Results 211 to 220 of about 15,700 (261)

Leishmania tropica and Leishmania mexicana: Cross-immunity in mice

Experimental Parasitology, 1978
Abstract The effect of a previous or concurrent Leishmania tropica major infection on a L. mexicana infection was studied. Mice which were recovering from or had recovered from a L. tropica infection were found to be totally resistant to L. mexicana. Infection of mice already carrying a L. mexicana infection with L.
J, Alexander, R S, Phillips
openaire   +2 more sources

Pentose phosphate metabolism in Leishmania mexicana

Molecular and Biochemical Parasitology, 2003
The metabolism of pentose phosphates was studied in Leishmania mexicana promastigotes. Each of the enzymes of the classical pentose phosphate pathway (PPP) has been identified and specific activities measured. Functioning of the PPP was demonstrated in non-growing cells by measuring the evolution of 14CO2 from [1-14C]D-glucose and [6-14C]D-glucose ...
Dante Abel, Maugeri, Juan Jose, Cazzulo, Richard J S, Burchmore, Michael P, Barrett, Patrick O J, Ogbunude   +4 more
openaire   +2 more sources

Heme binding to Leishmania mexicana amazonensis

Molecular and Biochemical Parasitology, 1988
Leishmania mexicana amazonensis is a pathogenic parasite whose growth, due to a biosynthetic deficiency, is dependent on a supply of exogenous heme. Utilizing [55Fe]hemin, we have demonstrated that heme binding to non-dividing cultured promastigotes of L. m.
R A, Galbraith, M J, McElrath
openaire   +2 more sources

Amine production byLeishmania mexicana

Annals of Tropical Medicine & Parasitology, 1985
Growing promastigotes of Leishmania mexicana mexicana excreted large amounts of urea and ammonia into the culture medium. Both promastigotes and amastigotes in short-term, high-density cultures also produced urea and ammonia; the excretion rate was higher in promastigotes.
G H, Coombs, B E, Sanderson
openaire   +2 more sources

Chromosome rearrangement in Leishmania mexicana M379

Molecular and Biochemical Parasitology, 1991
Circular extrachromosomal elements were observed in a variety of Leishmania species. We show here that two lines originating from the same isolate have been found to contain a circular DNA molecule of 26.6 kb and a linear chromosome of about 250 kb, respectively, which share a homology of more than 20 kb.
Liu, J., Gajendran, N., Muthui, D., Muyldermans, S., Dujardin, J. C., De Doncker, S., Jacquet, D., Le Ray, D., Mathieu-Daudé, F., Hamers, R.   +9 more
openaire   +2 more sources

The Leishmania mexicana proteasome

Molecular and Biochemical Parasitology, 1999
As a start to understanding the importance of intracellular proteolysis in the protozoon Leishmania mexicana, the parasite proteasome has been purified and characterised. The L. mexicana proteasome is similar to proteasomes from other eukaryotes. It is soluble, and the 20S form has a mass of around 670 kDa, composed of at least 10 distinct subunits in ...
openaire   +2 more sources

Subcellular localisation of purinemetabolising enzymes in Leishmania mexicana mexicana

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1985
Leishmania mexicana mexicana cultured promastigotes were fractionated by isopycnic centrifugation on linear sucrose gradients. Guanine, hypoxanthine and xanthine phosphoribosyltransferase activities were found to be associated with glycosomes, whereas adenine phosphoribosyltransferase was cytosolic.
H F, Hassan, J C, Mottram, G H, Coombs
openaire   +2 more sources

Purine phosphoribosyltransferases of Leishmania mexicana mexicana and other flagellate protozoa

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1985
Amastigotes and cultured promastigotes of Leishmania mexicana mexicana and L. m. amazonensis, cultured promastigotes of L. donovani and L. tarentolae, and the culture forms of Crithidia fasciculata, Herpetomonas muscarum muscarum and H. m. ingenoplastis all possessed four phosphoribosyltransferase (PRTase) activities: adenine PRTase, hypoxanthine ...
H F, Hassan, G H, Coombs
openaire   +2 more sources

Mastomys natalensis as an experimental host for Leishmania mexicana mexicana

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1978
Young multimammate rats (Mastomys natalensis) can be readily infected when inoculated intradermally with the amastigotes of Leishmania mexicana mexicana. Lesions appear at the site of inoculation in the second week of infection and continue to increase in size for the first month; amastigotes can be detected during this period.
L H, Pereira, W, Mayrink, M, Dias, M S, Michalick, C A, Costa, P A, Magalhães, P, Williams   +6 more
openaire   +2 more sources

Leishmania mexicana mexicana gp63 is a site-specific neutral endopeptidase

Molecular and Biochemical Parasitology, 1990
Leishmania mexicana, like other species of the genus, has a major 63-kDa surface glycoprotein (gp63) that is an active protease. Reports differ as to whether gp63 is a neutral or an acidic protease. Using three radiolabeled synthetic peptide substrates, gp63 purified from L. m.
H S, Ip, A, Orn, D G, Russell, G A, Cross   +3 more
openaire   +2 more sources