Results 81 to 90 of about 36,027 (251)

Follow-up monitoring in a cat with leishmaniosis and coinfections with Hepatozoon felis and ‘Candidatus Mycoplasma haemominutum’ [PDF]

, 2017
Case summary A 6-year-old female neutered domestic shorthair cat from Cyprus was presented with multiple ulcerated skin nodules. Cytology and histopathology of the lesions revealed granulomatous dermatitis with intracytoplasmic organisms, consistent ...
Attipa, C, Baneth, G, Brooks-Brownlie, H, Martínez-Orellana, P, Nachum-Biala, Y, Neofytou, K, Solano-Gallego, L, Tasker, S, Yiapanis, C   +8 more
core   +6 more sources

Concurrent iridociliary adenoma and haemorrhagic uveal cysts causing rapid intraocular mass progression in a dog

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 6‐year‐old, mixed‐breed dog was referred for evaluation of a red, non‐painful right eye. Examination revealed a well‐circumscribed, lobulated, reddish mass in the anterior chamber, initially presumed to be a benign haematocyst. Despite the non‐aggressive appearance and lack of pain or inflammation, the mass demonstrated rapid enlargement ...
Lionel Sebbag, Nili Kahane, Havi Sarfaty
wiley   +1 more source

Control of Bovicola equi infestation in a herd of horses using an environmentally sustainable treatment protocol

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract In March 2024, a Slovenian warmblood gelding presented with severe pruritus and skin lesions throughout its head, neck and around the base of the tail. The owners had observed increased pruritus in multiple animals within the herd. After careful examination, Bovicola equi were found in all five horses, but not the pony.
Petra Bandelj, Andrew Peregrine, Anja Joachim   +2 more
wiley   +1 more source

Structures of the Leishmania infantum polymerase beta [PDF]

DNA Repair, 2014
Protozoans of the genus Leishmania, the pathogenic agent causing leishmaniasis, encode the family X DNA polymerase Li Pol β. Here, we report the first crystal structures of Li Pol β. Our pre- and post-catalytic structures show that the polymerase adopts the common family X DNA polymerase fold. However, in contrast to other family X DNA polymerases, the
Mejía Edison, Burak, Matthew, Alonso, Ana, Larraga, Vicente, Kunkel, Thomas A., Bebenek, Katarzyna, García-Díaz, Miguel   +6 more
openaire   +3 more sources

Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory

Immunology, Volume 177, Issue 2, Page 254-269, February 2026.
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco, Itziar Martín‐Ruiz, Sarai Araujo‐Aris, Diego Barriales, Janire Castelo, Leire Egia‐Mendikute, Monika Gonzalez, Jose Ezequiel Martin, Elena Molina, Maitane Mugica, Ainhoa Palacios, Iratxe Seoane, Naiara Gutiez, Estibaliz Atondo, Eneko Santos Fernández, Maddi Oyanguren, Borja Jimenez‐Lasheras, Ainize Peña‐Cearra, Ana M. Aransay, Asis Palazon, Aize Pellón, Leticia Abecia, Hector Rodriguez, Natalia Elguezabal, Juan Anguita   +24 more
wiley   +1 more source

Amplicon-based next-generation sequencing reveals the co-existence of multiple Leishmania species in patients with visceral leishmaniasis

International Journal of Infectious Diseases, 2022
: Visceral leishmaniasis (VL) is a mammalian protozoal disease propagated in the Americas by female phlebotomine sandflies, mainly caused by Leishmania infantum.
Adriana Castillo-Castañeda, Luz H. Patiño, Marina Muñoz, Martha S. Ayala, Maryi Segura, Jessica Bautista, Maryia V. Shaban, Alberto Paniz-Mondolfi, Juan David Ramírez   +8 more
doaj   +1 more source

Transmission potential of paromomycin-resistant Leishmania infantum and Leishmania donovani

Journal of Antimicrobial Chemotherapy, 2019
AbstractObjectivesFormer studies demonstrated quick selection of paromomycin resistance for Leishmania infantum and Leishmania donovani accompanied by increased fitness. The present study aimed to interpret these findings in an epidemiological context by comparing infection of WT and experimentally derived paromomycin-resistant strains in the sand fly ...
G Caljon, P Volf, L Maes, J Sadlova, H Aslan, L Van Bockstal, S Hendrickx   +6 more
openaire   +2 more sources

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source

Structure of tyrosine aminotransferase fromLeishmania infantum [PDF]

Acta Crystallographica Section F Structural Biology Communications, 2014
The trypanosomatid parasiteLeishmania infantumis the causative agent of visceral leishmaniasis (VL), which is usually fatal unless treated. VL has an incidence of 0.5 million cases every year and is an important opportunistic co-infection in HIV/AIDS. Tyrosine aminotransferase (TAT) has an important role in the metabolism of trypanosomatids, catalyzing
Moreno, M. A., Abramov, A., Abendroth, J., Alonso, A., Zhang, S., Alcolea, P. J., Edwards, T., Lorimer, D., Myler, P. J., Larraga, V.   +9 more
openaire   +3 more sources

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]

, 2016
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E, Cruz Cervera, E, Diro, E, Getahun, M, Hailu, A, Kropf, P, Lemma, M, Melkamu, R, Mengesha, B, Mesfin, G, Modolell, M, Muller, I, Munder, M, Skhedy, Z, Tajebe, F, Takele, Y, Van der Auwera, G, Yardley, V, Yeshanew, A, Yizengaw, E   +19 more
core   +3 more sources