Results 121 to 130 of about 5,616,372 (322)

A Comprehensive Review of Cutaneous Leishmaniasis in Kerman Province, Southeastern Iran- Narrative Review Article

Iranian Journal of Public Health, 2015
Background: Cutaneous leishmaniasis (CL) remains a serious public health concern in Kerman Province, eastern Iran. This study was aimed to conduct a comprehensive review and highlights various aspects of CL in the province of Kerman.
Iraj Sharifi, Mohammad Reza Aflatoonian, Ali Reza Fekri, Maryam Hakimi Parizi, Abbas Aghaei Afshar, Ahmad Khosravi, Fatemeh Sharifi, Behnaz Aflatoonian, Ali Khamesipour, Yahya Dowlati, Farrokh Modabber, Abolhasan Nadim   +11 more
doaj  

Leishmania spp Infection in Patients and Great Gerbils (Rhombomys opimus) in a High-Risk Focus of Zoonotic Cutaneous Leishmaniasis in Central Iran: a Microscopic and Molecular Survey

Journal of Arthropod-Borne Diseases
Background: Zoonotic cutaneous leishmaniasis (ZCL) is an endemic disease in Varzaneh City where Leishmania ma­jor is the causative agent and the great gerbil, Rhombomys opimus, is the main reservoir host of the disease.
Narges Marvi Moghadam, Mehdi Mohebali, Yavar Rassi, Ali Reza Zahraei-Ramazani, Mohammad Ali Oshaghi, Reza Jafari, Mahboubeh Fatemi, Mohammad Hossein Arandian, Hamid Abdoli, Nilufar Shareghi, Maryam Ghanei, Nilufar Jalali-Zand, Arshad Veysi, Javad Ramazanpoor, Kurosh Aminian, Ali Salehi, Ali Khamesipour, Amir Ahmad Akhavan   +17 more
doaj   +1 more source

Rapamycin Exerts Its Geroprotective Effects in the Ageing Human Immune System by Enhancing Resilience Against DNA Damage

Aging Cell, Volume 25, Issue 2, February 2026.
Using in vitro DNA damage assays in human T cells, ex vivo profiling of aged immune subsets and a small placebo‐controlled in vivo study, authors show that low‐dose rapamycin, a potent life‐extending mTOR inhibitor, enhances resilience against DNA damage in the human immune system.
Loren Kell, Eleanor J. Jones, Nima Gharahdaghi, Daniel J. Wilkinson, Kenneth Smith, Philip J. Atherton, Anna K. Simon, Lynne S. Cox, Ghada Alsaleh   +8 more
wiley   +1 more source

Aspects épidemiocliniques et évolutifs chez 157 cas de leishmaniose cutanée au Maroc

The Pan African Medical Journal, 2014
Connue au Maroc depuis la fin du XIX siècle, la leishmaniose cutanée (LC) constitue un problème de santé publique dans notre pays. Le but de notre travail est de décrire le profil épidémioclinique et l'évolution post thérapeutique chez les patients ayant
Naoufal Hjira, Rachid Frikh, Tarik Marcil, Hanane Lamsyah, Siham Oumakhir, Noureddine Baba, Mohammed Boui   +6 more
doaj   +1 more source

Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking

Scientific Reports, 2015
Leishmaniasis is a neglected vector-born disease caused by a protozoan of the genus Leishmania and affecting more than 1.300.000 people worldwide. The couple tryparedoxin/tryparedoxin peroxidase is essential for parasite survival in the host since it ...
M. Brindisi, Simone Brogi, Nicola Relitti, A. Vallone, S. Butini, S. Gemma, E. Novellino, G. Colotti, G. Angiulli, Francesco Di Chiaro, A. Fiorillo, A. Ilari, G. Campiani   +12 more
semanticscholar   +1 more source

Serosurveillance of Leishmania infantum in Zoo‐Kept Animals in Spain

Zoonoses and Public Health, Volume 73, Issue 1, Page 65-73, February 2026.
ABSTRACT Introduction Leishmaniosis is a sand fly‐borne zoonosis mainly caused by Leishmania infantum in Europe. Exposure to this protozoan has been widely reported in many domestic and wild species. However, epidemiological surveys evaluating the circulation of L. infantum in zoo‐kept animals remain limited. This large‐scale study aims to evaluate the
Jesús Barbero‐Moyano, Diana Marteles, David Cano‐Terriza, Sergio Villanueva‐Saz, Moisés Gonzálvez, Pablo Quilez, Adrián Beato‐Benítez, Javier Martínez, Alfredo Gargallo‐Martín, Pilar Soriano, María A. Risalde, Ignacio García‐Bocanegra   +11 more
wiley   +1 more source

Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy.

, 2007
Leishmaniasis is a geographically widespread severe disease, with an increasing incidence of two million cases per year and 350 million people from 88 countries at risk. The causative agents are species of Leishmania, a protozoan flagellate.
Ayala, Francisco J, Chocholová, Eva, Dedet, Jean-Pierre, Dujardin, Jean-Claude, Haralambous, Christos, Horák, Ales, Jirků, Milan, Kuhls, Katrin, Lukes, Julius, Mauricio, Isabel L, Miles, Michael A, Oborník, Miroslav, Pratlong, Francine, Schönian, Gabriele, Soteriadou, Ketty, Tintaya, K Wilber Quispe   +15 more
core   +2 more sources

Intracellular Survival of Leishmania major Depends on Uptake and Degradation of Extracellular Matrix Glycosaminoglycans by Macrophages

PLoS Pathogens, 2015
Leishmania parasites replicate within the phagolysosome compartment of mammalian macrophages. Although Leishmania depend on sugars as a major carbon source during infections, the nutrient composition of the phagolysosome remains poorly described.
Thomas Naderer, Joanne Heng, Eleanor C. Saunders, Joachim Kloehn, T. Rupasinghe, T. Brown, M. McConville   +6 more
semanticscholar   +1 more source

Anti-leishmanial, immunomodulatory and anti-oxidative activity of quercetin against cutaneous leishmaniasis caused by Leishmania major

, 2023
Ahmad Oryan, Effat Bemani, Somayeh Bahrami   +2 more
openalex   +1 more source

First detection of Leishmania major in dogs living in an endemic area of zoonotic cutaneous leishmaniasis in Tunisia

Parasites & Vectors
Abstract Background Dogs are considered the main domestic animals that may be a reservoir for Leishmania infantum, the agent of zoonotic visceral leishmaniasis (ZVL) in several countries of the world.
Maria Paola Maurelli, Lilia Zribi, Nour El Houda Ben Fayala, Valentina Foglia Manzillo, Ines Balestrino, Noureddine Hamdi, Aida Bouratbine, Manuela Gizzarelli, Laura Rinaldi, Karim Aoun, Gaetano Oliva   +10 more
doaj   +1 more source