Results 171 to 180 of about 8,190 (198)
Some of the next articles are maybe not open access.
Amine production byLeishmania mexicana
Annals of Tropical Medicine & Parasitology, 1985Growing promastigotes of Leishmania mexicana mexicana excreted large amounts of urea and ammonia into the culture medium. Both promastigotes and amastigotes in short-term, high-density cultures also produced urea and ammonia; the excretion rate was higher in promastigotes.
G H, Coombs, B E, Sanderson
openaire +2 more sources
Chromosome rearrangement in Leishmania mexicana M379
Molecular and Biochemical Parasitology, 1991Circular extrachromosomal elements were observed in a variety of Leishmania species. We show here that two lines originating from the same isolate have been found to contain a circular DNA molecule of 26.6 kb and a linear chromosome of about 250 kb, respectively, which share a homology of more than 20 kb.
Liu, J. +9 more
openaire +2 more sources
The Leishmania mexicana proteasome
Molecular and Biochemical Parasitology, 1999As a start to understanding the importance of intracellular proteolysis in the protozoon Leishmania mexicana, the parasite proteasome has been purified and characterised. The L. mexicana proteasome is similar to proteasomes from other eukaryotes. It is soluble, and the 20S form has a mass of around 670 kDa, composed of at least 10 distinct subunits in ...
openaire +2 more sources
Subcellular localisation of purinemetabolising enzymes in Leishmania mexicana mexicana
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1985Leishmania mexicana mexicana cultured promastigotes were fractionated by isopycnic centrifugation on linear sucrose gradients. Guanine, hypoxanthine and xanthine phosphoribosyltransferase activities were found to be associated with glycosomes, whereas adenine phosphoribosyltransferase was cytosolic.
H F, Hassan, J C, Mottram, G H, Coombs
openaire +2 more sources
Purine phosphoribosyltransferases of Leishmania mexicana mexicana and other flagellate protozoa
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1985Amastigotes and cultured promastigotes of Leishmania mexicana mexicana and L. m. amazonensis, cultured promastigotes of L. donovani and L. tarentolae, and the culture forms of Crithidia fasciculata, Herpetomonas muscarum muscarum and H. m. ingenoplastis all possessed four phosphoribosyltransferase (PRTase) activities: adenine PRTase, hypoxanthine ...
H F, Hassan, G H, Coombs
openaire +2 more sources
Mastomys natalensis as an experimental host for Leishmania mexicana mexicana
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1978Young multimammate rats (Mastomys natalensis) can be readily infected when inoculated intradermally with the amastigotes of Leishmania mexicana mexicana. Lesions appear at the site of inoculation in the second week of infection and continue to increase in size for the first month; amastigotes can be detected during this period.
L H, Pereira +6 more
openaire +2 more sources
Leishmania mexicana mexicana gp63 is a site-specific neutral endopeptidase
Molecular and Biochemical Parasitology, 1990Leishmania mexicana, like other species of the genus, has a major 63-kDa surface glycoprotein (gp63) that is an active protease. Reports differ as to whether gp63 is a neutral or an acidic protease. Using three radiolabeled synthetic peptide substrates, gp63 purified from L. m.
H S, Ip +3 more
openaire +2 more sources
Glucose transport in amastigotes and promastigotes of Leishmania mexicana mexicana
Molecular and Biochemical Parasitology, 1995Promastigotes and amastigotes of Leishmania mexicana mexicana transported 2-deoxy-D-glucose (2-DOG) by a saturable process with a Km of 24 +/- 3 microM and Vmax of 2.21 nmol min-1 (mg protein)-1 for the promastigote and a Km of 29 +/- 8 microM and Vmax of 0.13 nmol min-1 (mg protein)-1 for the amastigote stage.
R J, Burchmore, D T, Hart
openaire +2 more sources
Inducible protein stabilization system in Leishmania mexicana
Molecular and Biochemical Parasitology, 2017Targeted regulation of protein levels is an important tool to investigate the role of proteins essential for cell function and development. In recent years, methods based on the Escherichia coli dihydrofolate reductase destabilization domain (ecDHFR DD) have been established and used in various cell types.
Lucie, Podešvová +2 more
openaire +2 more sources
Leishmania mexicana: promastigotes migrate through osmotic gradients
Experimental Parasitology, 2002During the insect phase of the parasite lifecycle, Leishmania promastigotes move from the midgut to the anterior regions of the alimentary tract of their sandfly vector. Chemotaxis of Leishmania promastigotes towards sugars has been reported, and the putative presence of sugar gradient in the insect foregut has been suggested to play a role in ...
Graham, Leslie +2 more
openaire +2 more sources