Results 11 to 20 of about 5,616,372 (322)
A dhfr-ts- Leishmania major Knockout Mutant Cross-protects against Leishmania amazonensis [PDF]
Memorias do Instituto Oswaldo Cruz, 1999 E10-5A3 is a dhfr-ts- Leishmania major double knockout auxotrophic shown previously to induce substantial protection against virulent L. major infection in both genetically susceptible and resistant mice.
PST Veras +8 more
doaj +4 more sources
Plasmenylethanolamine synthesis in Leishmania major [PDF]
Molecular Microbiology, 2016 SummaryEthanolamine glycerophospholipids are ubiquitous cell membrane components. Trypanosomatid parasites of the genus Leishmania synthesize the majority of their ethanolamine glycerophospholipids as 1‐O‐alk‐1′‐enyl‐2‐acyl‐sn‐glycero‐3‐phosphoethanolamine or plasmenylethanolamine (PME) through the Kennedy pathway.
M. Pawlowic +4 more
semanticscholar +4 more sources
Clinical Presentation of Cutaneous Leishmaniasis caused by Leishmania major [PDF]
BMC Genomics, 2017 Abstract Background Leishmania major is a protozoan parasite with a highly polarised cell shape that depends upon endocytosis and exocytosis from a single area of the plasma membrane, the flagellar pocket.
Latifa Remadi +8 more
semanticscholar +5 more sources
Increased transmission potential of Leishmania major/Leishmania infantum hybrids [PDF]
International Journal for Parasitology, 2007 Development of Leishmania infantum/Leishmania major hybrids was studied in two sand fly species. In Phlebotomus papatasi, which supported development of L. major but not L. infantum, the hybrids produced heavy late-stage infections with high numbers of metacyclic promastigotes.
Petr, Volf +5 more
openaire +2 more sources
Cloning of Leishmania Major P4 Gene [PDF]
Cell Journal, 2008 Objective: Leishmania major P4 gene is normally expressed during amastigote form ofthe parasite and can be good candidate for producing an effective vaccine.
Minoo Shaddel +4 more
doaj +1 more source
Iranian Journal of Parasitology, 2023 Background: Cutaneous leishmaniasis (CL) is an endemic infection in the Middle East, including Iran that is also spreading to new foci. We aimed to determine the leishmaniasis species causing CL in Alborz province.
Susan Sheikhi +7 more
doaj +1 more source
Structure ofLeishmania majorcysteine synthase [PDF]
Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2012 Cysteine biosynthesis is a potential target for drug development against parasiticLeishmaniaspecies; these protozoa are responsible for a range of serious diseases. To improve understanding of this aspect ofLeishmaniabiology, a crystallographic and biochemical study ofL.
Fyfe, Paul K +5 more
openaire +4 more sources
Comparative Gene Expression Profiles of Leishmania major and Leishmania infantum Promastigotesa
Turkiye parazitolojii dergisi, 2021 This study aimed to determine the differences between the gene expression profiles of Leismania major and Leishmania infantum promastigotes through comparative analysis of gene expressions.Cell culture of L. major (MHOM/IL/80) and L. infantum (MHOM/MA/67/ITMAP/263) cell lines was performed.
Özlem Ulusan Bağcı +2 more
openaire +3 more sources
The first detection of Leishmania major in naturally infected Sergentomyia minuta in Portugal [PDF]
, 2013 Phlebotomine sandflies of the genus Sergentomyia are widely distributed throughout the Old World. It has been suggested that Sergentomyia spp are involved in the transmission of Leishmania in India and Africa, whereas Phlebotomus spp are thought to be ...
Afonso, Maria Odete +5 more
core +3 more sources
In Vitro Screening Test Using Leishmania Promastigotes Stably Expressing mCherry Protein [PDF]
, 2014 Transgenic Leishmania major and Leishmania donovani axenic promastigotes constitutively expressing mCherry were used for in vitro antileishmanial drug screening. This method requires minimal sample manipulation and can be easily adapted to automatic drug
Miguel A. Morales, Vacchina, Paola
core +2 more sources