Results 61 to 70 of about 6,448 (173)

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto, Gustavo Clauss, Jennyfer Castro, Marcus S. A. Garcia, Natasha M. Cassani, Bruna C. Sandim, Ana Laura C. Oliveira, Stephanie P. B. Reyes, Nádija N. P. da Silva, Fillipe V. Rocha, Ana C. G. Jardim, Danilo C. Miguel, Camilla Abbehausen   +12 more
wiley   +1 more source

Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition

Frontiers in Microbiology, 2017
Inositol phosphorylceramide (IPC), the major sphingolipid in the genus Leishmania but not found in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis.
Erica V. De Castro Levatti, Marcos S. Toledo, Renata Watanabe Costa, Diana Bahia, Diana Bahia, Renato A. Mortara, Helio K. Takahashi, Anita H. Straus   +7 more
doaj   +1 more source

Oral Treatment With Heat Shock Protein 65‐Producing Lactococcus lactis Induces Regulatory T Cells, Modulating Inflammatory Response in Leishmania braziliensis Infection

Immunology, Volume 177, Issue 1, Page 59-69, January 2026.
Oral treatment with HSP65‐producing Lactococcus lactis after Leishmania braziliensis infection modulates inflammation by promoting lesion resolution through increased IL‐10 production and expansion of regulatory T cells. These findings highlight the potential of oral tolerance induction as a promising therapeutic strategy for chronic inflammatory ...
Camila Mattos Andrade, Ítalo da Silva Gonçalves, Maria Luiza das Neves Nascimento, Washington Luís Conrado Santos, Vasco Ariston Azevedo, Deborah Bittencourt Mothé, Juliana Perrone Menezes Fullam, Patrícia Sampaio Tavares Veras, Natalia Machado Tavares, Tatiani Uceli Maioli, Ana Maria Caetano Faria, Cláudia Ida Brodskyn   +11 more
wiley   +1 more source

El cultivo "in vitro" como instrumento práctico para el diagnóstico y aislamiento primario de Leishmania braziliensis braziliensis. 2. Estudios en pacientes de áreas endémicas

Revista do Instituto de Medicina Tropical de São Paulo, 1986
El cultivo "in vitro" de Leishmania braziliensis braziliensis constituye un método útil en el trabajo de campo, para el aislamiento primario de ésta subes-pécie de Leishmania.
C. A. Cuba Cuba, E. M. Netto, J. L. M. Costa, A. C. Barreto, P. D. Marsden   +4 more
doaj   +1 more source

Dogs as Reservoirs forLeishmania braziliensis

Emerging Infectious Diseases, 2011
To the Editor: I have read the review by Sousa and Pearson (1), which provides a fascinating historical account of the Great Drought and the smallpox epidemic of the 1870s and their association with the emergence of cutaneous leishmaniasis in Ceara, Brazil.
openaire   +2 more sources

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source

Mechanisms of Immune Evasion, Dissemination, and Persistence in Leishmania amazonensis Infection

Parasite Immunology, Volume 48, Issue 1, January 2026.
ABSTRACT Leishmania amazonensis is one of the etiological agents of cutaneous leishmaniasis in its localised form. Moreover, this parasite can cause more severe disease conditions, such as diffuse and disseminated cutaneous leishmaniasis. The development of more severe clinical manifestations is associated with the parasite's ability to establish a ...
Arieli Bernardo Portugal, Renato Augusto DaMatta, Edézio Ferreira da Cunha Júnior, João Luiz Mendes Wanderley   +3 more
wiley   +1 more source

American cutaneous leishmaniasis in dogs from an endemic urban area in Cianorte municipality, Paraná State, Brazil

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
American cutaneous leishmaniasis (ACL) was investigated in dogs from an urban endemic area in Cianorte, Paraná state, Brazil. Of 169 studied dogs, none presented suspected ACL lesions.
DA Cerino, J Veloso, TF Perles, PD Zanzarini, MVC Lonardoni, TGV Silveira   +5 more
doaj   +1 more source

Capacidad infectiva de promastigotes en fase estacionaria de leishmania (viannia) braziliensis y leishmania (viannia) peruviana, en línea celular dh82

Revista Peruana de Medicina Experimental y Salud Pública
Objetivos. Determinar la capacidad infectiva de los promastigotes de Leishmania (V.) peruviana y Leishmania (V.) braziliensis en la línea celular macrófago-monocítica de Canis familiaris DH82. Materiales y métodos.
Karen Daphne Calvay-Sánchez, Nyshon Máximo Rojas-Palomino, Aidé Clorinda Sandoval-Juarez, Alberto Cisneros-Tarmeño, Cristian Obregón-Cahuaya, Gloria Sonia Minaya-Gómez   +5 more
doaj   +2 more sources

Achievement of constitutive fluorescent pLEXSY-egfp Leishmania braziliensis and its application as an alternative method for drug screening in vitro

Memorias do Instituto Oswaldo Cruz
BACKGROUND Gene reporter-fluorescent cells have emerged as alternative method for drug screening. OBJECTIVE Achievement of constitutive expression of fluorescent protein GFP by Leishmania braziliensis as alternative method for drug screening. METHODS
Matheus Silva e Bastos, Luciana Ângelo de Souza, Thiago Souza Onofre, Abelardo Silva Júnior, Márcia Rogéria de Almeida, Gustavo Costa Bressan, Juliana Lopes Rangel Fietto   +6 more
doaj   +1 more source