Results 101 to 110 of about 29,719 (208)

Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]

, 2009
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Aebischer, Toni, Blackburn, Clare, Brand, Janko, Brinkmann, Volker, Hoffmann, Kirstin, Lippuner, Christoph, Paape, Daniel, Paterou, Athina, Richardson, Melville, Smith, Andrew   +9 more
core   +1 more source

Comparative study of the biological behaviour in hamster of two isolates of leishmania characterized respectively as L. major-like and L. donovani

Revista do Instituto de Medicina Tropical de São Paulo, 1988
Hamster inoculated intraperitoneally with 1 x 10(7) parasites of L. donovani and L. major-like of the New World were studied in groups of 15, 30, 60 and 90 days of infection. The parasite load and density showed progressive increase with the evolution of
M. I. S. Duarte, M. D. Laurenti, H. F. Andrade Jr., C. E. P. Corbett   +3 more
doaj   +1 more source

Effective Tetradentate Compound Complexes against Leishmania spp. that Act on Critical Enzymatic Pathways of These Parasites

Molecules, 2018
The spectrum and efficacy of available antileishmanial drugs is limited. In the present work we evaluated in vitro the antiproliferative activity of 11 compounds based on tetradentate polyamines compounds against three Leishmania species (L. braziliensis,
Kristína Urbanová, Inmaculada Ramírez-Macías, Rubén Martín-Escolano, María José Rosales, Olaf Cussó, Joan Serrano, Anna Company, Manuel Sánchez-Moreno, Miquel Costas, Xavi Ribas, Clotilde Marín   +10 more
doaj   +1 more source

Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy.

, 2007
Leishmaniasis is a geographically widespread severe disease, with an increasing incidence of two million cases per year and 350 million people from 88 countries at risk. The causative agents are species of Leishmania, a protozoan flagellate.
Ayala, Francisco J, Chocholová, Eva, Dedet, Jean-Pierre, Dujardin, Jean-Claude, Haralambous, Christos, Horák, Ales, Jirků, Milan, Kuhls, Katrin, Lukes, Julius, Mauricio, Isabel L, Miles, Michael A, Oborník, Miroslav, Pratlong, Francine, Schönian, Gabriele, Soteriadou, Ketty, Tintaya, K Wilber Quispe   +15 more
core   +2 more sources

Management of trypanosomiasis and leishmaniasis [PDF]

, 2012
<p>Background: The current treatments for human African trypanosomiasis (HAT), Chagas disease and leishmaniasis (collectively referred to as the kinetoplastid diseases) are far from ideal but, for some, there has been significant recent progress ...
Alsford, Alvar, Alvar, Barrett, Barrett, Ben Salah, Berman, Bern, Brun, Brun, Burri, Chappuis, Coura, Croft, Croft, El-Sayed, Frearson, Hailu, Jacobs, Jacobs, Le Loup, Lessa, M. P. Barrett, Miranda-Verastegui, Paine, Pinazo, Priotto, Rassi, Reithinger, Rodgers, S. L. Croft, Stuart, Sundar, Sundar, Sundar, Sundar, Torreele, Vanhollebeke, Vincent, Voogd   +39 more
core   +2 more sources

The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation.

, 2010
OBJECTIVE: Elevated serum levels of the acute-phase protein serum amyloid A (SAA) are a marker for active rheumatoid arthritis (RA), and SAA can also be found in the tissues of patients with active RA.
Björkman, Lena, Bylund, Johan, Dahlgren, Claes, Karlsson, Anna, Raynes, John G, Shah, Chandrabala   +5 more
core   +1 more source

Evolutionary history of Leishmania killicki (synonymous Leishmania tropica) and taxonomic implications [PDF]

, 2015
Background: Leishmania (L.) killicki is responsible for the chronic cutaneous leishmaniasis. The taxonomic status of this parasite is still not well defined. It was suggested on one hand to include this taxon within L.
Babba, Hamouda, BaÑuls, Anne- Laure, Chaara, Dhekra, Dedet, Jean-Pierre, El baidouri, Fouad, Haouas, Najoua, Harrat, Zoubir, Jaouadi, Kaouther, Lami, Patrick, Pratlong, Francine, Ravel, Christophe, Talignani, Loïc   +11 more
core   +2 more sources

Transcription of toll-like receptors 2, 3, 4 and 9, FoxP3 and Th17 cytokines in a susceptible experimental model of canine Leishmania infantum infection [PDF]

, 2015
Canine leishmaniosis (CanL) due to Leishmania infantum is a chronic zoonotic systemic disease resulting from complex interactions between protozoa and the canine immune system.
A Ives, A Rodriguez, A Rodriguez-Cortes, A Rodriguez-Cortes, A Rodriguez-Cortes, AB Reis, AK House, AK Rai, Alhelí Rodríguez-Cortés, AM Elassad, BL Travi, C Gallego, C Gonzalez-Lombana, C Maia, C Maia, C Riera, CE O'Neil, CF Alves, CR Engwerda, D Menezes-Souza, D Sacks, D Strauss-Ayali, DA Vargas-Inchaustegui, Damer P. Blake, E Bourreau, F Chappuis, FF Tuon, FF Tuon, G Baneth, GA Cezario, GD Melo, GK Katara, GM Santos-Gomes, H Kumar, IR Peters, J Alvar, J Liese, J Moreno, J Sano, JF Flandin, JM Ehrchen, Jordi Alberola, K Ghosh, K Wolk, Karin Allenspach, KL Silva, L Solano-Gallego, L Solano-Gallego, Laia Solano-Gallego, LM Melo, LP Carvalho, MA Almeida, MG Pitta, MJ de Veer, MJ Rica-Capela, MM Figueiredo, MM Figueiredo, MS Nascimento, N Peters, O Courtenay, O Francino, OA Garden, OR Rodrigues, P Desjeux, P Holzmuller, P Kropf, R Kumar, S Lopez Kostka, S Nylen, S Schmitz, S Tiwananthagorn, S Tolouei, SH Wood, Shazia Hosein, T Korn, TM Castilho, VL da Matta, VS Boaventura, VS Raman, Y Belkaid, Yara M. Traub-Csekö, ZK Peng   +81 more
core   +4 more sources

A neglected disease of humans: a new focus of visceral leishmaniasis in Bakool, Somalia. [PDF]

, 2008
Visceral leishmaniasis (VL) was observed in children in Bakool region, Somalia, an area where VL has not been reported before. We describe the extent of the problem in this war- and famine-stricken area.
Boelaert, M, Dujardin, J C, Jacquet, D, Marlet, M V L, Quispe, K W, Wuillaume, F   +5 more
core   +1 more source

The recombinant cysteine proteinase B (CPB) from Leishmania braziliensis and its domains: promising antigens for serodiagnosis of cutaneous and visceral leishmaniasis in dogs. [PDF]

, 2019
Leishmaniasis represents a group of parasitic diseases caused by a protozoan of the genus Leishmania and is widely distributed in tropical and subtropical regions.
Basombrío, Manuel Alberto, Bivona, Augusto Ernesto, Cardoso Landaburu, Alejandro Cesar, Cazorla, Silvia Ines, Cerny, Natacha, Czentner Colomo, Lucas, Estevez, José Octavio, Malchiodi, Emilio Luis, Marco, Jorge Diego, Nevot, María Cecilia, Sanchez Alberti, Andrés   +10 more
core   +1 more source