Results 41 to 50 of about 6,448 (173)
Revista do Instituto de Medicina Tropical de São Paulo, 1991 Three isolates over 5 years from a patient with persistent relapsing mucosal leishmaniasis due to Leishmania (Viannia) braziliensis and 7 clones from one of these isolates were studied by zymodemes and scrodemes analysis.
César Augusto Cuba-Cuba +3 more
doaj +1 more source
Pterocarpanquinone LQB-118 induces apoptosis in Leishmania (Viannia) braziliensis and controls lesions in infected hamsters. [PDF]
PLoS ONE, 2014 Previous results demonstrate that the hybrid synthetic pterocarpanquinone LQB-118 presents antileishmanial activity against Leishmania amazonensis in a mouse model.
Luciana Costa +8 more
doaj +1 more source
Sclerosing Orbital Inflammation Caused by Leishmania braziliensis [PDF]
The American Society of Tropical Medicine and Hygiene, 2017 Orbital biopsy of nonspecific orbital inflammation, commonly referred to as “orbital pseudotumor,” typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital ...
Antonio Augusto V, Cruz +6 more
openaire +2 more sources
Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer
Immunology, Volume 178, Issue 3, Page 377-386, July 2026.Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros +5 more
wiley +1 more source
Iranian Journal of Parasitology, 2021 Background: We aimed to determine the cellular recruitment (leukocyte rolling and adhesion) by which the Leishmania (Viannia) braziliensis, L. (Leishmania) amazonensis, and L. (Leishmania) major species in the mesenteric microcirculation of BALB/c mice.
Herintha Coeto Neitzke-Abreu +9 more
doaj
Frontiers in Cellular and Infection Microbiology, 2022 Patients with cutaneous leishmaniasis (CL) due to Leishmania braziliensis infection have an exacerbated inflammatory response associated with tissue damage and ulcer development.
Maurício T. Nascimento +22 more
doaj +1 more source
Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi
ChemMedChem, Volume 21, Issue 9, 14 May 2026.New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira +7 more
wiley +1 more source
Veterinaria Italiana, 2023 Euthanasia of animals is not accepted as a control for cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis and drugs used in humans for the treatment of leishmaniasis are not allowed for animals in Brazil.
Marcos Santos Zanini +6 more
doaj +1 more source
Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite
Protein Science, Volume 35, Issue 5, May 2026.Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose +4 more
wiley +1 more source
Peptides as a Therapeutic Alternative Against Leishmaniasis: A Scoping Review
Chemical Biology &Drug Design, Volume 107, Issue 5, May 2026.This scoping review of 79 studies identified 231 antimicrobial peptides with anti‐Leishmania activity, including natural‐derived and synthetic peptides (inspired by natural sources or developed through rational design). Most were evaluated in vitro against promastigote and/or amastigote forms, with synthetic peptides showing a more promising effect ...
Maria Eduarda da Veiga Oliveira +3 more
wiley +1 more source