Design of primer pairs for species-specific diagnosis of Leishmania (Leishmania) infantum chagasi using PCR [PDF]
The objective of this study was to design and evaluate new primers for species-specific detection of L. infantum chagasi using PCR. Two combinations of primer pairs were established with the aim of obtaining specific amplification products from the L. infantum chagasi 18S rRNA gene.
Osvaldo José, da Silveira Neto +3 more
openaire +5 more sources
SUMMARY American tegumentary leishmaniasis (ATL) is an infectious disease caused by protozoa of the genus Leishmania, and transmitted by sandflies. In the state of Rio de Janeiro, almost all of the cases of American tegumentary leishmaniasis (ATL) are ...
Marcelo Rosandiski LYRA +6 more
doaj +1 more source
LXR deficiency confers increased protection against visceral Leishmania infection in mice. [PDF]
The liver X receptors (LXRs) are a family of nuclear receptor transcription factors that are activated by oxysterols and have defined roles in both lipid metabolism and cholesterol regulation.
Kevin W Bruhn +10 more
doaj +1 more source
Leishmania infantum versus Leishmania chagasi: do not forget the law of priority [PDF]
(Diptera:Psychodidae) and visceral leishmaniasis (VL) in the Ameri-cas, with particular attention to the eco-epidemiology ofdisease in Brazil. In their review, they have discussed withproperty the taxonomic position and origin of the causalagent of the disease.
openaire +4 more sources
Attenuation of Leishmania infantum chagasi Metacyclic Promastigotes by Sterol Depletion [PDF]
ABSTRACTThe infectious metacyclic promastigotes ofLeishmaniaprotozoa establish infection in a mammalian host after they are deposited into the dermis by a sand fly vector. SeveralLeishmaniavirulence factors promote infection, including the glycosylphosphatidylinositol membrane-anchored major surface protease (MSP).
Chaoqun, Yao +6 more
openaire +2 more sources
Field ecology of sylvatic Rhodnius populations (Heteroptera, Triatominae): risk factors for palm tree infestation in western Ecuador. [PDF]
Most Rhodnius species (Triatominae) are primarily associated with palm trees. They maintain enzootic Trypanosoma cruzi transmission and are responsible for human infection (causing Chagas disease) through the Neotropics. Assessing whether individual palm
Ho, A. Y. Q. +5 more
core +4 more sources
Leishmania infantum ecto-nucleoside triphosphate diphosphohydrolase-2 is an apyrase involved in macrophage infection and expressed in infected dogs. [PDF]
Visceral leishmaniasis is an important tropical disease, and Leishmania infantum chagasi (synonym of Leishmania infantum) is the main pathogenic agent of visceral leishmaniasis in the New World. Recently, ecto-nucleoside triphosphate diphosphohydrolases (
Raphael De Souza Vasconcellos +19 more
doaj +1 more source
Lutzomyia migonei is a permissive vector competent for Leishmania infantum [PDF]
BACKGROUND: Leishmania infantum is the most widespread etiological agent of visceral leishmaniasis (VL) in the world, with significant mortality rates in human cases.
Jitka Myskova +6 more
core +1 more source
Among mammals, the canids are most often infected by Leishmania sp. This paper reports the occurrence of Leishmania (Leishmania) infantum chagasi as well as the presence of intranuclear inclusions resembling viral particles of canine adenovirus-1 in a ...
Luciano Nakazato +5 more
doaj +1 more source
Heterogeneity of Leishmania infantum chagasi Kinetoplast DNA in Teresina (Brazil) [PDF]
Leishmania infantum chagasi is the causative agent of visceral leishmaniasis in Brazil. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis of kinetoplast DNA (kDNA) minicircles was used to evaluate genetic profiles of 48 Leishmania infantum chagasi strains from dog and human parasite cultures, fresh collected dog ...
Diego Peres, Alonso +4 more
openaire +2 more sources

