Results 81 to 90 of about 79,414 (305)

Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy.

, 2007
Leishmaniasis is a geographically widespread severe disease, with an increasing incidence of two million cases per year and 350 million people from 88 countries at risk. The causative agents are species of Leishmania, a protozoan flagellate.
Ayala, Francisco J, Chocholová, Eva, Dedet, Jean-Pierre, Dujardin, Jean-Claude, Haralambous, Christos, Horák, Ales, Jirků, Milan, Kuhls, Katrin, Lukes, Julius, Mauricio, Isabel L, Miles, Michael A, Oborník, Miroslav, Pratlong, Francine, Schönian, Gabriele, Soteriadou, Ketty, Tintaya, K Wilber Quispe   +15 more
core   +2 more sources

Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives

ChemMedChem, EarlyView.
Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi, Nicoletta Basilico, Erika Iervasi, Chiara Brullo, Silvia Parapini, Marco Ponassi, Camillo Rosano, Andrea Spallarossa   +7 more
wiley   +1 more source

Leishmania infantum induces high phagocytic capacity and intracellular nitric oxide production by human proinflammatory monocyte [PDF]

Memorias do Instituto Oswaldo Cruz
BACKGROUND The mechanism of resistance to SbIII in Leishmania is complex, multifactorial and involves not only biochemical mechanisms, but also other elements, such as the immune system of the host.
Christiana Vargas Ribeiro, Bruna Fonte Boa Rocha, Edward Oliveira, Andrea Teixeira-Carvalho, Olindo Assis Martins-Filho, Silvane Maria Fonseca Murta, Vanessa Peruhype-Magalhães   +6 more
doaj   +2 more sources

The Gut Microbiome of the Vector Lutzomyia longipalpis Is Essential for Survival of Leishmania infantum

mBio, 2017
The vector-borne disease leishmaniasis, caused by Leishmania species protozoa, is transmitted to humans by phlebotomine sand flies. Development of Leishmania to infective metacyclic promastigotes in the insect gut, a process termed metacyclogenesis, is ...
Patrick H. Kelly, S. Bahr, T. D. Serafim, N. Ajami, J. Petrosino, C. Meneses, J. Kirby, J. Valenzuela, S. Kamhawi, M. Wilson   +9 more
semanticscholar   +1 more source

Leishmaniasis: new approaches to disease control. [PDF]

, 2003
The leishmaniases afflict the world's poorest populations. Among the two million new cases each year in the 88 countries where the disease is endemic (fig 1), it is estimated that 80% earn less than $2 a day.
Croft, Simon L, Davies, Clive R, Kaye, Paul, Sundar, Shyam   +3 more
core   +2 more sources

Artificial Intelligence in Veterinary Clinical Pathology—An Introduction and Review

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Artificial intelligence (AI), particularly through machine learning and deep learning, presents opportunities for the enhancement of the workflow of the veterinary clinical pathologist. This review introduces basic concepts in AI in a nontechnical manner and explores the qualification and integration of AI in veterinary clinical pathology. The
Samuel V. Neal, Daniel G. Rudmann, Kara N. Corps   +2 more
wiley   +1 more source

Mucocutaneous Leishmaniasis due to Leishmania infantum Infection

Acta Dermato-Venereologica, 2022
Abstract is missing (Short communcation)
Kai-Philipp Linse, Christian Bogdan, Holger A. Haenssle, Ferdinand Toberer   +3 more
openaire   +3 more sources

In Vitro and In Vivo Effectiveness of Carvacrol, Thymol and Linalool against Leishmania infantum

Molecules, 2019
Background: One of the most important causative agents of visceral leishmaniasis (VL) is Leishmania infantum, which is mainly spread by Phlebotomus and Lutzomyia sandflies in the Old and New World, respectively.
M. Youssefi, E. Moghaddas, M. A. Tabari, A. Moghadamnia, S. M. Hosseini, B. R. H. Farash, M. Ebrahimi, Niki Nabavi Mousavi, A. Fata, F. Maggi, R. Petrelli, S. Dall'acqua, G. Benelli, S. Sut   +13 more
semanticscholar   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, EarlyView.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

Seasonal Dynamics of Phlebotomine Sand Fly Species Proven Vectors of Mediterranean Leishmaniasis Caused by Leishmania infantum

PLoS Neglected Tropical Diseases, 2016
Background The recent geographical expansion of phlebotomine vectors of Leishmania infantum in the Mediterranean subregion has been attributed to ongoing climate changes.
B. Alten, C. Maia, M. Afonso, L. Campino, M. Jiménez, Estela González, R. Molina, A. Bañuls, J. Prudhomme, B. Vergnes, C. Toty, Cécile Cassan, N. Rahola, M. Thierry, D. Sereno, G. Bongiorno, R. Bianchi, C. Khoury, N. Tsirigotakis, E. Dokianakis, M. Antoniou, Vasiliki Christodoulou, A. Mazeris, M. Karakuş, Y. Ozbel, S. K. Arserim, Ozge Erisoz Kasap, F. Gunay, G. Oguz, S. Kaynaş, N. Tsertsvadze, Lamzira Tskhvaradze, E. Giorgobiani, M. Gramiccia, P. Volf, L. Gradoni   +35 more
semanticscholar   +1 more source