Resistance of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensisto nitric oxide correlates with disease severity in Tegumentary Leishmaniasis [PDF]
Background Nitric oxide (NO•) plays a pivotal role as a leishmanicidal agent in mouse macrophages. NO• resistant Escherichia coli and Mycobacterium tuberculosis have been associated with a severe outcome of these diseases.
Angela Giudice +63 more
core +1 more source
Leishmania infantum induces high phagocytic capacity and intracellular nitric oxide production by human proinflammatory monocyte [PDF]
BACKGROUND The mechanism of resistance to SbIII in Leishmania is complex, multifactorial and involves not only biochemical mechanisms, but also other elements, such as the immune system of the host.
Christiana Vargas Ribeiro +6 more
doaj +2 more sources
Protection and Pathology in Leishmania braziliensis Infection
Leishmania killing is mediated by IFN-γ-activated macrophages, but IFN-γ production and macrophage activation are insufficient to control L. braziliensis infection. In American tegumentary leishmaniasis (ATL), pathology results from an exaggerated inflammatory response.
Augusto M. Carvalho +2 more
openaire +3 more sources
The spiny rat Proechimys guyannensis (Rodentia: Echimydae) fails to respond to intradermal inoculation with Leishmania (Viannia) braziliensis [PDF]
Leishmaniasis a disease of worldwide occurrence is caused by protozoa of the Leishmania genus. In Brazil, Leishmania (Viannia) braziliensis is the main parasite responsible for the American cutaneous leishmaniasis.
Stela Rechinelli PASSOS +3 more
doaj +2 more sources
Sclerosing Orbital Inflammation Caused by Leishmania braziliensis [PDF]
Orbital biopsy of nonspecific orbital inflammation, commonly referred to as “orbital pseudotumor,” typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital ...
Antonio Augusto V, Cruz +6 more
openaire +2 more sources
Num foco de leishmaniose tegumentar, em Jacarepaguá, Rio de Janeiro, foi encontrado um exemplar de Lutzomyia intermedia naturalmente infectado com Leishmania braziliensis.In a focus of cutaneous leishmaniasis in Jacarepaguá, Rio de janeiro, one specimen ...
Elizabeth Ferreira Rangel +3 more
doaj +1 more source
Parasites belonging to Leishmania braziliensis, Leishmania donovani, Leishmania mexicana complexes and Trypanosoma cruzi (clones 20 and 39) were searched in blood, lesions and strains collected from 28 patients with active cutaneous leishmaniasis and one
B Bastrenta +9 more
doaj +1 more source
Comparative study of parasitological techniques for demonstration of amastigotes and primary isolation of promastigotes in American Cutaneous leishmaniasis [PDF]
FUNDAMENTOS: O PCR tem alta sensibilidade no diagnóstico da LTA, mas é caro e distante da prática. A cultura e o esfregaço são práticos, mas pouco sensíveis.
Andrade, Gilberto Brown de +4 more
core +2 more sources
Assinala-se o isolamento de cepa de Leishmania braziliensis braziliensis em exemplar de Oryzomys capito laticeps capturado em foco enzoótico do Estado de São Paulo, Brasil.
Oswaldo Paulo Forattini +3 more
doaj +1 more source
Expanding the knowledge about Leishmania species in wild mammals and dogs in the Brazilian savannah [PDF]
Background: Wild, synanthropic and domestic mammals act as hosts and/or reservoirs of several Leishmania spp. Studies on possible reservoirs of Leishmania in different areas are fundamental to understand host-parasite interactions and develop strategies ...
AG Schijman +57 more
core +2 more sources

