Results 101 to 110 of about 35,225 (252)

When Hepatitis Masks Visceral Leishmaniasis: A Case of Secondary HLH in a Low‐Endemic Region

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Visceral leishmaniasis (VL)–associated hemophagocytic lymphohistiocytosis (HLH) is a rare but life‐threatening hyperinflammatory syndrome. Diagnosis is often challenging due to overlapping clinical features, especially in low‐endemic regions, where VL is not initially suspected.
Chernet T. Mengistie, Biruk T. Mengistie, Temesgen H. Gebremeskel, Thomas M. Muluneh, Rediet G. Kebede   +4 more
wiley   +1 more source

Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy [PDF]

, 2017
Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various ...
Ali, Juma A.M., Alzahrani, Khalid J.H., Barrett, Michael P., Creek, Darren J., De Koning, Harry P., Eze, Anthonius A., Looi, Wan Limm, Tagoe, Daniel N.A.   +7 more
core   +2 more sources

Can cutaneous leishmaniasis provoke a resurgence of kala-azar in the Indian subcontinent?

BMC Infectious Diseases
Background The ongoing kala-azar elimination program in Nepal is based on the assumption of anthroponotic transmission of the protozoan parasite Leishmania donovani. This parasite species was recently also found in lesions of cutaneous leishmaniasis (CL)
Narayan Raj Bhattarai, Keshav Rai, Surendra Uranw, Dhan Keshar Khadka, Basudha Khanal, Gokarna Dahal, Sushmita Pradhan, Sushil Dhakal, Pieter Monsieurs, Tanyth de Gooyer, Kristien Cloots, Epco Hasker, Gert Van der Auwera   +12 more
doaj   +1 more source

Application of kDNA as a molecular marker to analyse Leishmania infantum diversity in Portugal.

, 2006
Around the Mediterranean basin Leishmania infantum is an important parasite causing canine leishmaniasis and visceral and cutaneous clinical forms in both immunocompetent and immunocompromised humans.
Almeida, Ana, Campino, Lenea, Cortes, Sofia, Cristovão, José Manuel, Dedet, Jean Pierre, Mauricio, Isabel, Pratlong, Francine   +6 more
core   +1 more source

Current Perspectives on Leishmaniasis

Journal of Gandaki Medical College, 2019
No abstract available.
KR Reddy
doaj   +1 more source

Author response for "The catalytic core of Leishmania donovani RECQ helicase unwinds a wide spectrum of DNA substrates and is stimulated by replication protein A"

, 2021
Kumari Shikha, Gugulothu Sriram Bharath, Swagata Mukhopadhyay, Mayukh Chakraborty, Susmita Ghosh, Suparna Khatun, Debajyoti De, Amar Nath Gupta, Agneyo Ganguly   +8 more
openalex   +1 more source

Comparative study of the biological behaviour in hamster of two isolates of leishmania characterized respectively as L. major-like and L. donovani

Revista do Instituto de Medicina Tropical de São Paulo, 1988
Hamster inoculated intraperitoneally with 1 x 10(7) parasites of L. donovani and L. major-like of the New World were studied in groups of 15, 30, 60 and 90 days of infection. The parasite load and density showed progressive increase with the evolution of
M. I. S. Duarte, M. D. Laurenti, H. F. Andrade Jr., C. E. P. Corbett   +3 more
doaj   +1 more source

Modulation of the Innate and the Adaptive Immune Expression of THP1 Cell Line Following Infection with Leishmania L. Major and L. Donovani Isolates from Sudanese Patients

, 2022
Amal F. Al Dawi, Sababil S. Ali, Dalia. M Ahmed, Maowia M. Mukhtar   +3 more
openalex   +1 more source

Glycobiology of Leishmania donovani.

The Indian journal of medical research, 2006
Leishmania donovani, the causative organism of visceral leishmaniasis (VL) is one of the deadliest of the entire known Leishmania species. This protozoan parasite displays immense adaptability to survive under extremely harsh conditions. Cell surface glycoconjugates play a pivotal role in parasite virulence and infectivity.
Sumi, Mukhopadhyay, Chitra, Mandal
openaire   +1 more source

Effective Tetradentate Compound Complexes against Leishmania spp. that Act on Critical Enzymatic Pathways of These Parasites

Molecules, 2018
The spectrum and efficacy of available antileishmanial drugs is limited. In the present work we evaluated in vitro the antiproliferative activity of 11 compounds based on tetradentate polyamines compounds against three Leishmania species (L. braziliensis,
Kristína Urbanová, Inmaculada Ramírez-Macías, Rubén Martín-Escolano, María José Rosales, Olaf Cussó, Joan Serrano, Anna Company, Manuel Sánchez-Moreno, Miquel Costas, Xavi Ribas, Clotilde Marín   +10 more
doaj   +1 more source