). Substrate-SDS-PAGE resolved at least 6 distinct proteinase activities with relative molecular masses between 20
C R, Alves +2 more
openaire +2 more sources