Results 51 to 60 of about 15,890 (220)

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto, Gustavo Clauss, Jennyfer Castro, Marcus S. A. Garcia, Natasha M. Cassani, Bruna C. Sandim, Ana Laura C. Oliveira, Stephanie P. B. Reyes, Nádija N. P. da Silva, Fillipe V. Rocha, Ana C. G. Jardim, Danilo C. Miguel, Camilla Abbehausen   +12 more
wiley   +1 more source

Leukocyte Behavior in Mesenteric Microcirculation upon Experimental By Leishmania Spp. in BALB/c Mice

Iranian Journal of Parasitology, 2021
Background: We aimed to determine the cellular recruitment (leukocyte rolling and adhesion) by which the Leishmania (Viannia) braziliensis, L. (Leishmania) amazonensis, and L. (Leishmania) major species in the mesenteric microcirculation of BALB/c mice.
Herintha Coeto Neitzke-Abreu, Rhuan Carlos Souza Caetano, Kárin Rosi Reinhold-Castro, Manoel Sebastião da Costa Lima-Junior, Wagner José Tenório dos Santos, Gessilda de Alcantara Nogueira de Melo, Roberto Kenji Nakamura Cuman, Sandra Mara Alessi Aristides, Thais Gomes Verzignassi Silveira, Maria Valdrinez Campana Lonardoni   +9 more
doaj  

Leishmania braziliensis prostaglandin F2α synthase impacts host infection [PDF]

Parasites & Vectors, 2020
AbstractBackgroundProstaglandins (PG) are lipid mediators derived from arachidonic acid metabolism. They are involved in cellular processes such as inflammation and tissue homeostasis. PG production is not restricted to multicellular organisms. Trypanosomatids also synthesize several metabolites of arachidonic acid.
Alves-Ferreira, Eliza Vanessa Carneiro, Ferreira, Tiago Rodrigues, Walrad, Pegine, Kaye, Paul M, Cruz, Angela Kaysel   +4 more
openaire   +5 more sources

Pioglitazone, a Peroxisome Proliferator-Activated Receptor-γ Agonist, Downregulates the Inflammatory Response in Cutaneous Leishmaniasis Patients Without Interfering in Leishmania braziliensis Killing by Monocytes

Frontiers in Cellular and Infection Microbiology, 2022
Patients with cutaneous leishmaniasis (CL) due to Leishmania braziliensis infection have an exacerbated inflammatory response associated with tissue damage and ulcer development.
Maurício T. Nascimento, Maurício T. Nascimento, Maurício T. Nascimento, Ravena S. O. Cordeiro, Cayo Abreu, Camila P. Santos, Camila P. Santos, Fábio Peixoto, Fábio Peixoto, Gabriela A. Duarte, Thiago Cardoso, Thiago Cardoso, Camila I. de Oliveira, Camila I. de Oliveira, Camila I. de Oliveira, Edgar M. Carvalho, Edgar M. Carvalho, Edgar M. Carvalho, Edgar M. Carvalho, Lucas P. Carvalho, Lucas P. Carvalho, Lucas P. Carvalho, Lucas P. Carvalho   +22 more
doaj   +1 more source

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source

Mechanisms of Immune Evasion, Dissemination, and Persistence in Leishmania amazonensis Infection

Parasite Immunology, Volume 48, Issue 1, January 2026.
ABSTRACT Leishmania amazonensis is one of the etiological agents of cutaneous leishmaniasis in its localised form. Moreover, this parasite can cause more severe disease conditions, such as diffuse and disseminated cutaneous leishmaniasis. The development of more severe clinical manifestations is associated with the parasite's ability to establish a ...
Arieli Bernardo Portugal, Renato Augusto DaMatta, Edézio Ferreira da Cunha Júnior, João Luiz Mendes Wanderley   +3 more
wiley   +1 more source

Treatment of canine cutaneous leishmaniasis by Leishmania (Viannia) braziliensis in dogs with furazolidone and β-cyclodextrin: case report.

Veterinaria Italiana, 2023
Euthanasia of animals is not accepted as a control for cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis and drugs used in humans for the treatment of leishmaniasis are not allowed for animals in Brazil.
Marcos Santos Zanini, Larissa Ataíde Siqueira, Yuri Vieira Almeida, Laisa Savergnini Poleze, Dante Gnecco Zanini , Roberto Ramos Sobreira, Ana Paula Madureira   +6 more
doaj   +1 more source

Leishmania-specific surface antigens show sub-genus sequence variation and immune recognition. [PDF]

, 2010
A family of hydrophilic acylated surface (HASP) proteins, containing extensive and variant amino acid repeats, is expressed at the plasma membrane in infective extracellular (metacyclic) and intracellular (amastigote) stages of Old World Leishmania ...
Depledge, DP, Hodgkinson, MR, Jackson, AP, Ma, S, MacLean, LM, Smith, BA, Smith, DF, Uliana, SR   +7 more
core  

Comparative genomic analysis of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensis [PDF]

, 2015
BACKGROUND: The Leishmania (Viannia) braziliensis complex is responsible for most cases of New World tegumentary leishmaniasis. This complex includes two closely related species but with different geographic distribution and disease phenotypes, L.
Baldeviano, G. Christian, Baptista, Rodrigo P, Bartholomeu, Daniella C, Bastien, Patrick, Beverley, Stephen M, Dobson, Deborah E, Gerbasi, Robert V, Lescano, Andres G, Pratlong, Francine, Reis-Cunha, Joao L, Rodrigues-Luiz, Gabriela F, Valdivia, Hugo O   +11 more
core   +7 more sources

Health Benefits and Therapeutic Potential of Quercetin

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source