Results 71 to 80 of about 13,690 (178)
Global genome diversity of the Leishmania donovani complex
eLife, 2020 Protozoan parasites of the Leishmania donovani complex – L. donovani and L. infantum – cause the fatal disease visceral leishmaniasis. We present the first comprehensive genome-wide global study, with 151 cultured field isolates representing most of the ...
Susanne U Franssen +20 more
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Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite
Protein Science, Volume 35, Issue 5, May 2026.Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose +4 more
wiley +1 more source
Can cutaneous leishmaniasis provoke a resurgence of kala-azar in the Indian subcontinent?
BMC Infectious DiseasesBackground The ongoing kala-azar elimination program in Nepal is based on the assumption of anthroponotic transmission of the protozoan parasite Leishmania donovani. This parasite species was recently also found in lesions of cutaneous leishmaniasis (CL)
Narayan Raj Bhattarai +12 more
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Glycobiology of Leishmania donovani.
The Indian journal of medical research, 2006 Leishmania donovani, the causative organism of visceral leishmaniasis (VL) is one of the deadliest of the entire known Leishmania species. This protozoan parasite displays immense adaptability to survive under extremely harsh conditions. Cell surface glycoconjugates play a pivotal role in parasite virulence and infectivity.
Sumi, Mukhopadhyay, Chitra, Mandal
openaire +1 more source
Current Perspectives on Leishmaniasis
Journal of Gandaki Medical College, 2019 No abstract available.
KR Reddy
doaj +1 more source
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 1990 The need for a reliable method for the immunological diagnosis of kala-azar is imperative. Leishmania donovani donovani and L. donovani chagasi culture promastigotes were compared as antigens in a direct agglutination test (DAT) for the diagnosis of visceral leishmaniasis in Brazil.
C R, Andrade +3 more
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Revista do Instituto de Medicina Tropical de São Paulo, 1988 Hamster inoculated intraperitoneally with 1 x 10(7) parasites of L. donovani and L. major-like of the New World were studied in groups of 15, 30, 60 and 90 days of infection. The parasite load and density showed progressive increase with the evolution of
M. I. S. Duarte +3 more
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Molecules, 2018 The spectrum and efficacy of available antileishmanial drugs is limited. In the present work we evaluated in vitro the antiproliferative activity of 11 compounds based on tetradentate polyamines compounds against three Leishmania species (L. braziliensis,
Kristína Urbanová +10 more
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