Results 11 to 20 of about 76,622 (282)

The SNARE protein family of Leishmania major [PDF]

BMC Genomics, 2006
Abstract Background Leishmania major is a protozoan parasite with a highly polarised cell shape that depends upon endocytosis and exocytosis from a single area of the plasma membrane, the flagellar pocket.
Besteiro, S., Coombs, G.H., Mottram, J.C.   +2 more
openaire   +4 more sources

Increased transmission potential of Leishmania major/Leishmania infantum hybrids [PDF]

International Journal for Parasitology, 2007
Development of Leishmania infantum/Leishmania major hybrids was studied in two sand fly species. In Phlebotomus papatasi, which supported development of L. major but not L. infantum, the hybrids produced heavy late-stage infections with high numbers of metacyclic promastigotes.
Petr, Volf, Ivana, Benkova, Jitka, Myskova, Jovana, Sadlova, Lenea, Campino, Christophe, Ravel   +5 more
openaire   +2 more sources

The LPG1 gene family of Leishmania major [PDF]

Molecular and Biochemical Parasitology, 2004
In Leishmania major, the core of the abundant surface lipophosphoglycan (LPG) is structurally related to that of the smaller glycosylinositolphospholipids (GIPLs) in containing galactosylfuranose (Gal(f)) residues in a Gal(f) (beta1, 3)Man motif. However, deletion of the putative Gal(f)-transferase (Gal(f)T) LPG1 affected Gal(f) incorporation in LPG ...
Kai, Zhang, Tamara, Barron, Salvatore J, Turco, Stephen M, Beverley   +3 more
openaire   +2 more sources

Treatment Outcome of the Drug-resistant Zoonotic Cutaneous Leishmaniasis by Glucantime

Advanced Biomedical Research, 2017
Background: Resistance of Leishmania species to antimonial drugs has increased. Hence, in the present study Leishmania major isolates were collected from patients with resistance phenotype and the presence/absence of resistance to Glucantime was ...
Simindokht Soleimanifard, Reza Arjmand, Sedighe Saberi, Mansoor Salehi, Seyed Hossain Hejazi   +4 more
doaj   +1 more source

Analysis by RNA-seq of transcriptomic changes elicited by heat shock in Leishmania major [PDF]

, 2019
Besides their medical relevance, Leishmania is an adequate model for studying post-transcriptional mechanisms of gene expression. In this microorganism, mRNA degradation/stabilization mechanisms together with translational control and post-translational ...
Aguado, Begoña, Corvo, Laura, Lombraña, Rodrigo, Rastrojo, Alberto, Requena, Jose M., Solana, Jose C.   +5 more
core   +2 more sources

Plasmenylethanolamine synthesis in Leishmania major [PDF]

Molecular Microbiology, 2016
SummaryEthanolamine glycerophospholipids are ubiquitous cell membrane components. Trypanosomatid parasites of the genus Leishmania synthesize the majority of their ethanolamine glycerophospholipids as 1‐O‐alk‐1′‐enyl‐2‐acyl‐sn‐glycero‐3‐phosphoethanolamine or plasmenylethanolamine (PME) through the Kennedy pathway.
Pawlowic, Mattie C., Hsu, Fong Fu, Moitra, Samrat, Biyani, Neha, Zhang, Kai   +4 more
openaire   +3 more sources

Separation and evaluation of natural antileishmanial potential against Leishmania major and infuntum isolated from the Tunisia strains

Bangladesh Journal of Pharmacology, 2018
Besides its nutritional value as a dietary supplement, Tribulus terrestris is used as a remedy for fertility disorder in Ayurveda and Chinese medicine as well as by modern herbalists.
Salwa Bouabdallah, Dhafer Laouini, Nabiha Bouzouita, Safia El-Bok, Rabiaa M. Sghaier, Sawssen Selmi, Mossadok Ben Attia   +6 more
doaj   +1 more source

Insights on adaptive and innate immunity in canine leishmaniosis [PDF]

, 2016
Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a systemic disease, which can present with variable clinical signs, and clinicopathological abnormalities.
Abi Abdallah, Alexander, Catchpole, DAMER P. BLAKE, de Souza Carmo, Green, Kensil, LAIA SOLANO-GALLEGO, Lopez, Margarito, Ordeix, Pinelli, Pitta, Quinnell, Sadick, Sanchez, SHAZIA HOSEIN, Silva, Vouldoukis, Wakelin   +19 more
core   +4 more sources

The Genome of the Kinetoplastid Parasite, Leishmania major [PDF]

Science, 2005
Leishmania species cause a spectrum of human diseases in tropical and subtropical regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase haploid genome of Leishmania major (Friedlin strain) and predict 911 RNA genes, 39 pseudogenes, and 8272 protein-coding genes, of which 36% can
Ivens, A.C., Peacock, C.S., Worthey, E.A., Murphy, L., Aggarwal, G., Berriman, M., Sisk, E., Rajandream, M.A., Adlem, E., Aert, Rita, Anupama, A., Myler, P.J., Apostolou, Z., Attipoe, P., Bason, N., Bauser, C., Beck, A., Beverley, S.M., Bianchettin, G., Borzym, K., Bothe, G., Bruschi, C.V., Collins, M., Cadag, E., Ciarloni, L., Clayton, C., Coulson, R.MR., Cronin, A., Cruz, A.K., Davies, R.M., De Gaudenzi, J., Dobson, D.E., Duesterhoeft, A., Fazelina, G., Fosker, N., Frasch, A.C., Fraser, A., Fuchs, M., Gabel, C., Goble, A., Goffeau, A., Harris, D., Hertz-Fowler, C., Hilbert, H., Horn, D., Huang, Y.T., Klages, S., Knights, A., Kube, M., Larke, N., Litvin, L., Lord, A., Louie, T., Marra, M., Masuy, D., Matthews, K., Michaeli, S., Mottram, J.C., Muller-Auer, S., Munden, H., Nelson, S., Norbertczak, H., Oliver, K., O'Neil, S., Pentony, M., Pohl, T.M., Price, C., Purnelle, B., Quail, M.A., Rabbinowitsch, E., Reinhardt, R., Rieger, M., Rinta, J., Robben, Johan, Robertson, L., Ruiz, J.C., Rutter, S., Saunders, D., Schafer, M., Schein, J., Schwartz, D.C., Seeger, K., Seyler, A., Sharp, S., Shin, H., Sivam, D., Squares, R., Squares, S., Tosato, V., Vogt, C., Volckaert, Guido, Wambutt, R., Warren, T., Wedler, H., Woodward, J., Zhou, S.G., Zimmermann, W., Smith, D.F., Blackwell, J.M., Stuart, K.D., Barrell, B.   +100 more
openaire   +5 more sources

Updates on Geographical Dispersion of Leishmania Parasites Causing Cutaneous Affections in Algeria

Pathogens, 2021
Leishmaniases are neglected tropical diseases of public health concern in Algeria. To update the geographical distribution of Leishmania spp. causing cutaneous affection, we examined a set of Giemsa-stained smears prepared from skin lesions of the ...
Arezki Izri, Amina Bendjaballah-Laliam, Denis Sereno, Mohammad Akhoundi   +3 more
doaj   +1 more source