Antigenic profiling of Leishmania amazonensis microsomal fraction to support vaccine development. [PDF]
Fernandes JMP +9 more
europepmc +1 more source
Impact of Bacterial Membrane Vesicles on Cellular Responses in Leishmania amazonensis-Infected Macrophages In Vitro. [PDF]
Gallo-Francisco PH +9 more
europepmc +1 more source
Lipid Mediators in Host-Pathogen Interactions during <i>Leishmania</i> Infection: Friends or Foes? [PDF]
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Anti-Leishmania activated C-kinase monoclonal antibody immunohistochemical technique for cutaneous leishmaniasis diagnosis. [PDF]
Santos ADL +11 more
europepmc +1 more source
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In vitro activity of cinnamaldehyde on Leishmania (Leishmania) amazonensis
Experimental Parasitology, 2022Tegumentary leishmaniasis is an endemic disease that urgently needs new and effective treatments. L. amazonensis is one of the main species involved in the transmission of this infectious and non-contagious disease. The currently available treatments for leishmaniasis have high toxicity and vary in efficacy.
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Antileishmanial activity of cordiaquinone E towards Leishmania (Leishmania) amazonensis
International Immunopharmacology, 2021Leishmaniasis is caused by several protozoan species of Leishmania, and being endemically present in 98 countries around the world, it is also a severe public-health problem. The available antileishmanial drugs are toxic and yet present risks of recurrent infection. Efforts to find new, effective, and safe oral agents for the treatment of leishmaniasis
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Although bats are one of the most abundant mammals in the new world and are present in virtually all ecosystems, including urban and peri-urban environments, few studies have investigated the role of these animals in the epidemiological chain of leishmaniosis.
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Leishmania amazonensis response to artemisinin and derivatives
Parasitology International, 2021The worldwide presence of Leishmania parasites increases in the poorest regions. Current leishmaniasis treatments are unsatisfactory due to resistance development, side effects and cost. Herein, we describe the in vitro activity of artemisinin (ART), artemether (ATM), artesunate (ATS) and dihydroartemisinin (DHA) against Leishmania amazonensis ...
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Characterization of Leishmania (Leishmania) amazonensis promastigotes resistant to pentamidine
Experimental Parasitology, 2008Pentamidine is a second-line agent used in the treatment of leishmaniasis and its mode of action and mechanism of resistance is not well understood. It was previously demonstrated that transfection of promastigotes and amastigotes with the ABC transporter PRP1 gene confers resistance to pentamidine.
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