Results 61 to 70 of about 15,890 (220)

Library of Seleno-Compounds as Novel Agents against Leishmania Species [PDF]

, 2017
The in vitro leishmanicidal activities of a series of 48 recently synthesized selenium derivatives against Leishmania infantum and Leishmania braziliensis parasites were tested using promastigotes and intracellular amastigote forms.
Alcolea-Devesa, V. (Verónica), Diaz, M. (Marta), Espuelas, S. (Socorro), Gutierrez-Sanchez, R. (Ramon), Marin, C. (Clotilde), Martin-Escolano, R. (Ruben), Martin-Montes, A.(Alvaro), Moreno-Amatria, E. (Esther), Plano-Amatriain, D. (Daniel), Pérez-Silanes, S. (Silvia), Sanchez-Moreno, M. (Manuel), Sanmartin-Grijalba, C. (Carmen)   +11 more
core   +1 more source

Piplartine as an Innovative Natural Product With Dual Antiparasitic and Immunomodulatory Actions

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Neglected tropical diseases (NTDs) remain a major global health burden, disproportionately affecting low‐ and middle‐income regions and demanding innovative therapeutic strategies. This review summarizes current evidence on piplartine (piperlongumine), a naturally occurring amide from Piper species with broad antiparasitic and immunomodulatory ...
Lucas Fukui-Silva, Felipe C. R. de Souza, Camila S. Amorim, Josué de Moraes, Poorani Gurumallesh Prabu   +4 more
wiley   +1 more source

Development of Colombian isolates of Leishmania (Viannia) panamensis, Le. (V.) guyanensis and Le. (V.) braziliensis in the sandfly Lutzomyia intermedia (Lutz & Neiva, 1912) under experimental conditions

Memorias do Instituto Oswaldo Cruz, 1993
The development of Colombian Leishmania species of the subgenus Viannia in Lutzomyia intermedia was similar to that observed with Brazilian Le. (V.) braziliensis: colonization of the pylorus by paramastigotes; promastigotes in the midgut and massive ...
Elizabeth Ferreira Rangel, Bruno L. Travi, André F. Barbosa, James Montoya   +3 more
doaj   +1 more source

Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues, Emilha Uzum Papaya, Fernanda da Silva, Carla Cardozo Pinto de Arruda, Edson Lucas dos Santos, Kely de Picoli Souza, Carlos Alexandre Carollo   +6 more
wiley   +1 more source

Serological reactivity of different antigenic preparations of Leishmania (Leishmania) amazonensis and the Leishmania braziliensis complex Reatividade sorológica frente a diferentes preparações antigênicas de Leishmania (Leishmania) amazonensis e do complexo Leishmania braziliensis

Revista da Sociedade Brasileira de Medicina Tropical, 2008
Total antigen from Leishmania (Leishmania) amazonensis and isolates from the Leishmania braziliensis complex, along with their respective antigenic fractions obtained by affinity chromatography on concanavalin-A-Sepharose and jacalin-agarose columns ...
Adriano Gomes-Silva, Maria Aparecida Souza, Sandra Regina Afonso-Cardoso, Lívia Resende Andrade, Reynaldo Dietze, Elenice Lemos, Alejandro Belli, Silvio Favoreto Júnior, Marcelo Simão Ferreira   +8 more
doaj   +1 more source

Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis. [PDF]

, 2017
Leishmania parasites utilize adaptive evasion mechanisms in infected macrophages to overcome host defenses and proliferate. We report here that the PERK/eIF2α/ATF4 signaling branch of the integrated endoplasmic reticulum stress response (IERSR) is ...
Aktas, B.H., Calegari-Silva, T.C., Cavalcanti, Á., Dias-Teixeira, K.L., Fasel, N., Gomes, C.M., Lopes, U.G., Medina, J.M., Pereira, RMS, Real, F., Santana, AKM, Silva, J.S., Teteo, N., Vivarini, Á.C.   +13 more
core   +3 more sources

Mapping the Burden of Tegumentary Leishmaniasis in South America: A Systematic Review and Meta‐Analysis

Tropical Medicine &International Health, Volume 30, Issue 12, Page 1261-1268, December 2025.
ABSTRACT Introduction In recent years, the global burden of tegumentary leishmaniasis (TL) has significantly increased in the Americas. Objective To estimate the prevalence of TL in South America based on publications from the past 13 years. Methods Three databases were searched, and articles were selected based on inclusion criteria and methodological
Sérgio Caldas, Job Alves de Souza Filho, Janete Soares Coelho Santos, Felipe Campos de Melo Iani, Cristiane Faria de Oliveira Scarponi   +4 more
wiley   +1 more source

Leishmania (Viannia) braziliensis growth in vitro culture relies more on folic acid availability than Leihsmania (Leishmania) amazonensis

Memorias do Instituto Oswaldo Cruz, 2005
We compared the in vitro growth of promastigotes from two Leishmania species in TC-100 and Schneider media. Leishmania (Leishmania) amazonensis replication rates were similar in both tissue culture media and reached maximum rates by 48 h.
Andrea Niño, Marcela Camacho
doaj   +1 more source

Influence of Leishmania (Viannia) Species on the Response to Antimonial Treatment in Patients with American Tegumentary Leishmaniasis [PDF]

, 2017
Background. Pentavalent antimonials (SbV) are the first-line chemotherapy for American tegumentary leishmaniasis (ATL). There are, however, reports of the occurrence of treatment failure with these drugs.
Adaui, Vanessa, Arevalo, Jorge, Chappuis, Francois, De Doncker, Simonne, Dujardin, Jean-Claude, Lazo, Marcela, Llanos-Cuentas, Alejandro, Loayza-Muro, Raúl, Maurer, Anne, Miranda-Verástegui, César, Ramirez, Luis, Tulliano, Gianfranco, Zimic, Mirko   +12 more
core  

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source