Results 111 to 120 of about 66,437 (256)
BioMed Research International, 2015 This study was designed to assess in vitro metacyclogenesis of Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis clinical field isolates obtained from patient lesions (L. braziliensis IMG3 and PPS6m; L.
I. A. da Silva +7 more
semanticscholar +1 more source
The American Journal of Tropical Medicine and Hygiene, 2003 We describe the pathologic alterations of the central nervous system (CNS) observed in experimental tegumentary leishmaniasis in BALB/c and Swiss mice. The mice were subcutaneously infected with 104 amastigotes of Leishmania (Leishmania) amazonensis. Animals were killed and brains were removed for histologic and immunocytochemical studies.
Abreu-Silva, Ana Lucia +4 more
openaire +2 more sources
The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease
Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira +2 more
wiley +1 more source
New delivery systems for amphotericin B applied to the improvement of leishmaniasis treatment [PDF]
, 2016 © 2015, Sociedade Brasileira de Medicina Tropical. All rights reserved. Leishmaniasis is one of the six major tropical diseases targeted by the World Health Organization.
Chávez-Fumagalli, Miguel A. +2 more
core +1 more source
Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues +6 more
wiley +1 more source
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.ABSTRACT Essential oils are rich in bioactive molecules like terpenes and phenolic compounds, but have low yields, making process efficiency crucial. Enzyme‐assisted hydrodistillation is a sustainable alternative, enhancing oil release by degrading the cell wall.
Júlio César Gonçalves de Souza +7 more
wiley +1 more source
Semina: Ciências Agrárias, 2012 Leishmaniasis are antropozoonoses involving various species of Leishmania and hosts, with variable clinical presentations and considered of great importance to public health.
Patrícia Mendes Pereira +5 more
doaj
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.ABSTRACT Biodiversity offers a rich source of bioactive compounds for drug discovery. We isolated Aspergillus fumigatus from compost in the Atlantic Forest and found its extract active against Leishmania (Leishmania) amazonensis. Two crude extracts, I06 and I75, were selected for further study.
Juliana Cristina Pereira Calado +11 more
wiley +1 more source
Leishmania-specific surface antigens show sub-genus sequence variation and immune recognition. [PDF]
, 2010 A family of hydrophilic acylated surface (HASP) proteins, containing extensive and variant amino acid repeats, is expressed at the plasma membrane in infective extracellular (metacyclic) and intracellular (amastigote) stages of Old World Leishmania ...
Depledge, DP +7 more
core
Theranostic applications of phage display to control leishmaniasis: Selection of biomarkers for serodiagnostics, vaccination, and immunotherapy [PDF]
, 2017 © 2015, Sociedade Brasileira de Medicina Tropical. All rights reserved. Phage display is a high-throughput subtractive proteomic technology used for the generation and screening of large peptide and antibody libraries.
Chávez-Fumagalli, Miguel A. +5 more
core +1 more source