Results 41 to 50 of about 10,019 (209)

Histone post-translational modifications of Leishmania braziliensis. [PDF]

Sci Data
Histone post-translational modifications (hPTMs) constitute an epigenetic mechanism that plays a fundamental role in the regulation of gene expression in eukaryotic cells. In trypanosomatid parasites, such as Trypanosoma brucei, T. cruzi and Leishmania spp., gene regulation occurs mainly at the post-transcriptional level.
de Almeida RF, Fernandes M, Figueiredo FB, de Godoy LMF.   +3 more
europepmc   +4 more sources

Leishmaniasis in Bolivia: II. The involvement of Psychodopygus yucumensis and Psychodopygus llanosmartinsi in the selvatic transmission cycle of Leishmania braziliensis braziliensis in a lowland subandean region

Memorias do Instituto Oswaldo Cruz, 1986
An epidemiological survey of the vectors of cutaneous leishmaniasis ("espúndia" type) was caried out in the Alto Beni region of Bolivia, an area of Andean foothills at the Eastern limit of the Amazonian lowlands. The climate is typical wet tropical (15ºS
F. Le Pont, Philippe Desjeux
doaj   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Infecção natural por Leishmania sp. em flebotomíneos capturados no foco de transmissão de Leishmaniose Tegumentar Americana no município de Piçarras, litoral norte do Estado de Santa Catarina e identificação específica do parasito em amostras clínicas e em cepas isoladas de pacientes. [PDF]

, 2008
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.As Leishmanioses são doenças infecto-parasitárias causadas por protozoários do gênero Leishmania, que acometem cerca de 12 milhões de indivíduos em 88 países
Bittencourt, Ize de Aguiar
core  

Anti-leishmanial Activity of Justicidone and its Synthetic Precursors

Natural Product Communications, 2007
Justicidone, a C-5, C-8 dioxo-lignan of the arylnaphthalene type isolated from Justicia hyssopifolia, and its synthetic precursors were tested for the activity against Leishmania braziliensis and Leishmania amazonensis promastigotes in vitro. Justicidone
Carlos José Boluda, José Piñero, Marialina Romero, María Gabriela Cabrera-Serra, Basilio Valladares, Zulma Aragón, Hermelo López, José A. Pérez, Juan M. Trujillo   +8 more
doaj   +1 more source

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

Immunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros, Gabriel Augusto Leite, Arthur Gomes de Andrade, Maria Danielma dos Santos Reis, Luiz Henrique Agra Cavalcante‐Silva, Marvin Paulo Lins   +5 more
wiley   +1 more source

Clonagem e expressão da enzina tripanotiona redutase de Leishmania braziliensis e atividade leishmanicida de chalconas [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Programa de Pós-graduação em Biotecnologia, Florianópolis, 2011O presente estudo teve por objetivo avaliar atividade leishmanicida in vitro de chalconas trimetoxiladas contra formas ...
Nunes, Rebeca Körting
core  

Leishmania braziliensis exosomes activate human macrophages to produce proinflammatory mediators [PDF]

, 2023
Exosomes, organelles measuring 30-200nm, are secreted by various cell types. Leishmania exosomes consist of many proteins, including heat shock proteins, annexins, Glycoprotein 63, proteins exerting signaling activity and those containing mRNA and miRNA.
Edgar M. Carvalho, Phillip Scott, Mauricio T. Nascimento, Rodrigo C. O. Sanches, Mateus Aoki, Lucas P. Carvalho, Dalila L. Zanette, Sérgio C. Oliveira, Fabio C. Peixoto, Thiago M. Cardoso   +9 more
core   +1 more source

AISLAMIENTO DE Leishmania brazilienzis braziliensis en Proechimys sp. CAPTURADO EN EL RIO NAPO, LORETO - PERU

, 1991
Se reporta el hallazgo de Proechimys sp. procedente del río Napo, provincia de Maynas, departamento de Loreto, Perú, infectado con Leishmania braziliensis braziiensis.
BRAGA-VELA, Janeth, BRAGA-RIBEIRO, Roseli, VIENA-DEL AGUILA, Máximo, GARCÍA-MARTÍNEZ, Edward   +3 more
core   +2 more sources

Clonal variation within a mucosal isolate derived from a patient with Leishmania (Viannia) braziliensis infection Variação clonal de um isolado derivado de um paciente com infecção mucosa pela Leishmania (Viannia) braziliensis

Revista do Instituto de Medicina Tropical de São Paulo, 1991
Three isolates over 5 years from a patient with persistent relapsing mucosal leishmaniasis due to Leishmania (Viannia) braziliensis and 7 clones from one of these isolates were studied by zymodemes and scrodemes analysis.
César Augusto Cuba-Cuba, David Evans, Ana de Cassia Rosa, Philip Davis Marsden   +3 more
doaj   +1 more source