Results 71 to 80 of about 10,019 (223)

Brain Involvement in Leishmaniasis

Cell Biochemistry and Function, Volume 44, Issue 4, April 2026.
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Camila S. Freitas, Eduardo A. F. Coelho, Myron Christodoulides   +2 more
wiley   +1 more source

Comparative microsatellite typing of new world leishmania infantum reveals low heterogeneity among populations and its recent old world origin. [PDF]

, 2011
Leishmania infantum (syn. L. chagasi) is the causative agent of visceral leishmaniasis (VL) in the New World (NW) with endemic regions extending from southern USA to northern Argentina.
Michael A. Miles, Thierry Wirth, Alam, MZ,, Ferreira, Gabriel Eduardo M, Kuhls Katrin, Kuhls, Katrin, Alam Mohammad Zahangir, Mauricio, Isabel L., Oddone Rolando, Gabriel Eduardo M Ferreira, Schönian Gabriele, M. Dora Feliciangeli, Michael A Miles, Feliciangeli, M. Dora, Cupolillo Elisa, Miles Michael A., Miles, Michael A., Alam, Mohammad Zahangir, Isabel L Mauricio, Oddone, Rolando, Isabel L. Mauricio, M Dora Feliciangeli, Mohammad Zahangir Alam, Ferreira Gabriel Eduardo M., Kuhls , K,, Wirth Thierry, Cupolillo, Elisa, Mauricio, Isabel Larguinho, Katrin Kuhls, Mauricio, Isabel L, Wirth, Thierry, Feliciangeli M. Dora, Ferreira, Gabriel Eduardo M., Miles, Michael A, Gabriel Eduardo M. Ferreira, Rolando Oddone, Feliciangeli, M Dora, Mauricio Isabel L., Gabriele Schönian, Elisa Cupolillo, Schönian, Gabriele   +40 more
core   +1 more source

Development of Colombian isolates of Leishmania (Viannia) panamensis, Le. (V.) guyanensis and Le. (V.) braziliensis in the sandfly Lutzomyia intermedia (Lutz & Neiva, 1912) under experimental conditions

Memorias do Instituto Oswaldo Cruz, 1993
The development of Colombian Leishmania species of the subgenus Viannia in Lutzomyia intermedia was similar to that observed with Brazilian Le. (V.) braziliensis: colonization of the pylorus by paramastigotes; promastigotes in the midgut and massive ...
Elizabeth Ferreira Rangel, Bruno L. Travi, André F. Barbosa, James Montoya   +3 more
doaj   +1 more source

The Regulatory Effect of Histone Deacetylase (HDAC) 1 and 2 on iNOS, IL‐6, TNF‐α and IL‐10 Expression in Canine Macrophages Infected With Leishmania infantum

Parasite Immunology, Volume 48, Issue 4, April 2026.
ABSTRACT Zoonotic visceral leishmaniasis is caused by Leishmania (Leishmania) infantum. Dogs are considered the most critical urban reservoirs of L. (L.) infantum due to their high infection rate and direct transmission to humans. The parasite has developed mechanisms to evade the host's defence system by inhibiting macrophage activation, thereby ...
Gabriela Lovizutto Venturin, Lucas Takeshi Siqueira Ito, Gisele Mitsue Umino, Gabriela Torres Rebech, Flávia Lombardi Lopes, Valéria Marçal Felix de Lima   +5 more
wiley   +1 more source

Nota sobre infecção natural de Oryzomys capito laticeps em foco enzoótico de leishmaniose tegumentar no Estado de São Paulo, Brasil Natural infection of Oryzomys capito laticeps in enzootic focus of cutaneous leishmaniasis in S. Paulo State, Brazil

Revista de Saúde Pública, 1973
Assinala-se o isolamento de cepa de Leishmania braziliensis braziliensis em exemplar de Oryzomys capito laticeps capturado em foco enzoótico do Estado de São Paulo, Brasil.
Oswaldo Paulo Forattini, Dino B. G. Pattoli, Ernesto Xavier Rabello, Octávio Alves Ferreira   +3 more
doaj   +1 more source

Stunning Intricacies of RNA Editing Complexes RECC, RESC, and REH2C: Functional Organization, Developmental Regulation, and Evolutionary History in Kinetoplastid Protists

WIREs RNA, Volume 17, Issue 2, March/April 2026.
U‐indel RNA editing targets mRNA:gRNA duplexes through three key complexes that collectively govern assembly, specificity, catalysis, and developmental regulation. Modern tools, including artificial intelligence, analyze the organization, dynamics, and evolution of the remarkable holo‐editosome, opening new avenues in RNA biology and therapy.
Suzanne M. McDermott, Julius Lukeš, Laurie K. Read, Reza Salavati, Achim Schnaufer, Sara L. Zimmer, Jason Carnes, Alasdair Ivens, Naghmeh Poorinmohammad, Nicholas J. Savill, Dave Speijer, Ken Stuart, Kristína Záhonová, Poorya Mirzavand Borujeni, Zihao Chen, Cody Goode, Sunil Kumar Sharma, Lars O’Hara, Jorge Cruz‐Reyes   +18 more
wiley   +1 more source

Investigating the role of the Leishmania (Leishmania) major HASP and SHERP genes during metacyclogenesis in the sand fly vectors, Phlebotomus (Phlebotomus) papatasi and Ph. (Ph.) duboscqi [PDF]

, 2013
Leishmania parasites are the causative agents of a diverse spectrum of infectious diseases termed the leishmaniases. These digenetic parasites exist as intracellular, aflagellate amastigotes in a mammalian host and as extracellular flagellated ...
Doehl, Johannes
core  

Identification of the HSP70-II gene in Leishmania braziliensis HSP70 locus: genomic organization and UTRs characterization

Parasites & Vectors, 2011
Background The heat stress suffered by Leishmania sp during its digenetic life-cycle is a key trigger for its stage differentiation. In Leishmania subgenera two classes of HSP70 genes differing in their 3' UTR were described.
Puerta Concepción J, Requena José M, Ramírez César A   +2 more
doaj   +1 more source

Leishmania species and clinical characteristics of Pacific and Amazon cutaneous leishmaniasis in Ecuador and determinants of health-seeking delay: a cross-sectional study

BMC Infectious Diseases, 2023
Background Cutaneous Leishmaniasis (CL) affects up to 5.000 people in Ecuador each year. L. guyanensis and L. braziliensis are the most common of the eight CL-causing Leishmania species.
Jacob M. Bezemer, Byron P. Freire-Paspuel, Henk D. F. H. Schallig, Henry J.C. de Vries, Manuel Calvopiña   +4 more
doaj   +1 more source

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto, Gustavo Clauss, Jennyfer Castro, Marcus S. A. Garcia, Natasha M. Cassani, Bruna C. Sandim, Ana Laura C. Oliveira, Stephanie P. B. Reyes, Nádija N. P. da Silva, Fillipe V. Rocha, Ana C. G. Jardim, Danilo C. Miguel, Camilla Abbehausen   +12 more
wiley   +1 more source